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Mashup Score: 2Epitope-Based IgE Assays and Their Role in Providing Diagnosis and Prognosis of Food Allergy - 7 month(s) ago
With advances in molecular and computational science, epitope-specific IgE antibody profiling has been developed and recently brought into clinical practice. Epitope-based testing detects IgE antibodies that directly bind to antigenic sites of an allergen, providing increased resolution specificity and fewer false-positive results for diagnosing food allergy. Epitope-binding profiles may also serve as prognostic markers of food allergy and help predict quantities of allergen that would provoke a reaction (ie, eliciting dose, possible severity of a reaction after allergen ingestion, and outcomes of treatment options such as oral immunotherapy [OIT]).
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder that manifests as lung and/or liver disease. As symptoms of AATD overlap with those of common pulmonary and hepatic conditions, AATD is often misdiagnosed, which has resulted in substantial underdiagnosis of AATD worldwide. Although screening patients for AATD is recommended, the lack of procedures to facilitate testing remains a barrier to accurate diagnosis of AATD. Delays in AATD diagnosis can worsen outcomes for patients by postponing appropriate disease-modifying treatments.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Significance and Potential Role of Eosinophils in Non-Cystic Fibrosis Bronchiectasis - 1 year(s) ago
Bronchiectasis is a complex and heterogeneous disease with a myriad of pulmonary and extrapulmonary etiologies. Bronchiectasis has a predominantly neutrophilic inflammatory profile. However, eosinophilic inflammation has also been documented in both the airways and the systemic circulation. Various diseases (eg, asthma, allergic bronchopulmonary aspergillosis, chronic rhinosinusitis with nasal…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0
BackgroundPulmonary hypertension (PH) is a lethal disease characterized by pulmonary vascular remodeling, which is mediated by the abnormal proliferation/migration of pulmonary arterial smooth muscle cells (PASMCs). Recent reports suggest the involvement of histone acetylation in PAH development and that histone deacetylase (HDAC) inhibitors have therapeutic potential for the treatment of PAH….
Source: FrontiersCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 2Significance and potential role of eosinophils in non-cystic fibrosis bronchiectasis - 2 year(s) ago
Bronchiectasis is a complex and heterogeneous disease caused by a myriad of pulmonary and extrapulmonary aetiologies. Bronchiectasis has a predominantly neutrophilic inflammatory profile, however, eosinophilic inflammation has also been documented in both the airways and systemic circulation. Various diseases (e.g. asthma, allergic bronchopulmonary aspergillosis, chronic rhinosinusitis with nasal…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0The Role of Systemic Therapies in Head & Neck Sarcomas - 2 year(s) ago
Herbert LOONGThe Chinese University of Hong Kong, Hong KongHead & Neck sarcomas are rare, accounting for about 1% of Head & Neck malignancies and 5% of sarco…
Source: YouTubeCategories: Latest Headlines, Oncologists2Tweet
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Mashup Score: 4ACL Injuries | Knee Injuries | Dr. Christopher Ahmad - 3 year(s) ago
One of the more serious knee injuries an athlete can sustain is a tear of the anterior cruciate ligament, more commonly known as ACL injuries.
Source: Dr. Christopher S AhmadCategories: Latest Headlines, OrthopedicsTweet-
⭐️👉 The way in which the #ACL #tears plays a #role in our #approach to #surgical #intervention... https://t.co/eS7TOhonmZ BOOK APPOINTMENT: https://t.co/7lj3kLVlCf #knee #injury #options #treatment #sportsmedicine #sportsperformance #thebest @OrthoColumbia @nyphospital @NYCFC https://t.co/LGQRclVCPc
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Mashup Score: 1
Primary sclerosing cholangitis (PSC) is a common indication for liver transplantation (LT). Up to 25% of patients experience recurrence of PSC (rPSC) after LT, which is associated with significant mo…
Source: Wiley Online LibraryCategories: Latest Headlines, TransplantationTweet
In Current Issue! #Epitope-Based #IgE #Assays and Their #Role in Providing #Diagnosis and #Prognosis of #Food #Allergy https://t.co/15xaJ03qbQ https://t.co/xEpk7qSlzn