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Mashup Score: 1Wolters Kluwer Health - 2 year(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1CARD9-Mediated Signaling and Cardiovascular Diseases: - 2 year(s) ago
IntroductionInflammation and oxidative stress are critical to the pathogenesis of cardiovascular diseases (CVDs) including atherosclerosis and heart failure. Proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and interferon (IFN)-γ, play a critical role in the initiation and maintenance of inflammation. The adaptor protein caspase-recruitment domain 9…
Categories: Expert Picks, Latest HeadlinesTweet
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Mashup Score: 4lincRNA-Cox2 Functions to Regulate Inflammation in Alveolar Macrophages during Acute Lung Injury - 2 year(s) ago
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/208/1831
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Fighting viruses is as easy as breathing - 2 year(s) ago
Human Lung Chip reveals the effects of breathing motions on lung immune responses and leads to repurposing of potential therapeutics for respiratory diseases, including COVID-19
Source: Wyss InstituteCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 5
Different components of the immune response show large variability between individuals, but they also vary within the same individual because of host and environmental factors. In this study, we report an extensive analysis of the immune characteristics of 56 individuals over four timepoints in 1
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 8
Different components of the immune response show large variability between individuals, but they also vary within the same individual because of host and environmental factors. In this study, we report an extensive analysis of the immune characteristics of 56 individuals over four timepoints in 1
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 1Innate Immune Memory and the Host Response to Infection - 2 year(s) ago
Unlike the adaptive immune system, the innate immune system has classically been characterized as being devoid of memory functions. However, recent research shows that innate myeloid and lymphoid cells have the ability to retain memory of prior pathogen exposure and become primed to elicit a robust, broad-spectrum response to subsequent infection. This phenomenon has been termed innate immune…
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Targeting downstream type 2 cytokines or upstream epithelial alarmins for severe asthma - 2 year(s) ago
Biologics, including omalizumab, mepolizumab, benralizumab and dupilumab targeting downstream immunoglobulin E (IgE), cytokines IL-5 and IL-4/13 respectively have shown promising effects in terms of reduction in annualised asthma exacerbation rates (AER), oral corticosteroid (OCS) sparing effects, improvements in forced expiratory volume in 1 second (FEV1), and improved asthma control…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 7
This article is featured in Top Reads , p.[][1] [1]: /lookup/volpage/208/195
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 9
IFNs are comprised of three families of cytokines that confer protection against pathogen infection and uncontrolled cellular proliferation. The broad role IFNs play in innate and adaptive immune regulation has placed them under heavy scrutiny to position them as “friend” or “foe” across pathologies. Genetic lesions in genes involving IFN synthesis and signaling underscore the disparate outcomes…
Source: The Journal of ImmunologyCategories: Allergy-Immunology, Latest HeadlinesTweet
In a systematic review and meta-analysis of related studies exploring the link between #inflammation and #depression in cancer patients found that inflammatory #cytokines contribute directly to depression by affecting neurotransmitters and neurocircuits: https://t.co/jivRuWu77Z https://t.co/pipSA6zLtu