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Mashup Score: 8Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis - 3 year(s) ago
Desai et al. show that the tuft cell/IL-4Rα circuit in the intestine can have detrimental consequences in the context of helminth and viral coinfection. Flavivirus infection of enteric neurons, in the setting of a type 2 immune response due to helminths, IL-25, or IL-4 signaling, impairs intestinal integrity and compromises host CD8+ T cell responses and survival.
Source: CellCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 22Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis - 3 year(s) ago
Desai et al. show that the tuft cell/IL-4Rα circuit in the intestine can have detrimental consequences in the context of helminth and viral coinfection. Flavivirus infection of enteric neurons, in the setting of a type 2 immune response due to helminths, IL-25, or IL-4 signaling, impairs intestinal integrity and compromises host CD8+ T cell responses and survival.
Source: CellCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
In the latest issue! Enteric helminth #coinfection enhances #host susceptibility to neurotropic #flaviviruses. https://t.co/U1IqctpdXf @WashUID @WUSTLmed https://t.co/dDasCNh7oH