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Mashup Score: 1Definitive weekly hypofractionated radiotherapy in surgery-ineligible older adults with cutaneous squamous cell carcinoma of the head and neck region - 8 month(s) ago
This study intends to address the impact of weekly hypofractionated radiation therapy with curative intent for cutaneous squamous cell carcinoma of the head and neck region in the elderly population.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Due to the improved overall survival and life expectancy of older women with breast cancer, cardiovascular disease (CVD) arose as the primary cause of non-cancer-related deaths in this population. Therefore, assessing the health-related quality of life (HRQoL) of breast cancer patients with comorbid CVD is becoming increasingly vital. Our study aimed to evaluate the association between comorbid CVD and HRQoL among older women with early-stage breast cancer who are receiving adjuvant endocrine therapy (AET) in the United States.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Association of cardiovascular disease with health-related quality of life among older women with early-stage breast cancer undergoing adjuvant endocrine therapy https://t.co/ftKUHXab1X @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #HRQoL https://t.co/MmeWfgyvDH
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Mashup Score: 0Development and testing of the Outcome Prioritization Tool adjusted to older patients with cancer: A pilot study - 8 month(s) ago
In older patients with cancer, the balance between harms and benefits of treatment is delicate. There is a higher risk of adverse outcomes of cancer treatment due to comorbidity and geriatric impairments, while clinical benefit is uncertain due to their frequent exclusion in clinical trials [1,2]. Potential benefits of treatment (for example, increased survival) may come at a cost (for example, increased treatment side-effects or loss of function). As a result, treatment decisions are often preference sensitive, which means that the optimal treatment choice depends on a patient’s personal values and priorities [3].
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Geriatric assessment and management (GAM) is recommended by professional organizations and recently several randomized controlled trials (RCTs) demonstrated benefits in multiple health outcomes. GAM typically leads to one or more recommendations for the older adult on how to optimize their health. However, little is known about how well recommendations are adhered to. Understanding these issues is vital to designing GAM trials and clinical programs. Therefore, the aim of this study was to examine the number of GAM recommendations made and adherence to and satisfaction with the intervention in a multicentre RCT of GAM for older adults with cancer.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
As the population is ageing, the number of older patients with multimorbidity including cancer continues to increase. To improve care for these patients, the European Union-funded project “Streamlined Geriatric and Oncological evaluation based on IC Technology” (GERONTE) was initiated to develop a new, patient-centred, holistic care pathway. The aim of this paper is to analyse what challenges are encountered in everyday clinical practice according to patients, their informal caregivers, and healthcare professionals as a starting point for the development of the care pathway.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review - 9 month(s) ago
Blood biomarkers are potentially useful prognostic markers and may support treatment decisions, but it is unknown if and which biomarkers are most useful in older patients with solid tumors. The aim of this systematic review was to evaluate the evidence on the association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Older adults represent a large segment of the oncology population, however, they remain underrepresented in clinical research. Treatment of older adults is often extrapolated using data from younger and fitter patients, which may not be appropriate. Furthermore the implications of toxicity from treatment can be greater for this population. Predicting toxicity from treatment and its effect on quality of life and functional status for older adults therefore is important.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Assessment of an embedded primary care-derived electronic health record (EHR) frailty index (eFI) in older adults with acute myeloid leukemia - 9 month(s) ago
Assessing frailty is integral to treatment decision-making for older adults with acute myeloid leukemia (AML). Prior electronic frailty indices (eFI) derive from an accumulated-deficit model and are associated with mortality in older primary care populations. We evaluated use of an embedded eFI in AML by describing baseline eFI categories by treatment type and exploring associations between eFI categories, survival, and treatment received.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Preoperative low handgrip strength (HGS) with HGS asymmetry is associated with adverse outcomes among older adults with gastric cancer - 9 month(s) ago
This study aimed to explore the associations of low hand grip strength (HGS), HGS asymmetry, their combinations, and frailty on hospital readmissions, total complications, and prolonged length of stay (PLOS) among older adults with gastric cancer.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Preoperative low handgrip strength (HGS) with HGS asymmetry is associated with adverse outcomes among older adults with gastric cancer https://t.co/Zm3WoBMAWo @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #HandgripStrength #HGS #Frailty https://t.co/XVOtWmnjdj
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Mashup Score: 0
Patients with hematologic malignancies often require intensive and complex treatment regimens that result in substantial toxicities. They also face significant illness burden and health care utilization making social support critical to optimizing their outcomes [1,2]. Older adults with hematologic malignancies are arguably even more vulnerable, given their higher risk of treatment toxicity due to concurrent cytopenias and associated functional limitations requiring extensive social support.
Source: www.geriatriconcology.netCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Definitive weekly hypofractionated radiotherapy in surgery-ineligible older adults with cutaneous squamous cell carcinoma of the head and neck region https://t.co/OBXIxMDxlM @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #RadiationTherapy