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Mashup Score: 0
A phase 2 clinical trial (NCT04558346) of ghrelin (OXE103; Oxeia Biopharmaceuticals, San Diego, CA) for treating concussions has been initiated. The c
Source: Practical NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 7
The hormone ghrelin has been discovered to be a key regulator of new nerve cells in the adult brain, and may lead to new treatments for Parkinson’s disease.
Categories: Future of Medicine, Latest HeadlinesTweet-
Gut Hormone Found to Play Critical Role in Parkinson’s Disease Dementia. Learn more: https://t.co/Q5xdvhLa4P #dementia #ghrelin #parkinsons https://t.co/c17sR67rPh
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Mashup Score: 1The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a - 4 year(s) ago
Ghrelin is a peptide that is secreted by the stomach during fasting to promote food intake. The accessory protein MRAP2 interacts with the ghrelin receptor GHSR1a and is important for the orexigenic effects of ghrelin. Rouault et al. found that MRAP2 promoted biased signaling downstream of ghrelin-mediated activation of GHSR1a by inhibiting β-arrestin recruitment to the receptor and potentiating…
Source: Science SignalingCategories: Future of MedicineTweet-
The latest research in @SciSignal highlights a mechanism that can bias and fine-tune the activity of the receptor for #ghrelin, a hormone that stimulates appetite and hunger. #BiasedSignaling https://t.co/U6245MFARc https://t.co/v3gYIkxgP6
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Mashup Score: 7The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a - 4 year(s) ago
Ghrelin is a peptide that is secreted by the stomach during fasting to promote food intake. The accessory protein MRAP2 interacts with the ghrelin receptor GHSR1a and is important for the orexigenic effects of ghrelin. Rouault et al. found that MRAP2 promoted biased signaling downstream of ghrelin-mediated activation of GHSR1a by inhibiting β-arrestin recruitment to the receptor and potentiating…
Source: Science SignalingCategories: Future of MedicineTweet-
The latest research in @SciSignal highlights a mechanism that can bias and fine-tune the activity of the receptor for #ghrelin, a hormone that stimulates appetite and hunger. #BiasedSignaling https://t.co/U6245MFARc https://t.co/aoSRjgkL5B
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#Ghrelin Advances to a Phase 2 Trial for #Concussion Treatment #neurology #PracticalNeurology https://t.co/6q0oSd9SU9