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    Long term outcomes of lung transplantation are impacted by the occurrence of chronic lung allograft dysfunction (CLAD). Recent evidence suggests a role for the lung microbiome in the occurrence of CLAD, but the exact mechanisms are not well defined. We hypothesize that the lung microbiome inhibits epithelial autophagic clearance of pro-fibrotic proteins in an IL-33 dependent manner, thereby…

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    • #Originalscience showing #CLAD is associated with ⏫airway IL-33 expression & reduced basal autophagy. Pseudomonas in #lungtransplant induces fibrogenic response by inhibiting airway epithelial autophagy in an IL-33 dependent manner. @NirmalSSharmaMD 🔗:https://t.co/Eyn9ZDf4rI https://t.co/r8fnpx0qgb

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    CHARLOTTE, N.C. — Among patients who underwent lung transplantation, laparoscopic Toupet fundoplication provided objective acid reflux control and preserved lung function and foregut motility, according to late-breaking data. “Gastroesophageal reflux disease with microaspiration is a modifiable risk factor for lung transplant rejection,” Sheetal Patel, MD, a third-year fellow in

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    • #ICYMI from #ACG2022: Toupet fundoplication could become preferred #antireflux procedure after #lungtransplant #GITwitter #MedTwitter https://t.co/irnACG6qfW

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    The number of lung transplant procedures performed internationally is increasing but the donor organ pool is insufficient to meet demand and waiting list mortality is unacceptably high. As survival rates for patients with acute respiratory distress syndrome managed on extracorporeal life support (ECLS) have steadily improved, a potential role for ECLS to support critically ill patients awaiting a…

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    • Extracorporeal life support as a bridge to #lungtransplant – who, when, how, why? The answers to these questions and more are included in this review written by experts from across the globe. #ECMO @DrCMPatterson @MarceloCypel @KHoetzenecker @pacman8it 🔗:https://t.co/uNZjLZHrNC https://t.co/K3aWaLHe43

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    Harvesting a well-preserved and undamaged pair of donor lungs is vital for a good outcome after a lung transplant. This video shows the authors’ retrieval technique, which has been standardized and is easy to follow and fully reproducible by fellows with minimal assistance. The goals of a donor lung retrieval include: 1. Careful assessment of lungs, including bronchoscopy, inspection, palpation,…

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    • “Donor Lung Harvest—The Indian Technique” | Dr. Ali demonstrates his technique for donor lung harvest in a #lungtransplant procedure, emphasizing the importance of careful assessment of the lungs, meticulous dissection, and careful preservation. https://t.co/OnFRDjf0is https://t.co/vwMhYq7rJF