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Mashup Score: 23
Blocking BDNF-driven synaptic plasticity extends survival in patient-derived glioma xenograft models.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 17
Minority mitochondrial outer membrane permeabilization (miMOMP) during senescence drives the SASP.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 10
Tumoral Lactobacillus iners predicts poor chemoradiation response and decreased survival in cervical cancer.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 10Arginine Promotes Metabolic Reprogramming and Liver Tumorigenesis - 7 month(s) ago
Arginine is high in hepatocellular carcinoma and promotes tumorigenesis by altering metabolic gene expression.
Source: aacrjournals.orgCategories: General Medicine News, Onc News and JournalsTweet
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Mashup Score: 0
CRISPR–Cas9 gene editing in T cells can lead to partial or complete loss of the targeted chromosome.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 4Astrocyte–Tumor Cell Cross-talk Promotes Brain Metastasis of Small Cell Lung Cancer - 7 month(s) ago
Small cell lung cancer (SCLC) cell–astrocyte cross-talk drives a brain development program and SCLC growth.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Hyperactivation of Oncogenic Pathways Hinders Cancer Cell Survival - 7 month(s) ago
Gain-of-function screens reveal the context-specific lethality of oncogenic pathway activation.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1
Brain tumor–associated neutrophils (TAN) exhibit unique myeloid cell–induced protumor phenotypes.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 6Multicellular Spatial Organization Determines Immunotherapy Response - 8 month(s) ago
Cellular composition and spatial organization can predict immunotherapy response in triple-negative breast cancer.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Chronic Inflammation Drives TP53-Mutant Leukemic Evolution - 8 month(s) ago
Chronic inflammation enhances the fitness advantage of TP53-mutant cells and promotes genetic evolution.
Source: aacrjournals.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Read Cancer Discovery's #ResearchWatch: Chronic Inflammation Drives TP53-Mutant #Leukemic Evolution, a summary of the paper by @AlbaRMeira, @RuggieroNorfo, @Sean_wen221, Agathe Chédeville, @IleanaAntony, @AdamMead_Oxford et al. https://t.co/krS2zs2qxk @OxfordHaem @GustaveRoussy https://t.co/WVSWKmRrUy
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Read this week's Cancer Discovery #ResearchWatch: Gliomas Hijack Adaptive Plasticity to Strengthen Neuron–Tumor Synapses, a summary of the paper by @Kathryn_RTaylor, @michelle_monje et al. https://t.co/TQ5INhXL1n @Stanford @HHMInew @CancerNeurosci https://t.co/b53Zr0f3ZH