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Mashup Score: 6Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis - 2 year(s) ago
Abstract. Non-small cell lung cancer (NSCLC) is one of the most commonly diagnosed and deadliest cancers worldwide, with roughly half of all patients initially presenting with both primary and metastatic disease. While the major events in the metastatic cascade have been identified, a mechanistic understanding of how NSCLC routinely and successfully colonizes the brain is largely unknown. Recent…
Categories: Hem/Oncs, Latest HeadlinesTweet-
RT @EANOassociation: Developmental pathways are epigenetically reprogrammed during #LungCancer #BrainMetastasis. https://t.co/XjdKU48EBV #…
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Mashup Score: 9Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis - 2 year(s) ago
Melanoma-secreted amyloid beta, which suppresses inflammatory activation of astrocytes and microglia, is required for the growth and survival of melanoma cells within the brain, and pharmacologic inhibition of amyloid beta production significantly reduced brain metastatic burden in mice.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the May issue: #Melanoma-secreted #AmyloidBeta Suppresses Neuroinflammation and Promotes #BrainMetastasis, by @KleffmanKevin, Eva Hernando et al. https://t.co/PpROLG380H @nyulangone https://t.co/PWh9FN39nJ
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Mashup Score: 0Targeting S100A9–ALDH1A1–Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer - 2 year(s) ago
The S100A9–ALDH1A1–retinoic acid signaling pathway mediates osimertinib resistance and brain relapse in models of EGFR-mutant lung cancer.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the April issue: Targeting S100A9-ALDH1A1-retinoic acid signaling to suppress brain relapse in #EGFR-mutant #LungCancer by @anupkbiswas, @SwarnaliAchary5 et al. https://t.co/PvGmmehCD9 @columbiacancer @ColumbiaMed #Osimertinib #BrainMetastasis https://t.co/C8pHxqrVEX
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Mashup Score: 7Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis - 2 year(s) ago
AbstractBrain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has the highest rate of brain metastasis among common cancer types, is an ideal model to study how cancer cells adapt to the brain parenchyma. Our…
Categories: Hem/Oncs, Latest HeadlinesTweet-
RT @EANOassociation: #Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes #BrainMetastasis. https://t.co/nveQqsU2Y7 #…
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RT @EANOassociation: #Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes #BrainMetastasis. https://t.co/nveQqsU2Y7 #…
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Mashup Score: 2Julie Wu, MD, PhD @julie_t_wu @Stanford #IASLC22 #Brain - 2 year(s) ago
Julie Wu, MD, Ph.D., Medical Oncology Fellow at Stanford University. In this video, she speaks about the IASLC 2022 Abstract – The Impact of Molecular Driv
Source: www.oncologytube.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Molecular Driver Mutations In Brain Metastasis Julie Wu, MD, PhD @julie_t_wu @Stanford #IASLC22 #BrainMetastasis https://t.co/WCtDCoMp59 https://t.co/oghOVJ0LXq
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Mashup Score: 1Podcast Julie Wu, MD, PhD @julie_t_wu @Stanford #IASLC2 - 2 year(s) ago
Julie Wu, MD, Ph.D., Medical Oncology Fellow at Stanford University. In this video, she speaks about the IASLC 2022 Abstract – The Impact of Molecular Driv
Source: www.oncologytube.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Podcast - Molecular Driver Mutations In Brain Metastasis Julie Wu, MD, PhD @julie_t_wu @Stanford #IASLC22 #BrainMetastasis Link to Audio: https://t.co/ewPA5vHJfC https://t.co/atON6YBEqt
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Mashup Score: 4Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis - 2 year(s) ago
Abstract. Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has the highest rate of brain metastasis among common cancer types, is an ideal model to study how cancer cells adapt to the brain parenchyma….
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
RT @EANOassociation: Melanoma-secreted #AmyloidBeta Suppresses Neuroinflammation and Promotes #BrainMetastasis https://t.co/40p9E8xCDy #me…
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Mashup Score: 2Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis - 2 year(s) ago
Abstract. Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has the highest rate of brain metastasis among common cancer types, is an ideal model to study how cancer cells adapt to the brain parenchyma….
Categories: Hem/Oncs, Latest HeadlinesTweet-
RT @EANOassociation: Melanoma-secreted #AmyloidBeta Suppresses Neuroinflammation and Promotes #BrainMetastasis https://t.co/40p9E8xCDy #me…
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Mashup Score: 24Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis - 2 year(s) ago
Abstract. Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has the highest rate of brain metastasis among common cancer types, is an ideal model to study how cancer cells adapt to the brain parenchyma….
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Melanoma-secreted #AmyloidBeta Suppresses Neuroinflammation and Promotes #BrainMetastasis by @KleffmanKevin, Hernando et al. https://t.co/vU8E6nuuDg @nyulangone https://t.co/zsLw6sbxm7
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Mashup Score: 2Targeting S100A9-ALDH1A1-retinoic acid signaling to suppress brain relapse in EGFR-mutant lung cancer - 2 year(s) ago
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib has significantly prolonged progression-free survival (PFS) in EGFR-mutant lung cancer patients, including those with brain metastases. However, despite striking initial responses, osimertinib-treated patients eventually develop lethal metastatic relapse, often to the brain. Although osimertinib-refractory…
Source: Cancer DiscoveryCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Targeting S100A9-ALDH1A1-retinoic acid signaling to suppress brain relapse in #EGFR-mutant #lungcancer by Anup Kumar Biswas @SwarnaliAchary5 and colleagues @columbiacancer, @ColumbiaMed. https://t.co/qKfwp3RXmf #osimertinib #brainmetastasis https://t.co/AZfy3u33kN
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RT @EANOassociation: Developmental pathways are epigenetically reprogrammed during #LungCancer #BrainMetastasis. https://t.co/XjdKU48EBV #…