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Mashup Score: 0Study Shows Heart Failure Treatment With Dapagliflozin Consistently Benefited Both Men and Women - 2 year(s) ago
November 14, 2022 — When it comes to heart failure (HF), sex differencesare known to impact everything from risk factors to clinical presentation to response to treatment, making sex a key factor to consider in studies of emerging pharmacotherapies. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, such as dapagliflozin, have become an important pharmacotherapy solution for patients with HF, yet…
Source: DAICCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2Dapagliflozin and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction - 2 year(s) ago
This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney function.
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet-
#DELIVER 🔥 #Dapa efficacy in #HFmrEF & #HFpEF across the full spectrum of renal function 🧩 Another piece of the puzzlereinforcing the recent metanalysis on #SGLT2i on kidney function @mvaduganathan @BrighamResearch @gcfmd @KardiologieHH @DrMarthaGulati https://t.co/UvhNzEFbP1 https://t.co/hOoiIWQRWt
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Mashup Score: 1
In patients with heart failure with mildly reduced or preserved ejection fraction, oral dapagliflozin improved heart failure outcomes to a similar extent in three glycaemia subgroups: normoglycaemia, prediabetes, and type 2 diabetes. Moreover, the heart failure benefits of dapagliflozin seem to be consistent across a continuous glycaemic range.
Categories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 5
In patients with heart failure with mildly reduced or preserved ejection fraction, oral dapagliflozin improved heart failure outcomes to a similar extent in three glycaemia subgroups: normoglycaemia, prediabetes, and type 2 diabetes. Moreover, the heart failure benefits of dapagliflozin seem to be consistent across a continuous glycaemic range.
Categories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 3Home | delivertrial - 2 year(s) ago
DELIVER was a randomized, placebo-controlled, double-blind international clinical outcomes trial testing the hypothesis that dapagliflozin compared with placebo would reduce the risk of cardiovascular death or worsening heart failure in patients with heart failure with mildly reduced or preserved ejection fraction.
Source: delivertrialCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Home | delivertrial - 2 year(s) ago
DELIVER was a randomized, placebo-controlled, double-blind international clinical outcomes trial testing the hypothesis that dapagliflozin compared with placebo would reduce the risk of cardiovascular death or worsening heart failure in patients with heart failure with mildly reduced or preserved ejection fraction.
Source: delivertrialCategories: Cardiologists, Latest HeadlinesTweet-
New #DELIVER trial website just launched summarizing publications to date. A glimpse at 3 #AHA22 simpub & 2 related articles containing #DELIVER data to be pub at this meeting. Impressively, website entirely homegrown by sole designer: @scottdsolomon https://t.co/4rSHsGb6pQ https://t.co/NpXoeWEfwR https://t.co/anNXFj7FLg
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Mashup Score: 9Dapagliflozin and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction - 2 year(s) ago
This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney function.
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet-
#Dapagliflozin and Kidney Outcomes in Patients With #HeartFailure With Mildly Reduced or Preserved Ejection Fraction : A Prespecified Analysis of the #DELIVER Trial #HeartFailure #HFpEF #HFmrEF https://t.co/YP24gmTeMM @JavedButler1 @scottdsolomon @DrMarthaGulati @kidney_boy https://t.co/ZYcFXbbSNa https://t.co/ohhmVI51tx
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Mashup Score: 12Dapagliflozin and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction - 2 year(s) ago
This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney function.
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet-
#DELIVER Kidney now #SimPub w @ASNKidney/#KidneyWk LBCT in @JAMACardio ⭐️Consistent dapa safety & benefit on HF outcomes across eGFR range (down to 20) ⭐️Dapa predictable early eGFR dip & slowed long-term eGFR decline ⭐️Very few kidney composite outcomes https://t.co/LVLQYlP9vC https://t.co/4nL2Vwu8dN
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Mashup Score: 2In HF, dapagliflozin benefits similar in patients with improved vs. consistently high EF - 2 year(s) ago
NATIONAL HARBOR, Md. — In a DELIVER subgroup analysis, dapagliflozin conferred similar benefit in patients with HF with improved ejection fraction prior to trial enrollment compared with those with consistently high EF.“Heart failure with improved ejection fraction … has been recently defined as heart failure with previously reduced left ventricular ejection fraction of 40% or less,
Source: www.healio.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Time to Clinical Benefit of Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction - 2 year(s) ago
This prespecified secondary analysis of the DELIVER trial evaluates the time course of benefits of dapagliflozin on clinically relevant outcomes in patients with HF with mildly reduced or preserved ejection fraction.
Source: jamanetwork.comCategories: Cardiologists, Latest HeadlinesTweet-
#DELIVER 💡 Early & sustained #SGLT2i benefit in #HFmrEF & #HFpEF Significant after just 2 weeks 🔥 🌟 Another reason to "start today" in #HF @JavedButler1 @mvaduganathan @MarcoMetra @hvanspall @DrMarthaGulati @GMCRosano @mmamas1973 @iamritu https://t.co/iS9zrfLkcs @JAMACardio https://t.co/JCESX6h4c7 https://t.co/RdmVEWQNdN
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@DAICeditor @BWHCVImaging Investigators from Brigham and Women's Hospital conducted a study using a pre-specified patient-level pooled analysis of #DAPA_HF and #DELIVER: https://t.co/yJ6fyy5hVj #dapagliflozin #heartfailure