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Mashup Score: 0Considerations for Choosing T Cell Assays during a Pandemic - 10 month(s) ago
Abstract. The appropriate immunosurveillance tools are foundational for the creation of therapeutics, vaccines, and containment strategies when faced with outbr
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Mashup Score: 1Antisense Oligonucleotide Therapy Decreases IL-1β Expression and Prolongs Survival in Mutant Nlrp3 Mice - 10 month(s) ago
Key Points. Nlrp3-specific ASO treatment downregulates Nlrp3 expression and IL-1β release in murine CAPS.Nlrp3-specific ASO treatment reduces systemic inflammat
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Mashup Score: 0Th1 Cells Alter the Inflammatory Signature of IL-6 by Channeling STAT Transcription Factors to Alu-like Retroelements - 10 month(s) ago
Key Points. Th1 cells alter the transcriptional output of IL-6 during acute inflammation.IL-6 and IFN-γ activities combine to steer tissue responses to inflamma
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Mashup Score: 4SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor - 10 month(s) ago
Key Points. SARS-CoV-2 ORF8 but not IL-17 upregulates cytokines in monocytes/macrophages.Monocytes and macrophages infected with SARS-CoV-2 do not express IL-17
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Mashup Score: 0The Journal of Immunology - 10 month(s) ago
Read the current issue of The Journal of Immunology.
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Mashup Score: 0The Journal of Immunology - 10 month(s) ago
Read the current issue of The Journal of Immunology.
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Mashup Score: 4“Doubt No More”: Two Sizes Fit All - 10 month(s) ago
This Pillars of Immunology article is a commentary on “Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones,” a pivotal articl
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Mashup Score: 4Nonbinary Roles for T Follicular Helper Cells and T Follicular Regulatory Cells in the Germinal Center Response - 10 month(s) ago
Abstract. Development of high-affinity Abs in the germinal center (GC) is dependent on a specialized subset of T cells called “T follicular helper” (TFH) cells
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Mashup Score: 0Recent Thymic Emigrants Require RBPJ-Dependent Notch Signaling to Transition into Functionally Mature Naive T Cells - 11 month(s) ago
Key Points. Recent thymic emigrants transition into mature naive cells via a CD45RBint stage.Immature naive T cells require Notch signals to undergo functional
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Mashup Score: 0Proteogenomic and V(D)J Analysis of Human Decidual T Cells Highlights Unique Transcriptional Programming and Clonal Distribution - 11 month(s) ago
Key Points. scRNA/CITE-seq results show that decidual T cells maintain a unique transcriptome.Decidual T cells overexpress negative regulators of inflammatory p
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#BriefReview by Jaclyn Law & former #JI_editor @Tania_WattsUofT @UofT discussing “Considerations for choosing #TCellAssays during a #pandemic” #ReadTheJI #immunology #SARSCoV2 #TCells #COVID 👉 https://t.co/oqV6IxfztE https://t.co/Y3MuYer0xo