• Mashup Score: 1

    Genomic alterations in metastatic castration-resistant prostate cancer can be identified in plasma circulating tumour DNA. A large cohort analysis shows reliable detection of clinically relevant alterations through targeted cell-free DNA sequencing with a commercial platform, paving the way for liquid biopsy technology to be integrated into routine clinical practice.

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    • #NEWinNRU in this News&Views Sarah W. S. Ng & @ResearchWyatt discuss circulating tumour DNA assays for metastatic castration-resistant #ProstateCancer https://t.co/TVFKgkUC8R https://t.co/MxE6nPVHS5

  • Mashup Score: 0

    Survival of patients with metastatic prostate cancer has improved with the approval of second-generation androgen receptor antagonists. This Review discusses common genomic alterations leading to inevitable resistance to this therapy, and potential alternative therapeutic targets for treatment.

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    • #NEWinNRU @Keith_T_Schmidt Alwin D. R. Huitema, Cindy H. Chau & @WilliamFigg1 discuss resistance to second-generation androgen receptor antagonists in #ProstateCancer in a new Review https://t.co/fqYCw6H09E https://t.co/IrHDq4zfuf

  • Mashup Score: 0

    The new Bladder Cancer Research Centre at the University of Birmingham unifies the university’s multidisciplinary bladder cancer research activity within a single research centre, working within five core research themes to translate biomedical science into health-care benefits for patients with bladder cancer.

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    • #NEWinNRU in this Comment, Bryan et al. describe the setting up of the Bladder Cancer Research Centre at @unibirmingham https://t.co/105Z7i500v https://t.co/89mG2PY70l

  • Mashup Score: 11

    Access options Subscribe to JournalGet full journal access for 1 year$209.00only $17.42 per issueSubscribeAll prices are NET prices. VAT will be added later in the…

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    • #NEWinNRU in this Research Highlight we describe recently published work in @NatureComms by @ZiadBakouny @DrChoueiri @VanAllenLab @LabSignoretti et al. characterizing sarcomatoid and rhabdoid RCC #KidneyCancer https://t.co/xtzGqC4ozy

  • Mashup Score: 2

    Mobile health (mHealth) technologies hold great potential to advance medical care. However, widespread adoption in urology, and medicine in general, has been limited by a host of factors. Recognition of these barriers to adoption may instruct more meaningful tool development and investigation in order to unlock the full potential of these digital health tools in our field.

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    • #NEWinNRU @jwinokerMD @kvnkoo & @BrianMatlaga comment on the barriers to the adoption and integration of patient-facing mHealth tools in #urology https://t.co/zxj7y9Ck40 https://t.co/hZjURlWLKf

  • Mashup Score: 2

    New technical modifications enable transperineal prostate biopsy to be performed in the ambulatory setting under local anaesthesia. Although a variety of techniques for administration of local anaesthetic during transperineal prostate biopsy have been described, no consensus exists regarding the most effective method to use. Thus, ample opportunity exists for procedural innovation and future…

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    • #NEWinNRU in this Comment the authors discuss local anaesthetic techniques for performing transperineal prostate biopsy @michael_gorin @EdwardSchaeffer @ashleyrossmdphd @jimhumd @allaway_matthew https://t.co/wosdLEojMP https://t.co/gZDFnh2Yjz

  • Mashup Score: 2

    Asia is traditionally considered to have a low incidence of prostate cancer, but the incidence and mortality of prostate cancer have rapidly increased across the continent. Taking into account this intracontinental and intercontinental heterogeneity, translational studies are required in order to develop ethnicity-specific treatment strategies.

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    • #NEWinNRU @yao_zhu_sh @SFreedlandMD et al. on epidemiology and genomics of #ProstateCancer in Asian men https://t.co/fs4vkX0zlQ https://t.co/nOxOGbNANi

  • Mashup Score: 2

    Prostate cancer lends itself to gene therapies, and multiple aspects of prostate cancer care make gene therapy an appealing treatment option for this common malignancy. Although laboratory and preclinical advances have not yet resulted in oncologically relevant outcomes in the clinic, future studies offer great promise for gene therapy to become established in prostate cancer treatment.

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    • #NEWinNRU @JustinRGregg & Thompson consider the potential for gene-based therapy in #ProstateCancer https://t.co/fYqcOiRfrU https://t.co/IPAR5ZGwIO

  • Mashup Score: 2

    An effective transurethral resection of bladder tumour (TURBT) is essential to achieve safe tumour clearance and to determine the biological potential of the cancer. Attention to surgical detail within a set-up that embraces evidence-based practice, training, quality standards, prospective audit and feedback will facilitate these objectives.

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    • #NEWinNRU A News&Views from @ParamMariappan on how attention to detail and a permissive set-up are crucial for an effective TURBT for #BladderCancer https://t.co/biTQU68OsK https://t.co/CD8dChV6OR