• Mashup Score: 0
    Phase separation in biology - 3 year(s) ago

    A collection of Reviews from Nature Reviews Molecular Cell Biology, and research papers from the Nature journals, on phase separation mechanisms and the roles of biomolecular condensates.

    Source: www.nature.com
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      To further explore the universe of #biomolecularcondensates see this Collection of #Reviews, journal clubs and selected research articles @NaturePortfolio highlighting recent progress in mechanisms and roles of #LiquidLiquidPhaseSeparation in biology https://t.co/xog6aCtEpR https://t.co/MLMZJAuDie

  • Mashup Score: 2
    Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing - 3 year(s) ago

    Biomolecular condensates, which form via liquid−liquid phase separation in a tightly regulated manner, have fundamental roles in cellular organization and physiology. Recent studies provide insight into how cellular stress, ageing-related loss of homeostasis and a decline in protein quality control may contribute to the formation of aberrant, disease-causing condensates.

    Source: Nature Reviews Molecular Cell Biology
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      A fantastic #Review by Tony Hyman and Simon Alberti on cellular regulation of biomolecular condensates and how it goes awry in disease @HymanLab @tudresden_de @mpicbg @BIOTEC_TUD #phaseseparation #biomolecularcondensates https://t.co/lSUXa3E3WZ https://t.co/dLqEIlJezU

  • Mashup Score: 1
    A framework for understanding the functions of biomolecular condensates across scales - 4 year(s) ago

    Biomolecular condensates are membraneless molecular assemblies formed via liquid–liquid phase separation. They have a plethora of roles, ranging from controlling biochemical reactions to regulating cell organization and cell function. This article provides a framework for the study of condensate functions across these cellular length scales, offering to bring new understanding of biological…

    Source: Nature Reviews Molecular Cell Biology
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      A must read Roadmap by Mike Rosen and co: A framework for understanding the functions of biomolecular condensates across scales @a_s_lyon @UTSWNews #PhaseSeparation #LLPS #BiomolecularCondensates https://t.co/tFxhDPvfiB !FREE! pdf: https://t.co/QMefoHhi3Z https://t.co/THymOjOY15

  • Mashup Score: 3
    RNA contributions to the form and function of biomolecular condensates - 4 year(s) ago

    Recent studies have highlighted the contribution of RNA to cellular liquid–liquid phase separation and condensate formation. RNA features modulate the composition and biophysical properties of RNA–protein condensates, which have various cellular functions, including RNA transport and localization, supporting catalytic processes and responding to stress.

    Source: Nature Reviews Molecular Cell Biology
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      Hot topic! #Review by Amy Gladfelter @UNC explaining the role of RNAs in the formation of biomolecular condensates #liquidliquidphaseseparation #PhaseSeparation #biomolecularcondensates Check it out here: https://t.co/aHbQgaMuyp https://t.co/tZ2RnuX7KF