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Mashup Score: 0
Efficacy, Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease – Full Text View.
Source: clinicaltrials.govCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2
Our analysis suggests that in people with type 2 diabetes and high cardiovascular risk, tirzepatide slowed the rate of eGFR decline and reduced UACR in clinically meaningful ways compared with insulin glargine.
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 7
This editorial refers to ‘Albuminuria as a marker of systemic congestion in patients with heart failure’ by E.M. Boorsma, et al., https://doi.org/10.1093/eurhea
Source: OUP AcademicCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Association of Empagliflozin Treatment With Albuminuria Levels in Patients With Heart Failure - 1 year(s) ago
This post hoc analysis of a randomized clinical trial of patients with heart failure evaluates the association of empagliflozin with albuminuria levels in study participants.
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet-
While #UACR clearly identifies higher risk pts, CV & kidney benefits in patients w HF appear present even in those without albuminuria CVd +HFH HR 0.80 (0.69-0.92) for UACR<30 subgroup in #EMPERORPooled Also prevents progression to new macroalbuminuria! https://t.co/E0qk7O67Zz https://t.co/OWVopb2rsl https://t.co/6A9WR7cKeO
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Mashup Score: 0Cardiovascular Effects of Canagliflozin in Relation to Renal Function and Albuminuria: - 2 year(s) ago
Abstract Background People with type 2 diabetes mellitus (T2DM) have elevated cardiovascular (CV) risk, including for hospitalization for heart failure (HHF). Canagliflozin reduced CV and kidney ev…
Categories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2Finerenone and Heart Failure Outcomes by Kidney Function/Albuminuria in Chronic Kidney Disease and Diabetes: - 2 year(s) ago
Abstract Background In patients with type 2 diabetes (T2D), risks of cardiovascular mortality and heart failure (HF) increase with decreasing kidney function (estimated glomerular filtration rate […
Source: JACC: Heart FailureCategories: Cardiologists, Latest HeadlinesTweet-
#Finerenone and #HeartFailure Outcomes by Kidney Function/Albuminuria in #CKD and DM This subgroup analyses by baseline #eGFR and/or #UACR categories show consistent benefits of #finerenone to ⬇️ the incidence of HF events https://t.co/7MCjiaDNRO @JACCJournals @AgarwalRajivMD https://t.co/uizTg4CpDt
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Mashup Score: 0
Our analysis suggests that in people with type 2 diabetes and high cardiovascular risk, tirzepatide slowed the rate of eGFR decline and reduced UACR in clinically meaningful ways compared with insulin glargine.
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 3
In this randomized crossover clinical trial in patients with CKD with and without type 2 diabetes, we assessed the albuminuria-lowering effect of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin and mineralocorticoid receptor antagonist (MRA) eplerenone individually and in combination. We demonstrated that the albuminuria-lowering effects of dapagliflozin and eplerenone alone…
Source: American Society of NephrologyCategories: Cardiologists, Latest HeadlinesTweet-
Albuminuria-Lowering Effect of #Dapagliflozin, #Eplerenone, and their Combination in Patients with #CKD Combining #dapagliflozin with #eplerenone resulted in a robust additive #UACR-lowering effect. #Flozinators https://t.co/VhS7KBbOoz @JASN_News @BSHeartFailure @AndrewJSauer https://t.co/pYw2O6t2ps
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@AndrewJSauer @hvanspall @kamleshkhunti @JavedButler1 @mmamas1973 @AnastasiaSMihai @AmarPut @AskDrShashank @ACCinTouch @escardio @ABCDiab @EASDelearning @gcfmd P2 #MIRACLE trial of new MR modulator balcinrenone is doing just that! #UACR ≥30 mg/g (3 mg/mmol) key inclusion criteria. Adds complexity to applying to global P3 setting as @hvanspall stated though https://t.co/qAFBZgN5Uw