• Mashup Score: 0

    Pregnancy success requires constant dialogue between the mother and developing conceptus. Such crosstalk is facilitated through complex interactions between maternal and fetal cells at distinct tissue sites, collectively termed the “maternal–fetal interface.” The emergence of single-cell technologies has enabled a deeper understanding of the unique processes taking place at the maternal–fetal…

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    • #JI_MaternalFetal_Immuno #BriefReview by @nardhygomez @waynestate discussing #SingleCell #Immunology of the #MaternalFetalInterface #ReadTheJI #MaternalFetalImmunology #SingleCellSequencing #RNAsequencing #SystemsImmunology https://t.co/gTvdEA376R https://t.co/27naEwMuDp

  • Mashup Score: 1

    Photosensitivity is a sensitivity to UV radiation (UVR) commonly found in systemic lupus erythematosus (SLE) patients who have cutaneous disease. Upon even ambient UVR exposure, patients can develop inflammatory skin lesions that can reduce the quality of life. Additionally, UVR-exposed skin lesions can be associated with systemic disease flares marked by rising autoantibody titers and worsening…

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    • #ICYMI: #BriefReview from #JI_Editor @TheresaLuLab | Immune Cell–Stromal Circuitry in #Lupus #Photosensitivity | #ReadTheJI #immunology https://t.co/YcQhAPdCpF https://t.co/yuUbmqR2OZ

  • Mashup Score: 6

    Seasonal influenza and the current COVID-19 pandemic represent looming global health challenges. Efficacious and safe vaccines remain the frontline tools for mitigating both influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–induced diseases. This review will discuss the existing strategies for influenza vaccines and how these strategies have informed SARS-CoV-2…

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    • #ICYMI: #BriefReview from @ImmunologyAAI President (2020-2021) Jenny P.Y. Ting @UNC_SOM: Strategies for #influenza #vaccines and how these strategies have informed #SARSCoV2 vaccines | #ReadTheJI #immunology #viralimmunity https://t.co/QmMOXSqiZi https://t.co/flouAv1dWm

  • Mashup Score: 7

    Retinoic acid–inducible gene I–like receptors (RLRs) are cytosolic RNA sensors critical for initiation of antiviral immunity. Activation of RLRs following RNA recognition leads to production of antiviral genes and IFNs for induction of broad antiviral immunity. Although the RLRs are ubiquitously expressed, much of our understanding of these molecules comes from their study in epithelial cells and…

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    • #BriefReview by @EmilyHemann @adforu and colleagues @OhioStateMed | #RIGI–like receptor regulation of immune cell Function and #therapeutic implications | #ReadTheJI #immunology #RNAsensors 👉 https://t.co/JmzEMR9o0X https://t.co/8ixSXTyv76

  • Mashup Score: 6

    Obesity is considered the primary environmental factor associated with morbidity and severity of wide-ranging inflammatory disorders. The molecular mechanism linking high-fat or cholesterol diet to imbalances in immune responses, beyond the increased production of generic inflammatory factors, is just beginning to emerge. Diet cholesterol by-products are now known to regulate function and…

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    • #BriefReview by @FrascoliMichela Andrea Reboldi, and Joonsoo Kang @UMass discussing Dietary #cholesterol #metabolite regulation of tissue #immunecell development and function https://t.co/45lwp4I97e #ReadTheJI #immunology https://t.co/9ROaEN3lwW