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Mashup Score: 2Atrial arrhythmia in adults with sickle cell anemia: a missing link toward understanding and preventing strokes - 6 hour(s) ago
Key PointsAA is common in middle-aged patients with SCA and is associated with an increased risk for stroke.Age and LA volume are associated with an increa
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 5Impact of iron overload on incidence of diabetes mellitus, cardiac disease, and death in congenital hemolytic anemias - 8 hour(s) ago
Key PointsIron overload in adults with congenital hemolytic anemias is associated with incidence of diabetes mellitus, cardiac disease, and death.Peak ferr
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 20Consensus recommendations for severe aplastic anemia - 2 day(s) ago
TO THE EDITOR:
Source: ashpublications.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 6
Key PointsGLUT1 knockout does not impair erythroid differentiation and minimally affects reticulocyte membrane composition.Metabolic adaptation facilitates
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 17Targeting PKCα alleviates iron overload in diabetes and hemochromatosis through the inhibition of ferroportin - 2 month(s) ago
Key PointsPKCα is novel and positive regulator of Fpn by modulating the trafficking and localization of Fpn.Inhibition of PKCα reduces body iron content in
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Mashup Score: 6Targeting PKCα decreases iron overload in diabetes - 2 month(s) ago
In this issue of Blood, Banerjee et al elucidate a novel mechanism underlying iron overload in diabetes.1 They demonstrate that protein kinase C alpha (PKC
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Mashup Score: 10Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine - 2 month(s) ago
Key PointsWe describe the phenotypes of mouse models of XLSA, the SLC25A38 anemia, and XLPP.XLSA and SLC25A38-CSA are conditionally synthetically lethal wi
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Mashup Score: 4Pyridoxine: beyond a cofactor of ALAS - 2 month(s) ago
In this issue of Blood, Ducamp and colleagues1 provide important insights into the pathophysiology of erythroid heme synthesis disorders by establishing vi
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Mashup Score: 28Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis - 2 month(s) ago
Key PointsFoxo1 regulates hepcidin expression and systemic iron homeostasis.Foxo1 could serve as a therapeutic target for hereditary hemochromatosis.
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 28Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis - 2 month(s) ago
Key PointsFoxo1 regulates hepcidin expression and systemic iron homeostasis.Foxo1 could serve as a therapeutic target for hereditary hemochromatosis.
Source: ashpublications.orgCategories: General Medicine News, Oncologists1Tweet
Age and LA volume are associated with an increased risk for AA and may be parameters for future risk stratification. https://t.co/vQt6h4XAxq #redcellsironanderythropoiesis https://t.co/UN5jjLii9c