• Mashup Score: 0

    This cohort study of older adults without diabetes compares different prediabetes definitions and characterizes the risks of prediabetes and diabetes in this population.

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    • @kaulcsmc @AmarPut @kamleshkhunti @DLBHATTMD @ProfKausikRay @hvanspall @SantosGallegoMD @mmamas1973 @amibanerjee1 @DrDerekConnolly @AliceYYCheng @docwas @GoggleDocs In #ARIC (mean age 76y), 9% progressed to T2D during 6.5y f/u https://t.co/L06FJTyAea In #UKBiobank (mean age 56y), 14% progressed to T2D during 11y f/u. However, vast majority developed incident CV or kidney event without progression to T2D. @mchonig https://t.co/ednxWHvN4d https://t.co/mmbx9Dymmu

  • Mashup Score: 0

    Context A sex discordance in COVID exists, with males disproportionately affected. Although sex steroids may play a role in this discordance, no definitive genetic data exist to support androgen-mediated immune suppression for viral susceptibility, nor for adrenally produced androgens. Objective The common adrenal-permissive missense-encoding variant HSD3B1(1245C) that enables androgen synthesis…

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    • 10/10 This was all led by Jeff McManus and his incredible effort! I also want to thank @WiebkeArlt, EIC at @EJEndo for interest and publishing our study! https://t.co/9emIExxYFL

    • 1/10 Delighted that our story led by Jeff McManus on #HSD3B1 inheritance and female #COVID susceptibility @uk_biobank #UKBioBank is out @EJEndo! Data suggest an age-dependent androgen effect on susceptibility. A 🧵 https://t.co/9emIExxqQd

  • Mashup Score: 2

    “Just Accepted” papers have undergone full peer review and have been accepted for publication in Radiology: Artificial Intelligence. This article will undergo copyediting, layout, and proof review before it is published in its final version. Please note that during production of the final copyedited article, errors may be discovered which could affect the content. UK Biobank (UKB) has recruited…

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    • RT @Radiology_AI: Experimental inference engine automates analysis of body MRI in #UKBiobank https://t.co/yV4Yq0ZfWk @UU_University @uk_bio…

  • Mashup Score: 4

    Background: Rare sequence variation in genes underlying cardiac repolarization and common polygenic variation influence QT interval duration. However, current clinical genetic testing of individuals

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    • #OriginalResearch: Genomic analysis from #UKBiobank and #TOPMed elucidates the monogenic and polygenic contributions to QTc prolongation @EmeliaBenjamin @patrick_ellinor @BrandonFornwalt @alonso_epi @ChrisMHaggerty @nauffal_victor @steven_lubitz https://t.co/6ASE0jDfzO https://t.co/QZQJC4ETLX

  • Mashup Score: 2
    Retinal Retirement - 2 year(s) ago

    Can the gap between retina age and real age be used as an evaluation of patients’ risk of death?

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    • Can the gap between #retina age and real age be used as an evaluation of patients’ risk of death? #retinalagegap #OphthoTwitter #ophthalmology #UKBiobank #Biobank #AI #artificialintelligence https://t.co/V4IYIZA8IN