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Mashup Score: 2Wolters Kluwer Health - 2 year(s) ago
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Source: lww.comCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
Therapeutic hypothermia did not reduce the combined outcome of death or disability at 18 months after neonatal encephalopathy in low-income and middle-income countries, but significantly increased death alone. Therapeutic hypothermia should not be offered as treatment for neonatal encephalopathy in low-income and middle-income countries, even when tertiary neonatal intensive care facilities are…
Source: The Lancet Global HealthCategories: Latest Headlines, PediatricsTweet-
#HELIX is such a key study in my mind along the likes of #FEAST. It shows that a therapy that works in #HIC may necessarily work in #LMIC. #Hypothermia for neonatal #HIE in 🇮🇳🇧🇩🇱🇰 I suspect there are nuances for why this didn't work #neotwitter @LancetGH https://t.co/mBIbnZ8IEU
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Mashup Score: 1Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature - Critical Care - 3 year(s) ago
Background Fever and hypothermia have been observed in septic patients. Their influence on prognosis is subject to ongoing debates. Methods We did a secondary analysis of a large clinical dataset from a quality improvement trial. A binary logistic regression model was calculated to assess the association of the thermal response with outcome and a multinomial regression model to assess factors…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA #Fever & #hypothermia are both responses to human #sepsis https://t.co/K50yDKf4uG #FOAMed #FOAMcc #BMC @ISICEM @jlvincen #ICU #lactate #body_temperature #mortality #blood_culture https://t.co/440UqOa1I1
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Mashup Score: 5Wolters Kluwer Health - 3 year(s) ago
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Source: lww.comCategories: Emergency Medicine, Latest HeadlinesTweet-
.@AliRaja_MD & @Rick_Pescatore review the latest on whether to use therapeutic #hypothermia after #cardiacarrest. They also talk about patient awareness during sedation and how much information is retained from listening to podcasts like this one! #FOAMed https://t.co/QmPq93iTtW
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Mashup Score: 22Targeted temperature management and cardiac arrest after the TTM-2 study - Critical Care - 3 year(s) ago
Critical Care volume 25, Article number: 275 (2021) Cite this article …
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA Targeted #temperature management & #cadiac_arrest: pros & cons https://t.co/OR5cYAs0nH #FOAMed #FOAMcc #BMC @ISICEM @jlvincen #cardiac_arrest #intensive_care #TTM_2 #hypothermia #neurology https://t.co/2EPaKRc2Du
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Mashup Score: 2Wolters Kluwer Health - 3 year(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Emergency Medicine, Latest HeadlinesTweet-
.@AliRaja_MD & @Rick_Pescatore review the latest on whether to use therapeutic #hypothermia after #cardiacarrest. They also talk about patient awareness during sedation and how much information is retained from listening to podcasts like this one! #FOAMed https://t.co/QmPq93iTtW
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Mashup Score: 3
Therapeutic hypothermia did not reduce the combined outcome of death or disability at 18 months after neonatal encephalopathy in low-income and middle-income countries, but significantly increased death alone. Therapeutic hypothermia should not be offered as treatment for neonatal encephalopathy in low-income and middle-income countries, even when tertiary neonatal intensive care facilities are…
Source: The Lancet Global HealthCategories: Latest Headlines, PediatricsTweet-
#Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (#HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh https://t.co/eMrhtFcHu7 #HIE #TH #PedsICU #FoamNeo #NeoEBM
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Mashup Score: 4
The p53 tumor suppressor is frequently inactivated by mutations in cancer. Most p53 mutations are located in the DNA-binding domain, causing local disruption of DNA-binding surface or global misfolding. Rescuing the structural defect of mutant p53 is an attractive therapeutic strategy, but its potential remains unproven due to a lack of drugs capable of efficiently rescuing misfolded p53….
Source: Cancer ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Study by Lu et al shows that durable remission was achieved in a temperature-sensitive lymphoma model by induction of 32˚C whole-body #hypothermia that rescued p53 transcriptional activity and induced #TumorRegression. https://t.co/ZLBBp1N0xY https://t.co/RQxllvMoP1
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Mashup Score: 3NEJM Journal Watch: Summaries of and commentary on original medical and scientific articles from key medical journals - 3 year(s) ago
NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary
Source: www.jwatch.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
No Benefit to #Hypothermia Compared w/ #Normothermia After #CardiacArrest @Jdankiewicz MD, et al. @NEJM @JWatch https://t.co/24bNeOlBlG [subscription] https://t.co/QVDZTtAUvh
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Mashup Score: 8Effect of intra-arrest trans-nasal evaporative cooling in out-of-hospital cardiac arrest: a pooled individual participant data analysis - 3 year(s) ago
Background Randomized trials have shown that trans-nasal evaporative cooling initiated during CPR (i.e. intra-arrest) effectively lower core body temperature in out-of-hospital cardiac arrest patients. However, these trials may have been underpowered to detect significant differences in neurologic outcome, especially in patients with initial shockable rhythm. Methods We conducted a post hoc…
Source: Critical CareCategories: Critical Care, Latest HeadlinesTweet-
#CritCare #OA intra-arrest #cooling & #neurological outcome in out-of-hospital #cardiac_arrest https://t.co/fhWIDQIzYQ #FOAMed #FOAMcc #BMC #Hypothermia #heart @ISICEM @jlvincen https://t.co/LG3Gsd67Pi
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Wisløff-Aase et al: LV Changes Induced by Mod #Hypothermia Rapidly Reversed After Rewarming 20 pts ❤️Bypass Link: https://t.co/ieYeT8YkMN #CritCareMed @SCCM #ultrasound #POCUS Fig: LV parameters diff temp https://t.co/hwSVDh6Xs9