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Mashup Score: 0Tumour antigen spreading mediated by vaccine-boosted CAR T cells - 1 year(s) ago
A preprint by Ma et al. investigates the mechanism of antigen spreading induced by a vaccine-boosted CAR T cell approach, which has implications for the therapeutic challenges associated with tumour heterogeneity or tumour antigen loss.
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 2Dynamics of antigen retention by follicular dendritic cells - 2 year(s) ago
A preprint by Martinez-Riano et al. evaluates the dynamics of antigen retention by follicular dendritic cells (FDCs) in germinal centres, showing that immune complexes accumulate in the centre of the FDC network.
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
NEW Journal Club by @nicolas_ruffin @estergeama @preprintclub discusses a #preprint by Martinez-Riano et al. @biorxivpreprint that evaluates the dynamics of antigen retention by follicular dendritic cells in germinal centres https://t.co/V4OMoawS08
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Mashup Score: 5Does de-identification of data from wearable Biometric Monitoring Technologies give us a false sense of security? A systematic review - 2 year(s) ago
It remains unknown whether de-identifying wearable biometric monitoring data is sufficient to protect the privacy of individuals in the dataset. This systematic review seeks to shed light on this. We searched Web of Science, IEEE Xplore Digital Library, PubMed, Scopus, and the ACM Digital Library on December 6, 2021 (PROSPERO CRD42022312922). We also performed manual searches in journals of…
Source: medRxivCategories: Cardiologists, Latest HeadlinesTweet-
'...substantial re-identification risk exists in data from sensors generally not thought to generate identifiable information' - blockbuster #preprint from @drjessilyn Lucy Chikwetu and team. @DukeMedSchool @medrxivpreprint #privacy @cziscience https://t.co/KthdOOwagi https://t.co/7uhup0htKG
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Mashup Score: 0The role of information infrastructures in scaling up video consultations during Covid-19: a time of opportunity, disruption and exposure - 2 year(s) ago
Journal of Medical Internet Research – International Scientific Journal for Medical Research, Information and Communication on the Internet
Source: JMIR PreprintsCategories: Healthcare Professionals, Latest HeadlinesTweet-
Check out our #JMIR #Preprint: The role of information infrastructures in scaling up video consultations during Covid-19: a time of opportunity, disruption and exposure https://t.co/WxvPd4r2aA #digitalhealth via @jmirpub Anyone want to peer review?
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Mashup Score: 1Causal effects on complex traits are similar across segments of different continental ancestries within admixed individuals - 2 year(s) ago
Individuals of admixed ancestries (e.g., African Americans) inherit a mosaic of ancestry segments (local ancestry) originating from multiple continental ancestral populations. Their genomic diversity offers the unique opportunity of investigating genetic effects on disease across multiple ancestries within the same population. Quantifying the similarity in causal effects across local ancestries…
Source: medRxivCategories: Cardiologists, Latest HeadlinesTweet-
REALLY interesting #preprint with lots to unpack! Important point about inflation in estimates of heterogeneity of causal effects when using marginal effects, due to differences in LD across local ancestries. https://t.co/v4ap8Xvvcz https://t.co/U1kB7DlvJg
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Mashup Score: 0Tissue-specific epigenomics of resident memory CD8+ T cells - 2 year(s) ago
A preprint by Buquicchio et al. looks at the chromatin landscape of memory CD8+ T cells over the course of their development during acute and chronic viral infections.
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
NEW Journal Club by Thi My Hanh Luong & @marcus_buggert @preprintclub discusses a #preprint by Buquicchio et al. @biorxivpreprint that looks at the chromatin landscape of CD8 T cells during acute and chronic viral infections https://t.co/jaefoi1WNp
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Mashup Score: 0XXtra killer cells - 2 year(s) ago
A preprint by Cheng et al. describes how differential expression of the X-chromosome-encoded epigenetic regulator UTX contributes to sex-based differences in natural killer cell frequency and function.
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
NEw Journal Club by @Ashleykr16 and @AdamFarkasPhD @preprintclub discusses a #preprint by Cheng et al. @biorxivpreprint describing differential expression of X-chromosome-encoded UTX in sex-based NK cell differences https://t.co/H4HL8yqDyb
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Mashup Score: 1
Deep learning has been shown to accurately assess ‘hidden’ phenotypes and predict biomarkers from medical imaging beyond traditional clinician interpretation of medical imaging. Given the black box nature of artificial intelligence (AI) models, caution should be exercised in applying models to healthcare as prediction tasks might be short-cut by differences in demographics across disease and…
Source: arXiv.orgCategories: Cardiologists, Latest HeadlinesTweet-
🔑 https://t.co/D8ClQthkRY https://t.co/svZbzlE9ZR
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🚨Important new #preprint led by @grantmduffy & @David_Ouyang! Proud to contribute!🚨 It's been shown that #AI can predict #race from medical images. We think it's critical to understand WHY. Spoiler alert: confounders confounders everywhere https://t.co/D8ClQthkRY
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Mashup Score: 15
Background Whether there are sex differences in hemodynamic profiles among people with elevated blood pressure is not well understood and could guide personalization of treatment. Methods and results We described the clinical and hemodynamic characteristics of adults with elevated blood pressure in China using impedance cardiography. We included 45,082 individuals with elevated blood pressure…
Source: medRxivCategories: Cardiologists, Latest HeadlinesTweet-
Great thing about @medrxivpreprint ... you preprint & then when your paper is published, you're notified by email, and there's a link on the #preprint page to the published article. Here we posted in Feb. Published in July. All linked. https://t.co/sez0ZexrJd @PLOSONE @jsross119 https://t.co/Ozk62K4lUb
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Mashup Score: 0The CD58–CD2 axis in cancer immune evasion - 2 year(s) ago
A preprint by Ho et al. investigates the role of decreased CD58 expression in cancer cell immune evasion, through both lack of T cell co-stimulation and increased T cell inhibition.
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet-
NEW Journal Club by Max Quastel & @MichaelLDustin @preprintclub discusses a #preprint by Ho et al. @biorxivpreprint that investigates decreased CD58 expression in cancer immune evasion - through lack of T cell costimulation and increased T cell inhibition https://t.co/7QrCYSHWXM
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NEW Journal club by Jaime Mateus-Tique & Brian Brown @preprintclub discusses a #preprint by Ma et al. @biorxivpreprint that investigates the mechanisms of antigen spreading induced by a vaccine-boosted CAR T cell approach https://t.co/qll6uXBrTE