To the Editor: Although many genes have polymorphisms, major histocompatibility complex genes are the most polymorphic. Many assume that the diversity of HLA increases the likelihood that a species can survive pandemics. Indeed, evidence suggests that HLA-B27 is protective for HIV1, hepatitis C2, and possibly influenza3. We recently reported results of a Web-based survey involving patients with…
Public health organizations advocate that people with osteoarthritis (OA) should engage in physical activity because it can improve their mental and physical well-being without worsening…
Objective To investigate the association of stair climbing difficulty and stair climbing frequency with the risk of all-cause mortality over 13 years in adults with…
Objective Using Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) juvenile idiopathic arthritis (JIA) registry data, we describe (1) clinical characteristics of patients with JIA transitioning…
Kaposi sarcoma (KS) is an angioproliferative neoplasm induced by human herpesvirus 8 (HHV8) targeting the cutaneous and lymphatic systems, with possible involvement of other organs…
Objective To compare cancer incidence, type, and survival between patients with idiopathic inflammatory myopathies (IIMs) in Western Australia (WA) and the general population. Methods Administrative…
Objective The World Trade Center (WTC) attack in New York resulted in a dust plume containing silica, hydrocarbons, and asbestos. Autoimmune disorders have been reported…
Objective To study changes in retention of first biologic disease-modifying antirheumatic drug (DMARD) therapy over a period of 15 years in an inception cohort of…
As the Chief Medical Officer for Highmark Inc. and having been on the health insurance side of medicine since 2008 while actively practicing rural family…
An evidence-based treatment approach is well supported in the literature for patients with osteoarthritis (OA). Physical therapists (PT) have clinical practice guidelines that clearly direct…
The public health burden of osteoarthritis (OA) is substantial as it is the most common form of arthritis, with an increase in prevalence over time.1…
