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Mashup Score: 16
Artificial intelligence has potential to counter vaccine hesitancy while building trust in vaccines, but it must be deployed ethically and responsibly, argue Heidi Larson and Leesa Lin Given the sluggish pace of traditional scientific approaches, artificial intelligence (AI), particularly generative AI, has emerged as a significant opportunity to tackle complex health challenges, including those in public health.1 Against this backdrop, interest has focused on whether AI has a role in bolstering public trust in vaccines and helping to minimise vaccine hesitancy, which the World Health Organization named as one of the top 10 global health threats.2 Vaccine hesitancy is a state of indecision before accepting or refusing a vaccination.3 It is a dynamic and context specific challenge that varies across time, place, and vaccine type. It is influenced by a range of factors, including sociocultural and political dynamics, as well as individual and group psychology. Its multifaceted and tempor
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 8Centring health workers and communities is key to building vaccine confidence online - 4 month(s) ago
Santi Indra Astuti and colleagues argue that whole-of-society efforts are needed to build an internet ecosystem that helps communities be resilient to future health misinformation challenges A local saying in Indonesia is that it is the most hoax filled country on Earth. As one of the world’s most diverse countries, with over 700 languages and people spread across 16 000 islands, it is challenging to reach its population with information that is credible and accurate. Misinformation has circulated in the country’s national media and affected discourse on everything from politics to natural disasters to immunisation for over a decade.12 Drawing from our experience with MAFINDO, a local civil society organisation dedicated to tackling misinformation and building health literacy within the community, we have learnt that promoting credible and compelling sources of health information benefits from taking a whole-of-society approach that helps to translate science for a general audience and
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 9
Objectives Risk of death after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has fallen during the pandemic, largely due to immunity fr…
Source: journals.sagepub.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 10Enterococcal Membrane Vesicles as Vaccine Candidates - 5 month(s) ago
Enterococcus faecium is a leading cause of nosocomial infections, particularly in immunocompromised patients. The rise of multidrug-resistant E. faecium, including Vancomycin-Resistant Enterococci (VRE), is a major concern. Vaccines are promising alternatives to antibiotics, but there is currently no vaccine available against enterococci. In a previous study, we identified six protein vaccine candidates associated with extracellular membrane vesicles (MVs) produced by nosocomial E. faecium. In this study, we immunized rabbits with two different VRE-derived MV preparations and characterized the resulting immune sera. Both anti-MV sera exhibited high immunoreactivity towards the homologous strain, three additional VRE strains, and eight different unrelated E. faecium strains representing different sequence types (STs). Additionally, we demonstrated that the two anti-MV sera were able to mediate opsonophagocytic killing of not only the homologous strain but also three unrelated heterologo
Source: www.mdpi.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 8Is the US’s Vaccine Adverse Event Reporting System broken? - 6 month(s) ago
A BMJ investigation has raised concerns that the VAERS system isn’t operating as intended and that signals are being missed. Jennifer Block reports Three weeks after receiving a second dose of a covid vaccine, Robert Sullivan collapsed at home on his treadmill. An anaesthesiologist in Maryland, USA, he was a particularly fit 49 year old: the week before falling ill, he’d been happily skiing at altitude in Colorado. Sullivan was given a diagnosis of sudden onset pulmonary hypertension, which is generally progressive, can be fatal, and in most cases can’t be cured. The condition is rare, especially in middle aged men. Sullivan decided to file a report in the Vaccine Adverse Event Reporting System (VAERS), which collects reports of symptoms, diagnoses, hospital admissions, and deaths after vaccination for the purpose of capturing post-market safety signals. But the submission process was a glitchy race against the clock. “The format is cumbersome and it times you out,” he tells The BMJ .
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 8Is the US’s Vaccine Adverse Event Reporting System broken? - 6 month(s) ago
A BMJ investigation has raised concerns that the VAERS system isn’t operating as intended and that signals are being missed. Jennifer Block reports Three weeks after receiving a second dose of a covid vaccine, Robert Sullivan collapsed at home on his treadmill. An anaesthesiologist in Maryland, USA, he was a particularly fit 49 year old: the week before falling ill, he’d been happily skiing at altitude in Colorado. Sullivan was given a diagnosis of sudden onset pulmonary hypertension, which is generally progressive, can be fatal, and in most cases can’t be cured. The condition is rare, especially in middle aged men. Sullivan decided to file a report in the Vaccine Adverse Event Reporting System (VAERS), which collects reports of symptoms, diagnoses, hospital admissions, and deaths after vaccination for the purpose of capturing post-market safety signals. But the submission process was a glitchy race against the clock. “The format is cumbersome and it times you out,” he tells The BMJ .
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 8Is the US’s Vaccine Adverse Event Reporting System broken? - 6 month(s) ago
A BMJ investigation has raised concerns that the VAERS system isn’t operating as intended and that signals are being missed. Jennifer Block reports Three weeks after receiving a second dose of a covid vaccine, Robert Sullivan collapsed at home on his treadmill. An anaesthesiologist in Maryland, USA, he was a particularly fit 49 year old: the week before falling ill, he’d been happily skiing at altitude in Colorado. Sullivan was given a diagnosis of sudden onset pulmonary hypertension, which is generally progressive, can be fatal, and in most cases can’t be cured. The condition is rare, especially in middle aged men. Sullivan decided to file a report in the Vaccine Adverse Event Reporting System (VAERS), which collects reports of symptoms, diagnoses, hospital admissions, and deaths after vaccination for the purpose of capturing post-market safety signals. But the submission process was a glitchy race against the clock. “The format is cumbersome and it times you out,” he tells The BMJ .
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 8Is the US’s Vaccine Adverse Event Reporting System broken? - 6 month(s) ago
A BMJ investigation has raised concerns that the VAERS system isn’t operating as intended and that signals are being missed. Jennifer Block reports Three weeks after receiving a second dose of a covid vaccine, Robert Sullivan collapsed at home on his treadmill. An anaesthesiologist in Maryland, USA, he was a particularly fit 49 year old: the week before falling ill, he’d been happily skiing at altitude in Colorado. Sullivan was given a diagnosis of sudden onset pulmonary hypertension, which is generally progressive, can be fatal, and in most cases can’t be cured. The condition is rare, especially in middle aged men. Sullivan decided to file a report in the Vaccine Adverse Event Reporting System (VAERS), which collects reports of symptoms, diagnoses, hospital admissions, and deaths after vaccination for the purpose of capturing post-market safety signals. But the submission process was a glitchy race against the clock. “The format is cumbersome and it times you out,” he tells The BMJ .
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Effectiveness of the live zoster vaccine during the 10 years following vaccination: real world cohort study using electronic health records - 6 month(s) ago
Objectives To assess the effectiveness of live zoster vaccine during more than 10 years after vaccination; and to describe methods for ascertaining vaccine effectiveness in the context of waning. Design Real world cohort study using electronic health records. Setting Kaiser Permanente Northern California, an integrated healthcare delivery system in the US, 1 January 2007 to 31 December 2018. Population More than 1.5 million people aged 50 years and older followed for almost 9.4 million person years. Main outcome measure Vaccine effectiveness in preventing herpes zoster, postherpetic neuralgia, herpes zoster ophthalmicus, and admission to hospital for herpes zoster was assessed. Change in vaccine effectiveness by time since vaccination was examined using Cox regression with a calendar timeline. Time varying indicators were specified for each interval of time since vaccination (30 days to less than one year, one to less than two years, etc) and adjusted for covariates. Results Of 1 505 6
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Effectiveness of the live zoster vaccine during the 10 years following vaccination: real world cohort study using electronic health records - 6 month(s) ago
Objectives To assess the effectiveness of live zoster vaccine during more than 10 years after vaccination; and to describe methods for ascertaining vaccine effectiveness in the context of waning. Design Real world cohort study using electronic health records. Setting Kaiser Permanente Northern California, an integrated healthcare delivery system in the US, 1 January 2007 to 31 December 2018. Population More than 1.5 million people aged 50 years and older followed for almost 9.4 million person years. Main outcome measure Vaccine effectiveness in preventing herpes zoster, postherpetic neuralgia, herpes zoster ophthalmicus, and admission to hospital for herpes zoster was assessed. Change in vaccine effectiveness by time since vaccination was examined using Cox regression with a calendar timeline. Time varying indicators were specified for each interval of time since vaccination (30 days to less than one year, one to less than two years, etc) and adjusted for covariates. Results Of 1 505 6
Source: www.bmj.comCategories: General Medicine News, General HCPsTweet
Artificial intelligence has potential to counter #vaccine hesitancy, while building trust in vaccines, but must be balanced with ethical deployment, argue @ProfHeidiLarson & Leesa Lin of @vaccine_trust @LSHTM Read more in our new Collection https://t.co/AWhWGufeAB