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Mashup Score: 0
An 80-year-old woman was assessed for cutaneous edema at the site of her intravenous (IV) access during infusion of normal saline (Figure 1). She had no associated symptoms and was otherwise well. The same reaction occurred in the contralateral arm with dextrose 5%. She was treated with IV diphenhydramine and the reaction subsided.
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Mashup Score: 0Pediatric-onset aspirin-exacerbated respiratory disease: Clinical characteristics, prevalence, and response to dupilumab - 2 year(s) ago
Aspirin-exacerbated respiratory disease (AERD) is characterized by asthma, chronic rhinosinusitis with nasal polyposis (CRSwNP), and respiratory reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygenase-1. The syndrome occurs in about 7% of adults with asthma and 25-30% of adults with asthma and CRSwNP.1 AERD is primarily a disease of adult-onset and has a female…
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Mashup Score: 2Hypereosinophilia Following Aspirin Desensitization for Aspirin Exacerbated Respiratory Disease - 2 year(s) ago
Mitchell M. Pitlick, MD Mitchell M. PitlickCorrespondenceCorresponding author: Mitchell Pitlick, MD, Mayo Clinic, Division of Allergic, Diseases, 200 First Street SW, Rochester, MN, 55905 Phone: 507-538-7746. [email protected]AffiliationsDivision of Allergic Diseases, Mayo Clinic, Rochester, MN, USA This paper is only…
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Mashup Score: 1Utility of Nasal Mucus Inflammatory Profile as a Biomarker of Nasal Polyp Regrowth in Aspirin-Exacerbated Respiratory Disease - 2 year(s) ago
Article InfoPublication HistoryAccepted: March 18, 2022Received in revised form: March 17, 2022Received: January 25, 2022Publication stageIn Press Journal Pre-ProofFootnotesEmail Addresses: Kristen Corey – [email protected] Justin Turner – [email protected] Naweed Chowdhury – [email protected] Rakesh Chandra – …
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Mashup Score: 2
Nonsteroidal anti-inflammatory drug (NSAID)–exacerbated respiratory disease (N-ERD) comprises the triad of chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, and intolerance to inhibitors of the cyclooxygenase-1 enzyme. The impact of omalizumab on prevention of aspirin-induced hypersensitivity in N-ERD patients with and without atopic sensitization has not been thoroughly addressed.
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Mashup Score: 1Appraisal of the Real-World Effectiveness of Biologic Therapies in Aspirin-Exacerbated Respiratory Disease - 2 year(s) ago
There are no head-to-head studies for patients with aspirin-exacerbated respiratory disease (AERD) comparing any of the 5 Food and Drug Administration–approved respiratory biologic therapies.
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Mashup Score: 1Aspirin desensitization or biologics for aspirin-exacerbated respiratory disease – How to choose? - 2 year(s) ago
Aspirin-exacerbated respiratory disease (AERD) can be a frustratingly complex syndrome to treat. Until recently, standard medical and surgical therapies for patients’ asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP) were the primary treatment modalities available, combined with either complete avoidance of all aspirin and non-steroidal anti-inflammatory medications, or with aspirin…
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Mashup Score: 2Appraisal of the Real-World Effectiveness of Biologic Therapies in Aspirin-Exacerbated Respiratory Disease - 3 year(s) ago
There are no head-to-head studies for patients with aspirin-exacerbated respiratory disease (AERD) comparing any of the five FDA approved respiratory biologic therapies.
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Mashup Score: 3
Aspirin-exacerbated respiratory disease (AERD), the triad of asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and respiratory reactions to cyclooxygenase-1 inhibitors, is characterized by difficult-to-treat upper and lower respiratory symptoms. It is a type 2–mediated inflammatory disease marked by blood and tissue eosinophilia, dysregulated cysteinyl leukotriene production, and mast…
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Mashup Score: 1
Early in the severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic, asthma was understood to be a risk factor for poor outcomes in those infected. Yet, as understanding of the disease matured, asthma was not consistently observed as a risk factor. Because asthma is a heterogeneous disorder, asthma endotypes may impact coronavirus 2019 (COVID-19)-related morbidity.
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In Press! #Cold- #Induced #Urticaria #Exacerbated During Treatment With #Pembrolizumab https://t.co/a26y8uOOYG