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Mashup Score: 3
Investigators have identified previously unknown sets of epigenetic changes in pediatric brain tumors, which could serve as novel therapeutic targets and provide alternative treatment options.
Source: News CenterCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1
Skip Nav Destination ACCEPTED MANUSCRIPT RESOURCE ARTICLE| 14 May 2021 Lourdes Farre , 1Group of Chemoresistance and Predictive Factors, Subprogram…
Source: journals.biologists.comCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 12Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine - 4 year(s) ago
Patient-derived cancer models are essential tools for studying tumor biology and preclinical interventions. Here, we show that glioma patient-derived orthotopic xenografts (PDOXs) enable long-term propagation of patient tumors and represent clinically relevant patient avatars. We created a large collection of PDOXs from primary and recurrent gliomas with and without mutations in IDH1, which…
Source: bioRxivCategories: Hem/Oncs, Latest HeadlinesTweet
Previously unknown sets of #epigenetic changes in pediatric #braintumors could serve as therapeutic targets & guide precision medicine-based strategies, according to a study from @LurieCancer’s Xiao-Nan Li, MD, PhD in @NatureComms. https://t.co/Xvsz0fMoiH @NUFeinbergMed #PDOX https://t.co/GFP22ikE0k