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    The normal incretin effect—an enhanced prandial insulin response—is mediated mostly by meal-stimulated release of the intestinal hormones GLP-1 and glucose-dependent insulinotropic peptide (GIP).1 Analogues of GLP-1 that act as GLP-1 receptor agonists are established glucose-lowering agents that potentiate insulin release and suppress glucagon in a glucose-dependent manner. GLP-1 receptor…

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    • Online: Clifford J Bailey comments on: #Tirzepatide: a new low for bodyweight and blood glucose https://t.co/Mr5SldRSGp #glycaemia #bodyweight #T2D #obesity