-
Mashup Score: 1Volume 22 Issue 11, November 2021 - 3 year(s) ago
Volume 22 Issue 11, November 2021
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet
-
Mashup Score: 2Machinery, regulation and pathophysiological implications of autophagosome maturation - Nature Reviews Molecular Cell Biology - 3 year(s) ago
Following their biogenesis, autophagosomes undergo maturation into degradative autolysosomes by fusing with late endosomes/lysosomes. This process — involving an array of molecular regulators of membrane dynamics — is essential for autophagic degradation, and its deregulation can lead to disease, including neurodegeneration, muscle diseases and cancer, and propagation of pathogens.
Categories: Allergy-Immunology, Latest HeadlinesTweet
-
Mashup Score: 14Machinery, regulation and pathophysiological implications of autophagosome maturation - Nature Reviews Molecular Cell Biology - 3 year(s) ago
Following their biogenesis, autophagosomes undergo maturation into degradative autolysosomes by fusing with late endosomes/lysosomes. This process — involving an array of molecular regulators of membrane dynamics — is essential for autophagic degradation, and its deregulation can lead to disease, including neurodegeneration, muscle diseases and cancer, and propagation of pathogens.
Categories: Allergy-Immunology, Latest HeadlinesTweet
-
Mashup Score: 15Mechanisms governing autophagosome biogenesis - 4 year(s) ago
Autophagy involves engulfment of cellular components into double-membrane vesicles called autophagosomes. The biogenesis of autophagosomes requires the cooperation of multiple proteins and lipids from various membrane sources. Our understanding of the molecular mechanisms of the initiation, growth, bending and closure of autophagosomal membranes is expanding at a rapid pace.
Categories: Allergy-Immunology, Latest HeadlinesTweet
-
Mashup Score: 6Mechanisms governing autophagosome biogenesis - 4 year(s) ago
Autophagy involves engulfment of cellular components into double-membrane vesicles called autophagosomes. The biogenesis of autophagosomes requires the cooperation of multiple proteins and lipids from various membrane sources. Our understanding of the molecular mechanisms of the initiation, growth, bending and closure of autophagosomal membranes is expanding at a rapid pace.
Categories: Allergy-Immunology, Latest HeadlinesTweet
-
Mashup Score: 4Volume 21 Issue 8, August 2020 - 4 year(s) ago
Volume 21 Issue 8, August 2020
Source: www.nature.comCategories: Allergy-Immunology, Latest HeadlinesTweet
November issue @NatRevMCB is now available! https://t.co/H1bYw62LTT Topics: underpinnings of #insulinresistance, #musclediseases and #autophagosome maturation. On the cover, ‘Skeletal muscle fibres’ inspired by Review from Dowling, Weihl and Spencer https://t.co/JH5RFkVBM1 https://t.co/HngCGdXy6D