Successful host defence against a pathogen can involve resistance or tolerance, with implications for prioritising either antimicrobial or immunomodulatory therapeutic approaches. Hyper-inflammation occurs in Covid-19 and is associated with worse outcomes. The efficacy of dexamethasone in preventing mortality in critical Covid-19 suggests that inflammation has a causal role in death. Whether this…
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Nature Medicine – A vision–language foundation model, trained on a dataset of more than 1 million echocardiogram video–text pairs, is able to assess various cardiac…
Nature – Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes,…
Machine learning–based EHR analysis could enable earlier diagnosis of an inborn error of immunity with heterogenous presentation.
Vaccination as a strategy to promote healthy aging is associated with challenges, opportunities, and implications for policy.
Nature – A body–brain circuit that regulates body inflammatory responses
Nature – Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes,…
Nature – Parental gut microbes boost offspring health and development of placenta.
Nature – Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline…
This cross-sectional study investigates the association between cardiometabolic disease prevalence in the US and deep learning–based assessment of the built environment from satellite imagery.
