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Mashup Score: 4Intrahepatic Exhausted Antiviral Immunity in an Immunocompetent Mouse Model of Chronic Hepatitis B - 1 month(s) ago
Targeting exhausted immune systems would be a promising therapeutic strategy to achieve a functional cure for HBV infection in patients with chronic hepatitis B (CHB). However, animal models recapitulating the immunokinetics of CHB are very limited. We aimed to develop an immunocompetent mouse model of CHB for intrahepatic immune profiling.
Source: www.cmghjournal.orgCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 22Current Issue Table of Contents: Gastroenterology - 1 month(s) ago
Login with your AGA username and password. Volume 165 Issue 2 p307-522,
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
Our August issue is online! Take a look inside: https://t.co/szUBnLjPDv https://t.co/TxPqNIvaKf
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Mashup Score: 15
In families with multiple cases of Crohn’s disease, unaffected members are 3 times more likely to develop the disease, possibly due to environmental factors rather than genetics.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
Study finds healthy first-degree relatives from multiplex families vs simplex families have higher subclinical intestinal inflammation, a distinct fecal microbial signature, and harbor a higher risk of developing #CrohnsDisease ➡️ https://t.co/il3z9ohBFz https://t.co/AAMiY1u6Ij
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Mashup Score: 8Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response - 2 month(s) ago
A comprehensive single-cell tumor and immune atlas of metastatic gastric adenocarcinomas is presented, uncovering molecular and cellular dynamics during metastasis and proposing a novel therapeutic strategy with potential clinical implications.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
📰 News alert: An article published last month in Gastroenterology on metastatic gastric cancer was recently mentioned in Oncology Times. Click the links below to view both publications! ⬇️ Gastro 🔗 https://t.co/SQubcCyPVu Oncology Times 🔗 https://t.co/lkALvjeW4S
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Mashup Score: 15Top 20 high-impact clinical research articles of 2024 - 2 month(s) ago
Our editors-in-chief share their selection of must-read clinical research articles from the past year.
Source: gastro.orgCategories: General Medicine News, GastroenterologyTweet-
Starting a new #GI project? 💡 Look back at some of the high-impact clinical research published in Gastro, @AGA_CGH, @AGA_TIGE, @AGA_GHAdvances in 2024: https://t.co/iFhT7mp6Be #GITwitter https://t.co/y5kWxgPGIC
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Mashup Score: 26Proteomic Biomarkers in Serum Predict Villous Atrophy Development in Asymptomatic Potential Celiac Disease Children at Time of Diagnosis - 2 month(s) ago
Potential celiac disease (PCD) is characterized by the presence of anti-tissue transglutaminase antibodies and normal intestinal architecture.1
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
In the largest biomarker validation study performed in cirrhosis, the GALAD score is better than alpha-fetoprotein (AFP) at detecting early stage HCC. 🔗https://t.co/L8CDLWq0Xq 🖋️ @ebtapper @serperm @juanpabloarab https://t.co/TbJBAb8Mez
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Mashup Score: 3Pragmatic Resect and Discard Implementation Using Computer-Assisted Optical Polyp Diagnosis - 2 month(s) ago
Histopathology assessment is the current standard of care for evaluating diminutive colorectal polyps. The
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
Research letter examines pragmatic resect and discard implementation using computer-assisted optical polyp diagnosis. Want to learn more? Click the link ➡️ https://t.co/kCWo6IuhoS https://t.co/kD9csUGnII
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Mashup Score: 10Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study - 2 month(s) ago
Fecal immunochemical test could play an important role in surveillance for individuals with a family history of colorectal cancer. Ten-yearly colonoscopy and 2-yearly FIT between colonoscopies from ages 40 to 80 years was the optimal strategy.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
🔥 Hot paper from new investigators finds combining #colonoscopy with fecal immunochemical test can improve current familial #ColorectalCancer colonoscopy surveillance. 🔗 https://t.co/Trm3Qs92oQ https://t.co/rNveaLyJR7
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Mashup Score: 6Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study - 2 month(s) ago
Stool-based surveillance strategies were identified that may safely reduce the number of post-polypectomy surveillance colonoscopies. Multitarget stool DNA–based surveillance was more costly than colonoscopy surveillance, and fecal immunochemical test–based surveillance saved costs compared with colonoscopy surveillance.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
📰 News alert! A Gastroenterology article on stool-based testing for post-polypectomy #colorectalcancer surveillance was discussed in @physicianswkly last week. Check out both the study and article: Gastro 🔗 https://t.co/42zmAV8P7j Physician's Weekly 🔗 https://t.co/kQdHLBaOHq
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Mashup Score: 4
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with limited treatment options and a 5-year survival rate of just 12.8%.1 Early diagnosis is rare, leading to advanced disease and chemoresistance, which complicates treatment. Current chemotherapeutic regimens, including gemcitabine (GEM), nab-paclitaxel, 5-fluorouracil, oxaliplatin, irinotecan, and FOLFIRINOX, show modest efficacy.2 Novel therapies are urgently needed to improve outcomes and quality of life for PDAC patients.
Source: www.gastrojournal.orgCategories: General Medicine News, GastroenterologyTweet-
Research Letter finds dual targeting of syndecan-1 and glucose transporter-1 with a novel lipid-based delivery system enhances therapeutic efficacy and overcomes chemoresistance in #pancreatic ductal adenocarcinoma ➡️ https://t.co/YYc4qf1UTF https://t.co/d0hsURLCug
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🔔 Check out this CMGH study that reports a novel immunocompetent mouse model of chronic hepatitis B. ⭐ This model can be used for the efficacy assessment of developing immunotherapies 🔗 https://t.co/Uq06vcDnhZ https://t.co/Lf8cTzy9eS