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Mashup Score: 3DCEG Fellowships and Training - 1 year(s) ago
DCEG fellowships and training in cancer epidemiology and genetics includes robust professional development, mentoring, and competitive stipends
Source: National Cancer InstituteCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 1Statistics in Oncology - 2 year(s) ago
© 2022 by American Society of Clinical OncologyConception and design: All authorsCollection and assembly of data: All authorsData analysis and interpretation: All authorsManuscript writing: All authorsFinal approval of manuscript: All authorsAccountable for all aspects of the work: All authorsAUTHORS’ DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTStatistics in OncologyThe following represents…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🗒️ #JCO #Review: Statistics in Oncology https://t.co/dfYRtOXq0T @AlexiaIasonos #biostatistics
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Mashup Score: 1Improving Dose-Optimization Processes Used in Oncology Drug Development to Minimize Toxicity and Maximize Benefit to Patients - 2 year(s) ago
This review highlights strategies to integrate dose optimization into premarketing drug development and discusses the underlying statistical principles. Poor dose optimization can have negative consequences for patients, most commonly because of toxicity, including poor quality of life, reduced effectiveness because of inability of patients to stay on current therapy or receive subsequent therapy…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🗒️ #JCO #Review: Improving dose-optimization processes used in oncology #DrugDevelopment to minimize toxicity and maximize benefit to patients ➡️ https://t.co/kRHHtlwxNo #biostatistics https://t.co/fEyhk0aEhI
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Mashup Score: 0Efficient estimation of SNP heritability using Gaussian predictive process in large scale cohort studies - 2 year(s) ago
Author summary In recent years, there is an increased interest of estimating heritability from genome-wide SNP data in large scale cohort studies. Here, we propose the PredLMM, a computationally rapid and memory-efficient linear mixed model for heritability estimation. The proposed approach can estimate SNP heritability on Biobank-scale datasets in a fraction of time compared to the existing…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
Seal et al present PredLMM: a computationally rapid and memory-efficient linear mixed model for #heritability estimation They demonstrate the method by estimating heritability for quantitative traits using #UKBioBank data #Biostatistics #Genetics https://t.co/BJ3UnRznEb
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Mashup Score: 1Impact of nonrandom selection mechanisms on the causal effect estimation for two-sample Mendelian randomization methods - 2 year(s) ago
Author summary It is well known that nonrandom selection in one-sample Mendelian Randomization (MR) can result in biased estimates and inflated type I error rates. Actually, two-sample MR analyses are more prone to be affected by nonrandom selection than one-sample MR analyses, because two samples for genome-wide association studies (GWAS) may be selected each under different mechanisms from the…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
New research on #MendelianRandomization: Yu et al use simulations to reveal how nonrandom selection in MR analyses can cause bias and type I error They compare how nonrandom selection affects 8 different MR methods #genetics #biostatistics https://t.co/7Hhl8oYlbJ
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Mashup Score: 1Ready for a Fellowship in Cancer Epidemiology and Genetics? - 2 year(s) ago
NCI’s Division of Cancer Epidemiology and Genetics offers one of the largest training programs in cancer epidemiology. As a fellow, you’ll work with cancer e…
Source: YouTubeCategories: Genetics, Latest HeadlinesTweet-
Happening NOW 3pm-4:30: Come visit DCEG's booth with @DianeWigfield to learn more about #postdoc #fellowships in #epidemiology #biostatistics #genetics and more at the @NIH Graduate and Professional School Fair #GPfair22 Learn about fellowships in DCEG: https://t.co/pJzAEKuUaO
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Mashup Score: 0
Author summary An effective approach to study the genetic basis of complex diseases is to assess the associations between genetic variants and gene expression. The statistical power to detect such associations can be improved by using gene expression measurement for each parental allele, though with the price of higher computational cost. We have developed a new method to improve the…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
Zhabotynsky et al present geoP: a computationally efficient method to estimate permutation p-values geoP makes it feasible to perform eQTL mapping with allele-specific gene expression counts for large cohorts #biostatistics #Genetics https://t.co/Fidt8DiE8o
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Mashup Score: 0THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data - 2 year(s) ago
Author summary Hi-C data is used to understand how chromosomes are ordered in a cell. Often, this data is made up of different kinds of cells. Usually, we do not know the number of each kind of cell in the data. When we study Hi-C data, we must learn which part of the data comes from each kind of cell. If not, what we learn in our study might be wrong. As of now, there is no such approach that…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
Rowland et al present THUNDER: an unsupervised deconvolution method for inferring cell type composition from bulk Hi-C data THUNDER can aide the study of cell-type-specificity of the #chromatin interactome #Genomics #biostatistics #Genetics https://t.co/fXsfooZ3JG
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Mashup Score: 1Impact of nonrandom selection mechanisms on the causal effect estimation for two-sample Mendelian randomization methods - 2 year(s) ago
Author summary It is well known that nonrandom selection in one-sample Mendelian Randomization (MR) can result in biased estimates and inflated type I error rates. Actually, two-sample MR analyses are more prone to be affected by nonrandom selection than one-sample MR analyses, because two samples for genome-wide association studies (GWAS) may be selected each under different mechanisms from the…
Source: journals.plos.orgCategories: Genetics, Latest HeadlinesTweet-
New research on #MendelianRandomization: Yu et al use simulations to reveal how nonrandom selection in MR analyses can cause bias and type I error They compare how nonrandom selection affects 8 different MR methods #genetics #biostatistics https://t.co/7Hhl8oGKkb
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Mashup Score: 1Apply for Fellowships - 2 year(s) ago
Postdoctoral, predoctoral and postbaccalaureate applications are accepted from prospective trainees on a rolling basis. Additionally, some investigators post ‘job ads’ for specific training opportunities. Learn more about eligibility requirements and instructions on how to apply.
Source: National Cancer InstituteCategories: Genetics, Latest HeadlinesTweet-
Looking for a #postdoc fellowship in #cancer #epi, #biostatistics, or #genetics? See a list of some of the current openings at DCEG: https://t.co/V2LpOoT62r #NCRM22
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Make your career a priority this #NewYear! Find a fellowship in #CancerResearch #epidemiology #genetics #biostatistics: https://t.co/pdf88huTuG #EpiTwitter @UNCpublichealth @umichsph @YaleSPH @uabSOPH @UCLAFSPH @uscphs @PittPubHealth @TAMU_SPH @UMDPublicHealth @TulaneSPHTM