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bioRxiv# biorxiv
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bioRxivVariant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice - 8 hours
Mashup Score:16
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a global pandemic that has led to more than 2.8 million deaths...
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Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice https://t.co/kW7hqmKl0l #bioRxiv - view on twitter
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bioRxivLong-read whole genome analysis of human single cells - 9 hours
Mashup Score:15
With long-read sequencing we have entered an era where individual genomes are routinely assembled to near-completion and where complex genetic variation can efficiently be...
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Long-read whole genome analysis of human single cells https://t.co/uO0pwqIYVB #bioRxiv - view on twitter
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bioRxivWhy most Principal Component Analyses (PCA) in population genetic studies are wrong - 1 day
Mashup Score:15
Principal Component Analysis (PCA) is a multivariate analysis that allows reduction of the complexity of datasets while preserving data’s covariance and visualizing the information...
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Why most Principal Component Analyses (PCA) in population genetic studies are wrong https://t.co/zzuBhwa7fx #bioRxiv - view on twitter
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bioRxivPrevious studies suggested that the SARS-CoV-2 virus may gain access to the brain by using a route along the olfactory nerve. However, there is...
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Expression of the ACE2 virus entry protein in the nervus terminalis suggests an alternative route for brain infection in COVID-19 https://t.co/FgVdWnMCgP #bioRxiv - view on twitter
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bioRxivAs (generalized) linear mixed-effects models (GLMMs) have become a widespread tool in ecology, the need to guide the use of such tools is increasingly...
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Using random effects in generalized linear mixed-effects models: assessing a common "rule of thumb" https://t.co/cdTsNuPl6W #bioRxiv - view on twitter
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bioRxivMaternal obesity during pregnancy has immediate and long-term detrimental effects on the offspring heart. In this study, we characterized the cardiac and circulatory lipid...
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Maternal diet-induced obesity during pregnancy alters lipid supply to fetuses and changes the cardiac tissue lipidome in a sex- dependent manner https://t.co/pQWsBPOyjT #bioRxiv - view on twitter
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bioRxivBACKGROUND: Anterior cruciate ligament rupture (ACLR) is a well-known risk factor for the development of post-traumatic osteoarthritis (PTOA). While clinical and pre-clinical studies have...
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Early Patellofemoral Cartilage and Bone Degeneration in a Rat Model of Noninvasive Anterior Cruciate Ligament Rupture https://t.co/nL9QJTCAnv #bioRxiv - view on twitter
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bioRxivElevated anti-SARS-CoV-2 antibodies and IL-6, IL-8, MIP-1β, early predictors of severe COVID-19. - 7 hours
Mashup Score:4
Background: Viral and host immune kinetics during acute COVID-19 and after remission of acute symptoms need better characterization. Methods: SARS-CoV-2 RNA, anti-SARS-CoV-2 IgA, IgM,...
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Elevated anti-SARS-CoV-2 antibodies and IL-6, IL-8, MIP-1β, early predictors of severe COVID-19. https://t.co/yj47hFqPVU #bioRxiv - view on twitter
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bioRxivShank proteins are major scaffolds of the postsynaptic density of excitatory synapses. Mutations in SHANK genes are associated with autism and intellectual disability. The...
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Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders. https://t.co/lkgULVAxLz #bioRxiv - view on twitter
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Knock-in of precise point mutations into protein-coding genes has been one of the earliest and most important applications of Clustered Regularly Interspaced Palindromic Repeats...
CRISPR Knock-in Designer: automatic oligonucleotide design software to introduce point mutations using CRISPR/Cas9 https://t.co/0jxVRiQ1ft #bioRxiv - view on twitter