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Mashup Score: 14
Objectives To determine the cumulative incidence and identify the factors associated with difficult-to-treat axial spondyloarthritis (D2T-axSpA) in French patients newly benefiting from the French ‘long-term illness’ (LTI) social security scheme for axial spondyloarthritis (axSpA). Methods This national cohort study was based on the French National Medico-Administrative Database, SNDS, which contains data on hospitalisation, LTI and outpatient care consumption. All French patients newly receiving LTI benefits for ankylosing spondylitis (AS) between 2010 and 2013 were included in the study. In France, LTI is required to access biological/targeted synthetic DMARDs (b/tsDMARDs). The follow-up period ended on 31 December 2018. So-called D2T-axSpA was defined as the failure of three b/tsDMARDs or of two b/tsDMARDs with different modes of action. Comorbidities and extra-musculoskeletal manifestations were identified using previously described algorithms. Characteristics were compared between
Source: rmdopen.bmj.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 3
Objectives Bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL-17A, has demonstrated superior efficacy versus placebo in patients with non-radiographic (nr-) and radiographic (r-) axial spondyloarthritis (axSpA) at Week 16. Here, the objective is to report the efficacy and safety of BKZ at Week 52. Methods BE MOBILE 1 (nr-axSpA; [NCT03928704][1]) and BE MOBILE 2 (r-axSpA; [NCT03928743][2]) comprised a 16-week, double-blind, placebo-controlled period, then a 36-week maintenance period. From Week 16, all patients received subcutaneous BKZ 160 mg every 4 weeks. Results Improvements versus placebo in Assessment of SpondyloArthritis International Society ≥40% response (primary endpoint), Ankylosing Spondylitis Disease Activity Score, high-sensitivity C-reactive protein levels and MRI inflammation of the sacroiliac joints/spine at Week 16 were sustained to Week 52 in BKZ-randomised patients. At Week 52, responses of patients switchin
Source: ard.bmj.comCategories: Latest Headlines, RheumatologyTweet-
Starting the week with two #Bimekizumab (dual IL-17A & IL-17F inhibitor) studies 1️⃣ 52-week data in #axSpA BE-MOBILE 1 (nr) & 2 (r-axSpA) ▶️ sustained efficacy across axSpA ▶️ safety profile consistent with known safety 👉 https://t.co/u2ocSycU1o @XBaraliakos @LianneGensler
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Mashup Score: 1Act Now to Protect Patient Access to Healthcare - 7 month(s) ago
Great news! Federal Court Ruling on Copay Accumulators is a Win for Patients.Recently, in a major victory for patients who depend on prescription drugs to manage their health conditions, a federal judge struck down a rule that allowed health…
Source: www.votervoice.netCategories: Latest Headlines, RheumatologyTweet-
Great news for the #spondylitis community! On Sept. 29th, there was a major legal victory for patients who depend on prescription drugs. Urge HHS not to appeal this important legal decision that protects patient access to healthcare and treatments:https://t.co/cGHZXmadkB #axspa https://t.co/NTl9z603M0
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Mashup Score: 0Why are the classification and diagnosis of axial spondyloarthritis sometimes so difficult? - 7 month(s) ago
Jürgen Braun; Why are the classification and diagnosis of axial spondyloarthritis sometimes so difficult?, Rheumatology, , kead532, https://doi.org/10.1093/rheu
Source: academic.oup.comCategories: Latest Headlines, RheumatologyTweet-
Why are the classification & diagnosis of #axSpA sometimes so difficult? Jürgen Braun discusses the topic in light of a particularly complex patient 👇 https://t.co/cgjFjM1XZQ
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Mashup Score: 2Heart Health and Axial Spondyloarthritis: Outlook, Risks, and Helpful Tips - Spondylitis Association of America - Ankylosing Spondylitis - 7 month(s) ago
In this article we’ll look at the relationship between axSpA and the heart, and how you can monitor and improve your heart health with axSpA.
Source: spondylitis.orgCategories: Latest Headlines, RheumatologyTweet-
Did you know? Axial spondyloarthritis can impact more than just your joints. It's associated with an increased risk of heart disease. Discover the link between axSpA & cardiovascular health by clicking the link below. https://t.co/5qmH1rj5Sp #HeartHealth #axSpA #WorldHeartDay https://t.co/9MFpNlemPo
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Mashup Score: 0Diet's Effect on Spondylitis Symptoms | SPONDYLITIS.ORG - 7 month(s) ago
Some people find that certain foods trigger changes in symptoms either for the better or the worse. Read more about how your diet can affect your spondylitis.
Source: spondylitis.orgCategories: Latest Headlines, RheumatologyTweet-
Managing pain goes beyond medication. #Nutrition plays a crucial role too! Boost your pain management strategy with antioxidants, omega-3s, and a balanced diet. Learn more about pain management through nutrition: https://t.co/sQYusP2N9T #PainAwareness #ChronicPain #AxSpA https://t.co/Yzu6cEmWqq
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Mashup Score: 1
A new consensus definition for early axial spondyloarthritis indicates disease that has manifested symptoms for less than 2 years, according to a recommendation published in Annals of the Rheumatic Diseases.
Source: www.healio.comCategories: Latest Headlines, RheumatologyTweet-
“It is now proposed that going forward, this definition should be used for research studies addressing early #axSpA.” #RheumTwitter #MedTwitter https://t.co/RCAGSovWNx
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Mashup Score: 0Diagnosing Chronic Back Pain: When to Suspect AxSpA - 9 month(s) ago
Expert tips for identifying people with axial spondyloarthritis in primary care practice.
Source: www.medscape.comCategories: General Medicine News, Latest HeadlinesTweet-
Expert tips for identifying people with axial spondyloarthritis in primary care practice. #AxSpA #backpain #MedX https://t.co/4lH71KzH4c https://t.co/gK4KXivFNs
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Mashup Score: 0
The median central sensitization, frequency of neuropathic pain, and frequency of fibromyalgia diagnosis were higher in patients with axSpA when compared with controls.
Source: www.hcplive.comCategories: Latest Headlines, RheumatologyTweet-
The median central sensitization, frequency of neuropathic pain, and frequency of #fibromyalgia diagnosis were higher in patients with #axSpA when compared with controls. https://t.co/kex7HXr1NH https://t.co/K1FtxoOCqH
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Mashup Score: 1Apply for the Early Career Investigator Award - Spondylitis Association of America - Ankylosing Spondylitis - 10 month(s) ago
The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis As part of our ongoing mission to expand horizons in spondyloarthritis research, the Spondylitis Association of America hopes to encourage new, upcoming rheumatologists and researchers to focus on the future of treatment and research in ankylosing spondylitis and related diseases. About the Award This is …
Categories: Latest Headlines, RheumatologyTweet-
Applications are now open for the SAA/Bruckel Early Career Investigator Award. This $30k grant is awarded to early-career researchers in #axpsa. Apply today at https://t.co/Jk5OV44HIs #axspa #rheumatology https://t.co/yueY2o2Mhh
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Difficult-to-treat #axSpA 🔺 National cohort: French National Medico-Administrative Database, SNDS 🔺 22932 pts 🔺D2T-axSpA affects one in five patients exposed to bDMARDs ➕ more in women, psoriasis, peripheral involvement, comorbidities 👉 https://t.co/qJuQb49RS7 https://t.co/QvBDIwjQw2