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    • Mashup Score: 10
      Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation - 14 day(s) ago

      PURPOSEAllogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for advanced hematologic malignancies. HSCT using human leukocyte antigen (HLA)-mismatched donors is historically associated with inferior survival. Patients from …

      Source: ascopubs.org
      Categories: General Medicine News
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        Post-Transplant Cyclophosphamide-Based GVHD Prophylaxis After Mismatched Unrelated Donor PB SCT @JCO_ASCO https://t.co/dRzdlsnaaQ @DrMonzrAlMalki @amjimenezmd #bmtsm

    • Mashup Score: 85
      Autologous Transplant or CAR‐T as Consolidation Options in MYC Rearranged Large B‐Cell Lymphoma Patients in Remission After Salvage Treatments - 2 month(s) ago

      Although recent studies have demonstrated the efficacy of chimeric antigen receptor T-cell (CAR-T) therapy in relapsed large B-cell lymphoma (LBCL) with MYC rearrangement (R-MYC), the data comparing …

      Source: onlinelibrary.wiley.com
      Categories: General Medicine News
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      • Profile photo of 	MediHumdani
        MediHumdani

        One-size does not fit all: If you ever happen to see a LBCL with excellent chemosensitivity: Auto in those circumstance still reasonable. @FateehaFurqan extends our previous work now to MYC rearranged LBCL @cibmtr #bmtsm https://t.co/EoyIgu47rU https://t.co/tLdQnbXSS4

    • Mashup Score: 76
      Autologous Transplant or CAR‐T as Consolidation Options in MYC Rearranged Large B‐Cell Lymphoma Patients in Remission After Salvage Treatments - 3 month(s) ago

      Although recent studies have demonstrated the efficacy of chimeric antigen receptor T-cell (CAR-T) therapy in relapsed large B-cell lymphoma (LBCL) with MYC rearrangement (R-MYC), the data comparing …

      Source: onlinelibrary.wiley.com
      Categories: General Medicine News
      Tweet Tweets with this article
      • Profile photo of 	MediHumdani
        MediHumdani

        One-size does not fit all: If you ever happen to see a LBCL with excellent chemosensitivity: Auto in those circumstance still reasonable. @FateehaFurqan extends our previous work now to MYC rearranged LBCL @cibmtr #bmtsm https://t.co/EoyIgu47rU https://t.co/tLdQnbXSS4

    • Mashup Score: 6
      Taming JAK cytokine release in haplo-transplant - 3 month(s) ago

      In this issue of Blood, Abboud and colleagues1 report the results of a phase 2 trial of itacitinib given as add-on to standard graft-versus-host disease (G

      Source: ashpublications.org
      Categories: General Medicine News
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        Taming JAK cytokine release in haplo-transplant #bmtsm https://t.co/VDO5SZCtyk

    • Mashup Score: 10
      Clonal dynamics after allogeneic haematopoietic cell transplantation - 8 month(s) ago

      Nature – Uprooting stem cells from their native environment and transplanting them to other individuals exaggerates selective pressures, distorting and accelerating the loss of clonal diversity in…

      Source: www.nature.com
      Categories: General Medicine News, Hematologists1
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      • Profile photo of 	melmehdi
        melmehdi

        RT @Wang_Yu_Hung: Clonal dynamics after allogeneic haematopoietic cell transplantation https://t.co/Y0BZdWIXNO #BMTsm @Nature @TheEBMT @Moh…

    • Mashup Score: 1
      Revisiting Timing and Decision Modeling for Allogeneic Hematopoietic Stem-Cell Transplantation in Myelodysplastic Syndromes | Journal of Clinical Oncology - 10 month(s) ago

      The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors’ suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice.

      Source: ascopubs.org
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        Revisiting Timing and Decision Modeling for AlloHCT in MDS #bmtsm @DrCCutler https://t.co/DB6B1xU4Z4

    • Mashup Score: 0
      Final outcomes from a phase 2 trial of posoleucel in allogeneic hematopoietic cell transplant recipients - 10 month(s) ago

      Key PointsAllogeneic hematopoietic cell transplant recipients are at risk of clinically significant viral infections due to lack of T-cell immunity.The mul

      Source: ashpublications.org
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        The multivirus-specific T-cell therapy, posoleucel, post-alloHCT. N=26, 3 (12%) had clinically significant infections in first 100 days #bmtsm @BloodAdvances https://t.co/a9KfnczLTi https://t.co/b7cXnMocFl

    • Mashup Score: 8
      HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation - 10 month(s) ago

      Key PointsThis trial used a class I–restricted TCR and a CD8 coreceptor to enable antigen–specific CD8+ and CD4+ T-cell function.Primary end points of feas

      Source: ashpublications.org
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after HCT. Primary end points (feasibility and tolerability) were met in a phase 1 clinical trial of HA-1 TCR-T #bmtsm @BloodJournal https://t.co/svMkMj0VwB

    • Mashup Score: 61
      How I diagnose and treat organizing pneumonia in hematopoietic cell transplant recipients - 10 month(s) ago

      Organizing pneumonia (OP) after allogeneic hematopoietic stem cell transplant (HCT OP) is a major cause of severe morbidity and mortality and is usually as

      Source: ashpublications.org
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        How I diagnose and treat organizing pneumonia in hematopoietic cell transplant recipients #bmtsm @BloodJournal @ajaysheshadri https://t.co/Vgyo14jHnV

    • Mashup Score: 9
      New insights into pregnancy after stem-cell transplantation - 10 month(s) ago

      Many people diagnosed with haematological malignancies or who undergo a haematopoietic stem-cell transplantation (HSCT) must face the impact of their treatment on their future fertility. A new German registry study provides insight into the likelihood of pregnancy and live birth in 2654 women aged 18–40 years who had had an allogeneic HSCT to treat a range of conditions. 50 women had 74 pregnancies, and the annual first birth rate in recipients of an HSCT was 6-times lower than that of the general population at 0·45% (95% CI 0·31–0·59); however, 39 (72%) of 54 pregnancies occurred spontaneously without the need for assistive reproductive technology, providing evidence that pregnancy is possible after this treatment.

      Source: www.thelancet.com
      Categories: General Medicine News, Hem/Oncs
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      • Profile photo of 	Transplant_Doc
        Transplant_Doc

        New insights into pregnancy after stem-cell transplantation @TheLancetHaem #bmtsm https://t.co/XwINK9iJ9M

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