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mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants

posted 2 days

Mashup Score: 32

bioRxiv - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative infection of a global pandemic that has led to more than 2 million deaths worldwide....

Variant and mutation analysis of SARS-CoV-2 genomes isolated from the Kingdom of Bahrain

posted 15 hours

Mashup Score: 3

bioRxiv - The challenges imposed by the ongoing outbreak of severe acute respiratory syndrome coronavirus-2 affects every aspect of our modern world, ranging from our health...

A novel SARS-CoV-2 related coronavirus in bats from Cambodia

posted 15 hours

Mashup Score: 3

bioRxiv - Knowledge of the origin and reservoir of the coronavirus responsible for the ongoing COVID-19 pandemic is still fragmentary. To date, the closest relatives to...

PIP2 regulation of TRPC5 channel activation and desensitization

posted 11 hours

Mashup Score: 3

bioRxiv - Transient receptor potential canonical type 5 (TRPC5) channels are expressed in the brain and kidney, and have been identified as promising therapeutic targets whose...

bioRxiv - Changes in a few key transcriptional regulators can lead to different biological states, including cell activation and differentiation, and diseases. Extracting the key gene...

  • RegEnrich: An R package for gene regulator enrichment analysis reveals key role of ETS transcription factor family in interferon signaling https://t.co/qQRnjLT7aB #bioRxiv

bioRxiv - Type I interferons (IFN α/β) play a central role in innate immunity to respiratory viruses, including coronaviruses. Genetic defects in type I interferon signaling...

  • Profiling transcription factor sub-networks in type I interferon signaling and in response to SARS-CoV-2 infection https://t.co/i1wzgSn2RC #bioRxiv

A joint analysis of longevity and age-related disease variants for gene expression association

posted 10 hours

Mashup Score: 2

bioRxiv - A large number of genetic variants associated with human longevity have been reported but how they play their functions remains elusive. We performed an...

Regulatory Modules of Human Thermogenic Adipocytes: Functional Genomics of Meta-Analyses Derived Marker-Genes

posted 19 hours

Mashup Score: 2

bioRxiv - Recently, ProFAT and BATLAS scores have been offered to determine thermogenic status of adipocytes using expression pattern of brown and white marker-genes. In this...

bioRxiv - The yeast Hsp104 protein disaggregase is often used as a reporter for misfolded or damaged protein aggregates and protein quality control and ageing research....

  • Comparison of endogenously expressed fluorescent protein fusions behaviour for protein quality control and cellular aging research https://t.co/17Texg9Cgw #bioRxiv

Personalized Perturbation Profiles Reveal Concordance between Autism Blood Transcriptome Datasets

posted 1 day

Mashup Score: 2

bioRxiv - The complex heterogeneity of Autism Spectrum Disorder (ASD) has made quantifying disease specific molecular changes a challenge. Blood based transcriptomic assays have been performed...