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Mashup Score: 0
The recently released UK Chief Medical Officers Alcohol Guidelines Review set up new restricted limitations in alcohol consumption—14 units, the same amount for both men and women. In parallel, the popular Dry January campaign was launched again, aimed at promoting prolonged abstinence. Are these campaigns enough to give up boozing?
Source: www.nature.comCategories: General Medicine News, GastroenterologyTweet
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Mashup Score: 0
Understanding why individuals with Down syndrome are highly predisposed to autoimmunity has broad mechanistic and therapeutic implications. New work identifies novel potential mechanistic pathways driving increased autoimmunity-relevant CD11c+ B cells and provides the broadest view to date of the repertoire of autoantibodies generated in individuals with Down syndrome.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#JulyIssue | This #NewsAndViews discusses the risk of autoimmunity in Down syndrome and how insights into the underlying mechanisms might pave the way towards new and/or personalized treatment of autoimmune disease Check it out here: https://t.co/pGk4oHQxL1
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Mashup Score: 0Osteoarthritis research is failing to reach consumers - Nature Reviews Rheumatology - 12 month(s) ago
Given that intra-articular injections for the knee of treatments such as hyaluronic acid, stem cells and platelet-rich plasma are advised against or only weakly recommended by current clinical-practice guidelines, why do people continue to seek information about these treatments?
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
Online now! In this #NewsandViews, @vickyduong and @ProfDavidHunter discuss why online interest in intra-articular injections for knee #osteoarthritis doesn't match up with the latest evidence on effectiveness. https://t.co/S1AUjgXEAd https://t.co/vpvYo13jZG
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Mashup Score: 0Real-world data provide insights into PsA treatment patterns - Nature Reviews Rheumatology - 12 month(s) ago
Among the wide range of drugs now available for the treatment of psoriatic arthritis, the best option for an individual patient remains unclear. Emerging real-world evidence from several Nordic registries suggests that differences exist in the response rates to different classes of biologic and targeted synthetic DMARDs in psoriatic arthritis.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
In this #NewsandViews, Marzo-Ortega and Harrison discuss insights from real-world data on treatment of #PsoriaticArthritis https://t.co/9ZIYkTaGPO https://t.co/Xngva2q60G
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Mashup Score: 0How does citrullination contribute to RA autoantibody development? - Nature Reviews Rheumatology - 12 month(s) ago
The onset of the destructive autoimmune joint disease rheumatoid arthritis (RA) is preceded by the development of autoantibodies to multiple citrullinated proteins. Research has now shown that citrullination modifies antigen processing, resulting in the production of cryptic epitopes, suggesting a new model for RA autoantibody development.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
Check out this #NewsandViews on the contribution of #citrullination to #autoantibody development in #RheumatoidArthritis https://t.co/Uaxazjk5b3 https://t.co/3cKOo2gqqQ
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Mashup Score: 0
Among the limited quality and quantity of evidence on vaccination use in individuals with rheumatic and musculoskeletal diseases, a new guideline, developed with a rigorous methodology, provides useful support to clinicians and patients in making health-related decisions. Most recommendations are conditional, serving as a call to action for further research.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#MayIssue | This #NewsandViews discusses a new #ACR #vaccination guideline for patients with #rheumatic and #musculoskeletal diseases, which supports health-related decision-making. https://t.co/Sj2K8zSUJZ https://t.co/7cH2uXo136
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Mashup Score: 0The potential contribution of in silico studies to improved treatment of osteoarthritis - Nature Reviews Rheumatology - 1 year(s) ago
Osteoarthritis has many appearances and can stabilize or progress aggressively. However, there is not yet an aetiological classification of osteoarthritis subtypes. Can in silico approaches, despite difficulties in validation, help with the identification of experimentally challenging subtypes? And if they can, will these approaches translate to clinical benefits?
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#MayIssue | This #NewsandViews discusses whether in silico approaches can help with the identification of experimentally challenging subtypes of #osteoarthritis, and whether such approaches can translate to clinical benefits. https://t.co/qv17An6drG https://t.co/6xCVo2jqMr
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Mashup Score: 0The new look of classification criteria for systemic vasculitis - Nature Reviews Rheumatology - 1 year(s) ago
An ambitious project to update the classification of vasculitis syndromes has culminated in the development of new classification criteria for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, Takayasu arteritis and giant cell arteritis. Endorsed by the ACR and EULAR, the new criteria reflect progress in the understanding and assessment of these conditions.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#AprilIssue | The new look of #classification criteria for systemic #vasculitis Giacomo Emmi and Augusto Vaglio discuss the new ACR/EULAR classification criteria in the #NewsAndViews article https://t.co/oYs8CuGD3M
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Mashup Score: 7
Lack of understanding of the immunology of sarcoidosis has limited therapeutic progress. However, evidence from a small open-label trial suggests that treatment with the Janus kinase inhibitor tofacitinib can improve sarcoidosis symptoms, predominantly by inhibiting type 1 immunity.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#OctoberIssue | A lack of understanding of the immunology of #sarcoidosis has limited therapeutic progress. Can the #JAKinib #tofacitinib ‘slay the dragon’? Read more in this #NewsandViews article https://t.co/KCDZMEQaiE
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Mashup Score: 2Kawasaki disease and MIS-C share a host immune response - Nature Reviews Rheumatology - 2 year(s) ago
Multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease are both hyperinflammatory disorders associated with infectious diseases, but are they distinct syndromes or do they exist along a continuum? A comparison of the host immune response in these illnesses provides surprising new insights.
Source: NatureCategories: Latest Headlines, RheumatologyTweet-
#OctoberIssue | MIS-C and Kawasaki disease are both hyperinflammatory disorders associated with infectious diseases, but are they distinct syndromes or do they exist along a continuum? Read more in this #NewsandViews article https://t.co/DRGMiUmP2t
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Read-only link to the #NewsandViews from 2016 if you'd like to read more https://t.co/zDVMPCWZlq https://t.co/CgizaNlp9H