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    Five of the world’s leading societies combine their research to create FREE Article Collection By continuing to browse this site, you agree to its use of cookies as described in our Privacy Policy

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    • #EB2020 may have been cancelled, but you can still read this special virtual collection of articles from 5 leading societies: https://t.co/PqZEgNSuAr @BrJPharmacol @BritJClinPharm @PRandP_Journal #hypoxia #inflammation #ionchannels #microbiome https://t.co/K9yM8x6nbW

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    Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal ‘firing’ in the central nervous system and for brain and heart function. These channels use a “ball-and-chain” mechanism to help regulate their ion flow, according to a new study led by Weill Cornell Medicine scientists.

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    • Ball-and-chain inactivation of #ionchannels visualized by cryo-electron microscopy @WeillCornell @nature https://t.co/j5W0MXgebr

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    Mechanotransduction has a key role in vascular development, physiology, and disease states. Piezo1 is a mechanosensitive (MS) nonselective cationic channel that occurs in endothelial and vascular smooth muscle cells. It is activated by shear stress associated with increases in local blood flow, as well as by cell membrane stretch upon elevation of blood pressure. Here, we briefly review the…

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    • Read about piezo #ionchannels in cardiovascular #mechanobiology in @Trendsin Pharma https://t.co/K95a6HQYnK #bps20