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Mashup Score: 1Building confidence in circulating tumour DNA assays for metastatic castration-resistant prostate cancer - 3 year(s) ago
Genomic alterations in metastatic castration-resistant prostate cancer can be identified in plasma circulating tumour DNA. A large cohort analysis shows reliable detection of clinically relevant alterations through targeted cell-free DNA sequencing with a commercial platform, paving the way for liquid biopsy technology to be integrated into routine clinical practice.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 0
Survival of patients with metastatic prostate cancer has improved with the approval of second-generation androgen receptor antagonists. This Review discusses common genomic alterations leading to inevitable resistance to this therapy, and potential alternative therapeutic targets for treatment.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 0
The new Bladder Cancer Research Centre at the University of Birmingham unifies the university’s multidisciplinary bladder cancer research activity within a single research centre, working within five core research themes to translate biomedical science into health-care benefits for patients with bladder cancer.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 11Characterizing sarcomatoid and rhabdoid RCC - 3 year(s) ago
Access options Subscribe to JournalGet full journal access for 1 year$209.00only $17.42 per issueSubscribeAll prices are NET prices. VAT will be added later in the…
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 2
Mobile health (mHealth) technologies hold great potential to advance medical care. However, widespread adoption in urology, and medicine in general, has been limited by a host of factors. Recognition of these barriers to adoption may instruct more meaningful tool development and investigation in order to unlock the full potential of these digital health tools in our field.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 2
New technical modifications enable transperineal prostate biopsy to be performed in the ambulatory setting under local anaesthesia. Although a variety of techniques for administration of local anaesthetic during transperineal prostate biopsy have been described, no consensus exists regarding the most effective method to use. Thus, ample opportunity exists for procedural innovation and future…
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 2Epidemiology and genomics of prostate cancer in Asian men - 3 year(s) ago
Asia is traditionally considered to have a low incidence of prostate cancer, but the incidence and mortality of prostate cancer have rapidly increased across the continent. Taking into account this intracontinental and intercontinental heterogeneity, translational studies are required in order to develop ethnicity-specific treatment strategies.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 3Late adverse effects and quality of life in survivors of testicular germ cell tumour - 3 year(s) ago
Currently, ~95% of patients with testicular germ cell tumour are cured. Although cured, these men face potential late adverse effects and reduced quality of life. This Review outlines these adverse effects with recommendations on how to minimize their severity.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 2
Prostate cancer lends itself to gene therapies, and multiple aspects of prostate cancer care make gene therapy an appealing treatment option for this common malignancy. Although laboratory and preclinical advances have not yet resulted in oncologically relevant outcomes in the clinic, future studies offer great promise for gene therapy to become established in prostate cancer treatment.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
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Mashup Score: 2
An effective transurethral resection of bladder tumour (TURBT) is essential to achieve safe tumour clearance and to determine the biological potential of the cancer. Attention to surgical detail within a set-up that embraces evidence-based practice, training, quality standards, prospective audit and feedback will facilitate these objectives.
Source: Nature Reviews UrologyCategories: Latest Headlines, UrologyTweet
#NEWinNRU in this News&Views Sarah W. S. Ng & @ResearchWyatt discuss circulating tumour DNA assays for metastatic castration-resistant #ProstateCancer https://t.co/TVFKgkUC8R https://t.co/MxE6nPVHS5