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Mashup Score: 16From healthy aging to complex needs in older adults: Onco-geriatric insights from the EuGMS 2024 conference, a report from Young SIOG - 17 hour(s) ago
Comprehensive geriatric assessment (CGA) has become a crucial tool in the management of older adults with cancer. Several randomized controlled trials have demonstrated improved outcomes with integration of CGA, including improved treatment completion rates [1], decreased treatment-related toxicities [1–3], improved quality of life [1,4] (QoL), and improved treatment tolerability [1–3]. Thus, several guidelines and positions papers have recently emphasized the need for routine CGA to improve outcomes and guide treatment decisions for older patients with cancer [5–8].
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 18Systematic review of nutrition interventions in older patients with cancer: A synthesis of evidence and a future research priority - 3 day(s) ago
Older patients with cancer (65 years and older) are a growing population with unique nutrition-and treatment-related issues that accelerate aging. Nutrition interventions attenuate nutritional decline, muscle loss, and risk of malnutrition and sarcopenia in patients with cancer, however the evidence for older patients with cancer is limited. The aim of this systematic review was to evaluate the efficacy of nutrition interventions on nutritional status, body weight/composition and clinical outcomes in older patients with cancer and to identify future research priority areas.
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet-
Systematic review of nutrition interventions in older patients with cancer: A synthesis of evidence and a future research priority https://t.co/f031G61R6y @WilliamDale_MD @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier #Nutritio #Malnutrition #Sarcopenia https://t.co/8ChFZxFDb0
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Mashup Score: 4
In the biomedical field, including in geriatric oncology, many papers study the association of a factor X with an outcome Y, usually adjusted on several covariates. Researchers in geriatric oncology, for example, are commonly interested in how frailty is associated with a range of outcomes, including (but not limited to) overall survival, treatment receipt, complications, quality of life, and functional status (Table 1). With the growing availability of and access to so-called real-world data, it has become easy to investigate nearly any association between two variables in vast datasets.
Source: www.geriatriconcology.netCategories: General Medicine News, Hem/OncsTweet-
RT @JGeriOnc: Moving beyond studying mere association: A methodological perspective https://t.co/t7OFTIfRIW @SPilleron @WilliamDale_MD @myC…
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Mashup Score: 4Addressing educational gaps in geriatric oncology: Insights from medical oncologists - 13 day(s) ago
Most patients with cancer are 65 years or older and account for 65 % of newly diagnosed cases in Canada [1]. Older adults with cancer are more likely to experience frailty and other geriatric syndromes such as falls, cognitive impairment, and depression [2]. This population also experiences more side effects from anti-cancer therapies leading to early treatment discontinuation and reduced quality of life [3]. Specialized care focused on identifying and addressing age-associated factors is required to improve outcomes for older adults with cancer.
Source: www.geriatriconcology.netCategories: General Medicine News, Hem/OncsTweet-
RT @JGeriOnc: Addressing educational gaps in geriatric oncology: Insights from medical oncologists https://t.co/QnjTZ0PcHm @WilliamDale_MD…
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Mashup Score: 9
Diffuse large B-cell lymphoma (DLBCL) is the most common type of B-cell lymphoma, predominantly afflicting older adults. There remains a notable absence of data regarding DLBCL in older adults in Latin America.
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet-
Real-world data on the clinical features, therapy patterns, and outcomes of older adults with diffuse large B-cell lymphoma in Latin America: A study from the Grupo de Estudio Latinoamericano de Linfoproliferativos (GELL) https://t.co/VNxbgaq3cI @WilliamDale_MD @myCARG #GeriOnc https://t.co/i5Z9xKHwVK
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Mashup Score: 5
Multiple myeloma (MM) accounts for 19 % of hematologic malignancies diagnosed in the United States and has a higher incidence in older adults [1]. Treatment decision-making for older adults with MM is complicated by a greater prevalence of comorbid conditions and functional impairment associated with advancing age [2,3]. Biomarkers of aging have drawn attention as a means to better understand aging and its effects on older adults with cancer. The gene p16INK4a (p16) codes for a protein that blocks cyclin-dependent kinase, and greater expression is associated with cellular senescence [4].
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet-
Association of p16(INK4a), a biomarker of cellular senescence, with receipt of therapy and frailty status among adults with plasma cell disorders https://t.co/LGrBohMp9h @ChrisJensenMD @WilliamDale_MD @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG https://t.co/H3f5cNZpBR
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Mashup Score: 6Designing observational studies to estimate treatment effects in geriatric oncology: A closer look at confounding and its mitigation - 22 day(s) ago
Adults aged 70 or over account for more than a third of all new cancer diagnoses globally [1]. Despite continuous efforts in the last decades, the inclusion rate of older adults with cancer in clinical trials is still low [2]. In addition, many cancer treatment trials tend to enroll young, healthy patients due to use of strict eligibility criteria [3]. However, in clinical practice, patients are often older, sicker, and have poorer performance status [4], thus limiting the generalizability of clinical trial results to patients seen in clinics.
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet-
Designing observational studies to estimate treatment effects in geriatric oncology: A closer look at confounding and its mitigation https://t.co/U1cBRxsL7k @SPilleron @LundJenny @WilliamDale_MD @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier https://t.co/7CtIOLjwWt
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Mashup Score: 8Potential drug-drug interactions between cancer therapies and active antiretroviral treatments among Medicare-enrolled patients with cancer and HIV - 2 month(s) ago
In the United States (US), cancer is a leading cause of non-AIDS death among people living with HIV (PWH) [1]. Although cancer contributes significantly to morbidity and mortality among PWH, adults with HIV are less likely to receive curative cancer treatment compared to cancer patients without HIV with the same type and stage of cancer [2,3]. One important factor that impacts cancer treatment decisions is physician knowledge and perceptions. Oncologists may choose to withhold treatment from PWH with cancer due to a lack of information about appropriate treatment paradigms.
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet-
Potential drug-drug interactions between cancer therapies and active antiretroviral treatments among Medicare-enrolled patients with cancer and HIV https://t.co/6usErhKk4I @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier https://t.co/NvoFoXfgiF
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Mashup Score: 4Emotional impact of cancer from a patient's perspective - 2 month(s) ago
Your work in geriatric oncology places you in a unique position to help people in the most significant way possible–to literally save their lives. Such a duty of care is profound, perhaps even more so when you face the most vulnerable patients– including children, the underprivileged, or those diminished by prior illness or the aging process itself.
Source: www.geriatriconcology.netCategories: General Medicine News, Hem/OncsTweet-
RT @JGeriOnc: Emotional impact of cancer from a patient's perspective https://t.co/gEknMeCFMU @WilliamDale_MD @rochgerionc @myCARG #GeriOnc…
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Mashup Score: 15The effect of lifestyle interventions on sarcopenia in advanced colorectal cancer: A systematic review - 2 month(s) ago
Sarcopenia is a common syndrome in older patients with advanced colorectal cancer that is worsened during standard-of-care chemotherapy and is associated with increased chemotherapy toxicity, impaired quality of life, and poorer survival independent of cancer stage or chemotherapy response. Physical activity and nutrition interventions have been shown to support muscle mass in patients recovering from treatment for early-stage colorectal cancer. The aim of this present review was to evaluate the effect of physical activity and nutritional interventions on sarcopenia in patients with advanced colorectal cancer.
Source: www.geriatriconcology.netCategories: General Medicine News, Oncologists1Tweet-
The effect of lifestyle interventions on sarcopenia in advanced colorectal cancer: A systematic review https://t.co/9VblNFQNNB @WilliamDale_MD @rochgerionc @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier #Sarcopenia #ColorectalCancer #Lifestyle https://t.co/1QeWkisULb
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From healthy aging to complex needs in older adults: Onco-geriatric insights from the EuGMS 2024 conference, a report from Young SIOG https://t.co/udivxu0qZ5 @WilliamDale_MD @myCARG #GeriOnc #OlderAdults #OncoAlert #SIOG #YoungSIOG #Elsevier #Resilience #Frailty