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Mashup Score: 2Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma - PubMed - 1 year(s) ago
We identified specific gene isoforms in both the canonical and non-canonical HIF pathways associated with metastatic RCC survival. EGLN3 and BNIP3 showed significant interaction with treatment arm and may be predictive of treatment response. We have identified genes for future prospective investigat …
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Breakthrough science: hypoxia-inducible factors, oxygen sensing, and disorders of hematopoiesis - 1 year(s) ago
Edited by Associate Editor Mario Cazzola, this review series highlights 3 specific areas of scientific and clinical advances in understanding disorders of red c
Source: American Society of HematologyCategories: Hem/Oncs, Latest HeadlinesTweet-
Breakthrough science: hypoxia-inducible factors, oxygen sensing, and disorders of hematopoiesis👇 https://t.co/3oQYPrgUwM @JohnsHopkins | #HIF #O2 https://t.co/WUt3bhDDxH
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Mashup Score: 1Hypoxia-inducible factors: roles in cardiovascular disease progression, prevention, and treatment - 2 year(s) ago
Abstract. Hypoxia-inducible factors HIF-1 and HIF-2 are master regulators of oxygen homeostasis that regulate the expression of thousands of genes in order to m
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet-
To inhibit or not to inhibit?⚖️ State-of-the-art #CardiovascularResearch Review weighs inhibition & activation of #hypoxia inducible factor (#HIF) as therapeutic strategies for #CVD❤️🩹 https://t.co/7F3G11xXwK @CVR_TomaszGuzik @DrMikeDrozd @glenpyle #ischemia #ESCBasicScience https://t.co/sWbR2YoAiA
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Mashup Score: 3
Targeting ineffective hematopoiesis in Myelodysplastic Syndromes
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet-
Targeting ineffective hematopoiesis in Myelodysplastic Syndromes. https://t.co/3qQziAIzKj #HIF #Roxadustat #PHD2 #VHL Editorial on #MATTERHORN trial of Roxadustat in #MDS with Dr. Valeria Santini @MayoCancerCare
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Mashup Score: 0Enzyme discovery is missing piece in understanding how to rein in blood vessels that fuel cancer - 3 year(s) ago
By unleashing the power of an enzyme that limits blood vessel growth, it may be possible to develop new or better treatments for multiple health conditions. December 22, 2020 LA JOLLA, CA—Most living things need oxygen to grow and thrive. Even cancerous tumors. That’s why tumors will readily sprout new blood vessels if their oxygen is starved, creating new lifelines for…
Source: www.scripps.eduCategories: General Medicine News, Latest HeadlinesTweet-
#cancer needs oxygen to survive, which is why tumors readily sprout new blood vessels. Prof Xiang-Lei Yang’s lab has now discovered a way to prevent this process by inhibiting #HIF and #VEGF signaling https://t.co/lxXnEmaI1t @PLOSBiology https://t.co/FyBPTXH6Dt
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Mashup Score: 4Homepage - ENA 2020 - 4 year(s) ago
ENA 2020 is the drug development and translational research meeting, focusing on preclinical & phase I studies and the latest developments in targets and drugs.
Source: ENA 2020Categories: Hem/Oncs, Latest HeadlinesTweet-
I cannot wait for #ENASYMP20 sponsored by @EORTC @theNCI @AACR . Exceptional program by Drs. Gulley @gulleyj1 @nciccr_gmb, Sellers @broadinstitute and Calvo @TheSTARTCenter. I am humbled to give a Keynote with Sir Peter Ratcliffe @TheCrick https://t.co/nst4RKRUj4 #HIF #VEGF #RCC https://t.co/EdalRDc6pf
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Mashup Score: 1Resolving the HIF paradox in pancreatic cancer - 4 year(s) ago
Pancreatic ductal adenocarcinoma (PDAC) is currently the third leading cause of cancer-related deaths and has a 5-year survival rate of less than 10%,…
Source: www.sciencedirect.comCategories: Hem/Oncs, Latest HeadlinesTweet-
RT @OncologyAdvance: Now in #CancerLetters Resolving the #HIF paradox in #PancreaticCancer https://t.co/Ns8iVaHpuK by @TaniguchiMD and coll…
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Mashup Score: 1Resolving the HIF paradox in pancreatic cancer - 4 year(s) ago
Pancreatic ductal adenocarcinoma (PDAC) is currently the third leading cause of cancer-related deaths and has a 5-year survival rate of less than 10%,…
Source: www.sciencedirect.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Now in #CancerLetters Resolving the #HIF paradox in #PancreaticCancer https://t.co/Ns8iVaHpuK by @TaniguchiMD and colleagues @MDAndersonNews https://t.co/oPPKA6b2Tf
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Much deserved and huge congrats to new uro chair @CedarsSinai @HyungLKim still has time to run our biweekly #GU onc multi-D TB and highly collaborative - check out our recent @UrolOncol work on #HIF gene isoforms as novel biomarkers and targets in #ccRCC https://t.co/bBtkODH6n4 https://t.co/NkvemsesWJ https://t.co/Cv65ygbXkE