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Mashup Score: 0Cancer Support Community Releases Report on Cancer Cachexia - 2 year(s) ago
Report Highlights Unmet Medical Needs of Patients Facing Unintentional Weight Loss, Muscle Weakness, and Fatigue…
Source: GlobeNewswire News RoomCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Cancer Support Community Releases Report on Cancer Cachexia - 2 year(s) ago
Report Highlights Unmet Medical Needs of Patients Facing Unintentional Weight Loss, Muscle Weakness, and Fatigue…
Source: GlobeNewswire News RoomCategories: Latest Headlines, Oncologists1Tweet-
RT @wendyselig: Proud to have authored this important Voice of the Patient report on #cancer #cachexia https://t.co/tWuPHyoXvk
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Mashup Score: 2LUNGevity Foundation is proud to be part of the winning Cancer Grand Challenges global team addressing cancer cachexia | LUNGevity Foundation - 2 year(s) ago
The team, composed of investigators from across the UK and US, will receive $25M to take on the challenge of cancer cachexia, the debilitating wasting condition responsible for up to 30% of cancer-related deaths. WASHINGTON, DC (June 16, 2022) — LUNGevity is honored to be the US patient advocacy organization that is part of the new Cancer Grand Challenges team taking on the challenge of cancer…
Source: www.lungevity.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
@LUNGevity is pleased to be the #advocacy partner on the @CancerGrand CANCAN project to address ongoing unmet needs related to #cancer #cachexia, including ID of better biomarkers and stratification of patient subgroups to deliver tailored Tx interventions https://t.co/kJ1zcvmkbR
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Mashup Score: 2Treating Cancer Cachexia: Progress Looks Possible - 2 year(s) ago
Some people with cancer develop cachexia, a wasting syndrome causing dramatic weight loss. Researchers are studying why—and testing new treatments for it.
Source: National Cancer InstituteCategories: Hem/Oncs, Latest HeadlinesTweet-
An excellent primer on #cachexia and the current state of cachexia science. Kudos to Carmen Phillips and @theNCI team. Great read for faculty, trainees, patients and caregivers. @letswinpc @LUNGevity https://t.co/J727JNSYFH https://t.co/bBCjt71Yf0
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Mashup Score: 0
Abstract. Immune checkpoint inhibition is dramatically improving patient outcomes in diverse cancers, many of which responded poorly to traditional cytotoxic agents. Drivers of heterogeneous response to immune checkpoint therapy are poorly characterized. Cachectic cancer patients exhibit elevated pembrolizumab clearance and poor response, highlighting the immense therapeutic challenge posed by…
Categories: Hem/Oncs, Latest HeadlinesTweet-
@pashtoonkasi @intraccsurvivor @ASCO @pashtoonkasi is on to something here. Patients with #cachexia show increased #Immunotherapy clearance and poorer outcomes with checkpoint inhibitor therapy https://t.co/iPqBOziFu7
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Mashup Score: 0CSHL’s Tobias Janowitz helps lead cancer team that won $25 mln in research funding | TBR News Media - 2 year(s) ago
By Daniel Dunaief If a team Cold Spring Harbor Laboratory Assistant Professor Tobias Janowitz co-leads succeeds, researchers will know more about the end stage of numerous types of cancer that involves the loss of tissue and muscle mass. Tobias Janowitz Recently, lead scientists Janowitz; Eileen White, Rutgers Cancer Institute of New Jersey Deputy Director and Chief Scientific Officer; and Dr….
Source: tbrnewsmedia.comCategories: Hem/Oncs, Latest HeadlinesTweet-
I am so thrilled that @LUNGevity and I are part of this amazing opportunity to change the face of #cancer #cachexia! CSHL’s Tobias Janowitz helps lead cancer team that won $25 mln in research funding https://t.co/MgaETaBU3Z via @TBR News Media
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Mashup Score: 3Analyzing cachectic phenotypes in the muscle and fat body of Drosophila larvae: STAR Protocols - 2 year(s) ago
Summary Drosophila has become a popular model for examining the metabolic wasting syndrome, cachexia, characterized by degradation of muscles and fat. Here we present a protocol for quick and consistent scoring of muscle detachment, fat body lipid droplet size, and extracellular matrix (ECM) quantifications in Drosophila larvae. We detail the procedures for dissecting,…
Source: star-protocols.cell.comCategories: General Medicine News, Latest HeadlinesTweet-
Online in @STARProtocols: Dr. Louise Cheng @PeterMacCC using #Drosophila as a model to examine the metabolic wasting syndrome, #cachexia: https://t.co/NLVrL8r0Ay 👉Muscle detachment analysis 👉Quantification of fat body lipid droplet size and ECM disruption https://t.co/jBStvNRvu9
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Mashup Score: 9
Conditions characterized by muscle wasting such as cachexia and sarcopenia are devastating at the individual level, and they place a profound burden on public health. Evidence suggests that inflammation is likely a mechanistic contributor to the pathogenesis of these conditions. One specific molecule, lipopolysaccharide, has gained attention due to its role in initiating inflammation. Toll-like…
Categories: Latest Headlines, RheumatologyTweet-
#Exercise elicits anti-inflammatory adaptations ▶️Reduce TLR-4-mediated inflammation ▶️Prevent progression of #muscle wasting conditions like cancer #cachexia & #sarcopenia 👉🏽https://t.co/se8HXdlDLw via @AJPCellPhys #PhysicalActivity https://t.co/YnUscYVreX
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Mashup Score: 0The critical role of STAT3 in biogenesis of tumor-derived exosomes with potency of inducing cancer cachexia in vitro and in vivo - Oncogene - 2 year(s) ago
Tumor-derived exosomes are emerging mediators of cancer cachexia. Clarifying the regulation of exosome biogenesis and finding possible targets for cancer cachexia therapy are important and necessary. In the present study, systemic analysis of the roles of STAT3 in controlling exosome biogenesis of murine C26 colon tumor cells and its contribution to the development of cancer cachexia is…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
A very interesting insight into the role of STAT3 & tumour-derived #exosomes in cancer #cachexia development. 👉 https://t.co/hvJVWdbpZZ
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Mashup Score: 9SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19 - 2 year(s) ago
COVID-19 is a spectrum of clinical symptoms in humans caused by infection with SARS-CoV-2. The B.1.1.529 Omicron variant is rapidly emerging and has been designated a Variant of Concern (VOC). The variant is highly transmissible and partially or fully evades a spectrum of neutralising antibodies due to a high number of substitutions in the spike glycoprotein. A major question is the relative…
Source: bioRxivCategories: Hem/Oncs, Latest HeadlinesTweet-
Less #cachexia seen in #omicron infected mice compared to #delta #covid19 SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19 | bioRxiv https://t.co/HlWBd0McQz
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Thank you for your leadership on this important topic (#cachexia) and often unmet need in patients with #cancer @CancerSupportHQ Support Community Releases Report on Cancer Cachexia https://t.co/tUtzvApOiv