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    November 14, 2022 — When it comes to heart failure (HF), sex differencesare known to impact everything from risk factors to clinical presentation to response to treatment, making sex a key factor to consider in studies of emerging pharmacotherapies. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, such as dapagliflozin, have become an important pharmacotherapy solution for patients with HF, yet…

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    • @DAICeditor @BWHCVImaging Investigators from Brigham and Women's Hospital conducted a study using a pre-specified patient-level pooled analysis of #DAPA_HF and #DELIVER: https://t.co/yJ6fyy5hVj #dapagliflozin #heartfailure

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    This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney function.

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    • #DELIVER 🔥 #Dapa efficacy in #HFmrEF & #HFpEF across the full spectrum of renal function 🧩 Another piece of the puzzlereinforcing the recent metanalysis on #SGLT2i on kidney function @mvaduganathan @BrighamResearch @gcfmd @KardiologieHH @DrMarthaGulati https://t.co/UvhNzEFbP1 https://t.co/hOoiIWQRWt

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    Home | delivertrial - 2 year(s) ago

    DELIVER was a randomized, placebo-controlled, double-blind international clinical outcomes trial testing the hypothesis that dapagliflozin compared with placebo would reduce the risk of cardiovascular death or worsening heart failure in patients with heart failure with mildly reduced or preserved ejection fraction.

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    • RT @scottdsolomon: Ankeet Bhatt presented the #DELIVER Covid-19 data today at AHA. View presentation at https://t.co/Z5qR42jsDu https://t.c…

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    Home | delivertrial - 2 year(s) ago

    DELIVER was a randomized, placebo-controlled, double-blind international clinical outcomes trial testing the hypothesis that dapagliflozin compared with placebo would reduce the risk of cardiovascular death or worsening heart failure in patients with heart failure with mildly reduced or preserved ejection fraction.

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    • New #DELIVER trial website just launched summarizing publications to date. A glimpse at 3 #AHA22 simpub & 2 related articles containing #DELIVER data to be pub at this meeting. Impressively, website entirely homegrown by sole designer: @scottdsolomon https://t.co/4rSHsGb6pQ https://t.co/NpXoeWEfwR https://t.co/anNXFj7FLg

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    This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney function.

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    • #Dapagliflozin and Kidney Outcomes in Patients With #HeartFailure With Mildly Reduced or Preserved Ejection Fraction : A Prespecified Analysis of the #DELIVER Trial #HeartFailure #HFpEF #HFmrEF https://t.co/YP24gmTeMM @JavedButler1 @scottdsolomon @DrMarthaGulati @kidney_boy https://t.co/ZYcFXbbSNa https://t.co/ohhmVI51tx

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    This prespecified analysis of the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction Heart Failure (DELIVER) randomized clinical trial investigates if the effects of dapagliflozin on cardiovascular events vary with baseline kidney function.

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    • #DELIVER Kidney now #SimPub w @ASNKidney/#KidneyWk LBCT in @JAMACardio ⭐️Consistent dapa safety & benefit on HF outcomes across eGFR range (down to 20) ⭐️Dapa predictable early eGFR dip & slowed long-term eGFR decline ⭐️Very few kidney composite outcomes https://t.co/LVLQYlP9vC https://t.co/4nL2Vwu8dN

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    NATIONAL HARBOR, Md. — In a DELIVER subgroup analysis, dapagliflozin conferred similar benefit in patients with HF with improved ejection fraction prior to trial enrollment compared with those with consistently high EF.“Heart failure with improved ejection fraction … has been recently defined as heart failure with previously reduced left ventricular ejection fraction of 40% or less,

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    • In a #DELIVER subgroup analysis, #dapagliflozin conferred similar benefit in patients with HF with improved EF prior to trial enrollment compared with those with consistently high EF @orlyvardeny @UMNews @HFSA #HFSA2022 #Cardiotwitter https://t.co/KMOirNP85U