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Mashup Score: 0
Objectives To evaluate the safety and immunogenicity of third and fourth BNT162b2 boosters in patients with SLE and rheumatoid arthritis (RA). Methods Patients with SLE and RA aged 18–65 years who completed a series of inactivated, adenoviral vector, or heterogenous adenoviral vector/mRNA vaccines for at least 28 days were enrolled. Immunogenicity assessment was done before and day 15 after each…
Source: Lupus Science & MedicineCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0
Objectives To evaluate the safety and immunogenicity of third and fourth BNT162b2 boosters in patients with SLE and rheumatoid arthritis (RA). Methods Patients with SLE and RA aged 18–65 years who completed a series of inactivated, adenoviral vector, or heterogenous adenoviral vector/mRNA vaccines for at least 28 days were enrolled. Immunogenicity assessment was done before and day 15 after each…
Source: Lupus Science & MedicineCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Reply to: Heart Rate Response in OSA: A Clue to Reveal Cardiovascular Benefit from CPAP? - PubMed - 2 year(s) ago
Reply to: Heart Rate Response in OSA: A Clue to Reveal Cardiovascular Benefit from CPAP?
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 4
Response criteria for paediatric intracranial ependymoma vary historically and across different international cooperative groups. The Response Assessment in the Pediatric Neuro-Oncology (RAPNO) working group, consisting of an international panel of paediatric and adult neuro-oncologists, neuro-radiologists, radiation oncologists, and neurosurgeons, was established to address both the issues and…
Source: The Lancet OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Homogeneous and common objective disease assessments and standardised response criteria are important for better international clinical trials for CNS germ cell tumours. Currently, European protocols differ from those of North America (the USA and Canada) in terms of criteria to assess radiological disease response. An international working group of the European Society for Paediatric Oncology…
Source: The Lancet OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Dupilumab Demonstrates Rapid Onset of Response Across Three Type 2 Inflammatory Diseases - 2 year(s) ago
Type 2 inflammatory diseases often co-exist in patients. Dupilumab targets type 2 inflammation and has demonstrated treatment benefits in patients with atopic dermatitis (AD), asthma, and chronic rhinosinusitis with nasal polyps (CRSwNP) with an acceptable safety profile.
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Effective anti-SARS-CoV-2 immune response in patients with clonal mast cell disorders. - 2 year(s) ago
Mast cells are key players in innate immunity and the Th2 adaptive immune response. The latter counterbalances the Th1 response, which is critical for antiviral immunity. Clonal mast cell activation disorders (cMCADs, such as mastocytosis and clonal mast cell activation syndrome) are characterized by abnormal mast cell accumulation and/or activation. No data on the antiviral immune response in…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 2
Clinical Research Information Service of Korea National Institute of Health (CRIS), KCT0005533.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0The Heterogeneity of Inflammatory Response and Emphysema in Chronic Obstructive Pulmonary Disease - PubMed - 2 year(s) ago
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by chronic inflammation, emphysema, airway remodeling, and altered lung function. Despite the canonical classification of COPD as a neutrophilic disease, blood and airway eosinophilia are found in COPD patients. Id …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 1Pharmaco-Metabolomics of Inhaled Corticosteroid Response in Individuals with Asthma - PubMed - 2 year(s) ago
Metabolomic indicators of asthma treatment responses have yet to be identified. In this study, we aimed to uncover plasma metabolomic profiles associated with asthma exacerbations while on inhaled corticosteroid (ICS) treatment. We determined whether these profiles change with age from adolescence t …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
#Epidemiology This week on LSM: Third #BNT162b2 #booster significantly improved #humoral & #cellular #immunogenicity in patients with #SLE & #RA. The #benefit of a short-interval fourth booster in #patients with #suboptimal #humoral #response was unclear https://t.co/A67fzCDgEg