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Mashup Score: 1Increased exercise tolerance in humanized G6PD-deficient mice - 8 hour(s) ago
Key PointsG6PD-deficient mice maintain higher exercise speeds without increased red blood cell hemolysis, questioning assumed risks.Increased cardiac outpu
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 27The hepcidin-ferroportin axis modulates liver endothelial cell BMP expression to influence iron homeostasis in mice - 1 day(s) ago
Key PointsLiver endothelial cell (LEC) ferroportin modulates cellular iron and BMP ligand expression to influence hepcidin and systemic iron levels.Hepcidi
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
Hepcidin regulates LEC ferroportin, suggesting bidirectional cross talk between LECs and hepatocytes to fine-tune systemic iron homeostasis. https://t.co/DZXbJ4QsHd #redcellsironanderythropoiesis https://t.co/JGhpqDdiPI
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Mashup Score: 21How to prioritize between oxygen and iron - 3 day(s) ago
In this issue of Blood, Zhang et al introduce a new dimension to the intricate interplay between sensing mechanisms for oxygen and iron. They show how diff
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
How to prioritize between oxygen and iron https://t.co/Qp1jvb0lT4 #redcellsironanderythropoiesis https://t.co/5L7FS1WgWS
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Mashup Score: 5A bulge uridine in the HIF2α IRE allows IRP1 but not IRP2 to selectively regulate HIF2α expression and ensuing EPO levels - 8 day(s) ago
Key PointsA bulge uridine in HIF2α IRE allows IRP1 but not IRP2 to repress HIF2α expression, regulating EPO synthesis and red blood cell production.IRP2 de
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
A bulge uridine in HIF2α IRE allows IRP1 but not IRP2 to repress HIF2α expression, regulating EPO synthesis and red blood cell production. https://t.co/4GUkzzu2fy #redcellsironanderythropoiesis https://t.co/M30bpinuUp
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Mashup Score: 20B-1 B cells lose self-control in SCD - 22 day(s) ago
In this issue of Blood, Su et al report that patients with sickle cell disease (SCD) have elevated quantities of a subset of B cells (B-1 cells), which sig
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
B-1 B cells lose self-control in SCD https://t.co/PNnXaROKYJ #redcellsironanderythropoiesis https://t.co/TKw1wtbkgL
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Mashup Score: 30Iron accelerates MDS progression - 26 day(s) ago
In this issue of Blood, Antypiuk et al, utilizing a murine model, demonstrate that iron overload (IOL), accumulated via a mutation in the iron importer fer
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
Iron accelerates MDS progression https://t.co/7JoPlbOkMA #redcellsironanderythropoiesis https://t.co/7VdJANS6Ly
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Mashup Score: 11Revisiting γ-globin gene repression by TR4 - 1 month(s) ago
In this issue of Blood, Wang et al revisit the important topic of γ-globin gene repression in adult erythropoiesis, and the role played by TR4, an orphan s
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
Revisiting γ-globin gene repression by TR4 https://t.co/gEgIgnM0VT #redcellsironanderythropoiesis https://t.co/rJurFsQSIV
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Mashup Score: 38Prevention of stroke in sickle cell disease - 2 month(s) ago
In this issue of Blood, Oluwole et al address the important question of the incidence of stroke in adults as well as in children with sickle cell disease (
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
Prevention of stroke in sickle cell disease https://t.co/dMFPx74qQk #redcellsironanderythropoiesis https://t.co/ZtlfsX1KjB
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Mashup Score: 37Prevention of stroke in sickle cell disease - 2 month(s) ago
In this issue of Blood, Oluwole et al address the important question of the incidence of stroke in adults as well as in children with sickle cell disease (
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
Prevention of stroke in sickle cell disease https://t.co/dMFPx74qQk #redcellsironanderythropoiesis https://t.co/ZtlfsX1KjB
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Mashup Score: 10Evaluation of hemoglobin S percent threshold to prevent severe pain events: a secondary analysis of the SIT trial - 2 month(s) ago
TO THE EDITOR:
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet-
Evaluation of hemoglobin S percent threshold to prevent severe pain events: a secondary analysis of the SIT trial https://t.co/9KdxGi4PfY #redcellsironanderythropoiesis
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Increased cardiac output, sarcomere length, mitochondrial content, and morphology highlight adaptive benefits in G6PD-deficient mice. https://t.co/dPuGjnX0sE #redcellsironanderythropoiesis https://t.co/T6Y9jbv60B