• Mashup Score: 49
    Wolters Kluwer Health - 2 year(s) ago

    JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…

    Source: lww.com
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      🚨New Paper🚨 😅 My first first author Big ⬇️ in #LDL #Cholesterol while #keto ... from... Big ⬆️ in saturated fat?!? 🤔🤔🤔 👉Tightly controlled prospective case experiment in duplicate 👉N=24 case series replicate 👉Why the #LEM might explain it... https://t.co/BLRudkMHBD

  • Mashup Score: 1
    LMHR roundtable with Harvard Doctors - 2 year(s) ago

    In this video, I interview three HARVARD DOCTORS from the Massachusetts General Hospital (MGH) about Lean Mass Hyper-Responders (LMHR) and the Lipid Energy M…

    Source: YouTube
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      👨‍⚕️👨‍⚕️👨‍⚕️ I was incredibly honored to host a roundtable with some amazing @Harvard doctors @albertsymd & Dr Victor Neel discussing their insights on #LDL #Cholesterol, #CardiovascularDisease🫀, and our recent research on the #LEM⚡️ and #LMHRs. 🙏@nicknorwitz https://t.co/eHErzhi0D0

  • Mashup Score: 1
    The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets - 2 year(s) ago

    When lean people adopt carbohydrate-restricted diets (CRDs), they may develop a lipid profile consisting of elevated LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) with low triglycerides (TGs). The magnitude of this lipid profile correlates with BMI such that those with lower BMI exhibit larger increases in both LDL-C and HDL-C. The inverse association between BMI and LDL-C and HDL-C change…

    Source: MDPI
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      4/ Conversely, myself (and #LEM coauthors) posit it is more predominantly the Lipid Energy Model that explains higher #LDL in this context.* This is why the RER readings were integral to the experiment when we first started talking about... (*See https://t.co/6stRMjjybz)

  • Mashup Score: 1
    Thoughts Regarding LDL-P, ApoB, and Remnants - 2 year(s) ago

    This week, Peter Attia released Measuring cardiovascular disease risk and the importance of apoB on his blog. I think it’s well worth the read and highly encourage you to finish it first befo…

    Source: Cholesterol Code
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      6/ Of course, I've touched on this area many times before (#LEM), but this article I wrote a while ago from CC goes into this very specific area in depth: https://t.co/u0zOWwSg0Y

  • Mashup Score: 1
    The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets - 2 year(s) ago

    When lean people adopt carbohydrate-restricted diets (CRDs), they may develop a lipid profile consisting of elevated LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) with low triglycerides (TGs). The magnitude of this lipid profile correlates with BMI such that those with lower BMI exhibit larger increases in both LDL-C and HDL-C. The inverse association between BMI and LDL-C and HDL-C change…

    Source: MDPI
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      1/2 🚨🚨🚨BREAKING🚨🚨🚨 👉👉👉Long awaited #LipidEnergyModel/#LEM Hypothesis Paper is now published!!! 🙏Please Retweet🙏 👉Why #LDL #Cholesterol might ⬆️ on #keto 👉How #LEM could explain #LMHR phenotype 👉Implications for lipid metabolism overall https://t.co/6stRMjjybz

  • Mashup Score: 1
    Comment on: Mark’s “Making of a LMHR” - 2 year(s) ago

    Recently, Mark Lightell, a 29-year-old endurance athlete, took it upon himself to try to convert to the LMHR phenotype with a two-week n=1 experiment. You can find Mark’s post about this experience…

    Source: Cholesterol Code
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      2/3 Given Mark is lean and fit, he he seemed like an excellent candidate to help test #LEM directly. But as an added bonus, @nicknorwitz is also commenting on it for us with his companion piece here: https://t.co/dr5TVsr8fO

  • Mashup Score: 3
    Accelerated turnover of very low density lipoprotein triglycerides in chronic alcohol users - 2 year(s) ago

    The concentration of high density lipoproteins (HDL) is related to the catabolism of triglyceride-rich lipoproteins. In order to elucidate the mechanisms by which alcohol increases plasma HDL levels we measured the turnover kinetics of very low density lipoprotein (VLDL) triglycerides in 10 alcoholic men without liver disease and in nonalcoholic control men matched for age, weight and plasma VLDL…

    Source: Atherosclerosis
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      It's a crucial question. Certainly one factor @nicknorwitz and I are especially interested in is VLDL turnover to ↗️HDL (hello, #LEM). Per my earlier comment, there are experiments that induces these changes in this context of alcoholism, like this one: https://t.co/t5lWkhYt2i https://t.co/d82iFePWIX https://t.co/S1zgtmtSy1

  • Mashup Score: 1
    Stanford University Lecture for the Lipid Energy Model - 2 year(s) ago

    I was incredibly honored to be invited by Annelise E. Barron, Associate Professor, Dept. of Bioengineering, to present my research to her class and discuss t…

    Source: YouTube
    Categories: Hem/Oncs, Latest Headlines
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      realDaveFeldman

      Yes, would love to chat #LDL #Cholesterol with @hubermanlab. Ironically, I gave a talk to @Stanford two years ago on the #LipidEnergyModel/#LEM regarding to lipids & metabolism 👇 -- which is now getting developed as a paper with the amazing @nicknorwitz https://t.co/yLbUzz6pkU https://t.co/lJAW4jEocA