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Mashup Score: 0Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
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Mashup Score: 4Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 3Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 5Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 7Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 4Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials - 1 year(s) ago
This genome-wide pharmacogenomic study of GLP-1 receptor agonists provides novel biological and clinical insights. Clinically, when genotype is routinely available at the point of prescribing, individuals with ARRB1 variants might benefit from earlier initiation of GLP-1 receptor agonists.
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Mashup Score: 1Predicting the response to GLP-1 receptor agonists: an unexpected role for β-arrestin-1 - 1 year(s) ago
Drugs targeting glucagon-like peptide 1 (GLP-1) and its heterotrimeric G protein-coupled receptor (GPCR) are important therapies for type 2 diabetes.1 GLP-1 is an incretin hormone which potentiates glucose-stimulated insulin secretion after meals. After binding to its receptor on β cells (GLP1R), GLP-1 activates a cascade of intracellular regulators, including the Gαs subunit, which activates…
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Mashup Score: 2Glucose-lowering drugs with cardiovascular benefits as modifiers of critical elements of the human life history - 1 year(s) ago
The life history theory assumes that all organisms are under selective pressure to harvest external resources and allocate them to maximise fitness: only organisms making the best use of energy obtain the greatest fitness benefits. The trade-off of energy spans four functions: maintenance, growth, reproduction, and defence against pathogens. The innovative antihyperglycaemic agents glucagon-like…
Categories: Endocrinology, Latest HeadlinesTweet
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