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Mashup Score: 0Top Reads - 1 year(s) ago
Chlamydia pneumoniae Infection Promotes Metabolic Dysfunction See article p. 1086DC2s Coordinate Early Tumor Immunity See article p. 1146Bead-Based Assay to Ass
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Mashup Score: 0Multistep IgE Mast Cell Desensitization Is a Dose- and Time-Dependent Process Partially Regulated by SHIP-1 - 1 year(s) ago
Key Points. Mast cell multistep IgE-desensitization is a time- and dose-dependent process.Desensitization uncouples signal transduction and FcεRI/IgE/Ag interna
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#AuthorChoice from Mariana Castells @BrighamWomens: Silencing SHIP-1 impaired #IgE desensitization | #FreetoRead #ReadTheJI #immunology #mastcells 👉 https://t.co/evDekd1fDK https://t.co/mjCw3yESEx
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Mashup Score: 1Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity - 1 year(s) ago
Key Points. We demonstrate a causal link between prolidase deficiency and autoimmunity.Loss of PEPD leads to an Ag-independent increase in effector CD8 T cells.
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#AuthorChoice: Prolidase deficiency causes spontaneous #Tcell activation and #lupus-like #autoimmunity | from @BetterKidneys @UniofOxford #FreetoRead #ReadTheJI #immunology 👉 https://t.co/DVHAAXawyY https://t.co/ET5mSdIIKM
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Mashup Score: 0Group 2 Innate Lymphoid Cells Are Detrimental to the Control of Infection with Francisella tularensis - 1 year(s) ago
Key Points. Enhancing ILC2 numbers increases Francisella tularensis bacterial burden.Reducing ILC2 numbers promotes Francisella tularensis bacterial clearance.I
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#AuthorChoice: negative role for #ILC2s in the control airway F. tularensis infection from @TravislabUoM @OfficialUoM #FreetoRead #tularemia #ReadTheJI #immunology 👉 https://t.co/Wbmio8MdX4 https://t.co/xC6MUCKLQt
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Mashup Score: 0Top Reads - 1 year(s) ago
Abstract. Age-Associated Deficits in CD8 Virtual Memory T Cells See article p. 297LPS Protects from Paramyxovirus Infection See article p. 348
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The #JI_TopRead summaries are #FreetoRead and are meant to help keep you up to date on some of the hottest #immunology research. #ReadTheJI February 1, 2023 summaries here 👉 https://t.co/nXMIVUzBB3 https://t.co/BrRlfb5V8D
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Mashup Score: 0AL008 Enhances Myeloid Antitumor Function by Inhibiting SIRPα Signaling and Activating Fc Receptors - 1 year(s) ago
Key Points. AL008 induces SIRPα degradation and immune activation through FcγR2A engagement.AL008 promotes T cell proliferation more effectively than anti-CD47
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#JI_TopRead from Andrew Pincetic @AlectorTx | #SIRPα Ab as a potential anti-tumor therapeutic that stimulates both the innate and adaptive immune responses #immunotherapies #tumorimmunology#ReadTheJI #immunology #FreetoRead 👉 https://t.co/A1zbG37poV https://t.co/CfLtjB6WpK
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Mashup Score: 0Top Reads - 1 year(s) ago
Abstract. Adjuvant for Polysaccharide Vaccines See article p. 148AL008 Promotes Antitumor Immunity See article p. 204
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Save some time this week and read the summaries of the #JI_TopRead articles for Jan. 15, 2023 #FreetoRead #sciencehighlights #ReadtheJI 👉 https://t.co/RbNTvSSOUV https://t.co/5kg1B6nkm3
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Mashup Score: 3Regulation of Synovial γδ T Cell Ligand Expression by Mitochondrial Reactive Oxygen Species and Gasdermin-D - 1 year(s) ago
Key Points. Human synovial TCR-γδ ligand is induced on monocytes by TLR stimuli.Ligand surface expression is dependent on gasdermin-D and is redox sensitive.Lig
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#AuthorChoice: synovial #γδTcell ligand is a self-antigen whose surface expression is increased by inflammatory conditions & #mitochondrialstress from Ralph C. Budd @UVMLarnerMed #FreetoRead #TCR #reactiveoxygenspecies #ReadTheJI #immunology 👉 https://t.co/ODFb24qx7E https://t.co/txmcsZ9dxF
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Mashup Score: 6Mass Spectrometry Defines Lysophospholipids as Ligands for Chicken MHCY Class I Molecules - 1 year(s) ago
Key Points. Mass spectrometry analyses show that chicken MHCY class I molecules bind lysophospholipids.MHCY class I molecules differing significantly in sequenc
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#AuthorChoice: lysophospholipids are candidate ligands for #MHC class I using mass spectrometry | from Marcia M. Miller @cityofhope #FreetoRead #chickenimmunology #ReadTheJI #immunology 👉https://t.co/76M5ySm2js https://t.co/DWhleLUJFo
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Mashup Score: 0
Key Points. cTECs undergo progressive changes during postnatal life caused by loss of Foxn1.Foxn1− cTECs remain within the cortex but lack cTEC signature genes.
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#JI_TopRead from @UobAnderson @ImmunologyUoB | cTECs are heterogeneous & play different roles in #thymocyte development depending on gene expression programs | #FreetoRead #epithelialcells #stromalcells #ReadTheJI #immunology @news_ub @unibirm_MDS 👉 https://t.co/OOeSnoauuP https://t.co/EAC9Lhq6Of
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The Top Reads summaries from the April 15, 2023 issue are #FreetoRead. In each issue, we summarize selected articles, curated by the editors, to help keep you up to speed on the latest immunology discoveries wherever you read! 👉 https://t.co/V7eez1CGVh https://t.co/cpzbGb6VSg