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Mashup Score: 2Impact of CD70 on aGVHD prevention and treatment - 7 month(s) ago
Verma K, Croft W, Margielewska-Davies S, et al. CD70 Identifies Alloreactive T Cells and Represents a Potential Target for Prevention and Treatment of Acute GVHD. Blood Advances. 2024; (doi:…
Source: www.astct.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 0Unconventional T Cells Influence Clinical Outcome After Allogeneic Hematopoietic Cell Transplantation - 8 month(s) ago
Researchers from the Centre de Recherche Saint-Antoine (CRSA) at Sorbonne Université in France investigated the impact of early recovery of mucosal-associated invariant T (MAIT) cells and…
Source: www.astct.orgCategories: General Medicine News, Oncologists1Tweet-
Researchers from the Centre de Recherche Saint-Antoine (CRSA) at Sorbonne Université found early recovery & high frequencies of MAIT plus Vδ2+CD26+ T cells were associated with improved clinical outcomes after #alloHCT. Read more on Nucleus: https://t.co/Q6aardrnZh https://t.co/F5AL7UKCVT
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Mashup Score: 5Allogeneic Hematopoietic Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm: a CIBMTR analysis - 2 year(s) ago
Key Points. Age 60 or older and remission status at time of allo-HCT (CR2/PIF/Relapse vs CR1) was predictive of inferior overall survival.Use of myeloablative c
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
How well does Allogeneic Hematopoietic Cell Transplantation #AlloHCT work for Blastic Plasmacytoid Dendritic Cell Neoplasm #BPDCNsm ? Our new @CIBMTR analysis with many outstanding investigators @BloodAdvances @YaleCancer https://t.co/juMTRHAKcW
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Mashup Score: 4
Katie Robinson is a medical writer based in New York. Patients undergoing a human leukocyte antigen (HLA)-matched allogeneic hematopoietic cell transplantation (alloHCT) with reduced-intensity conditioning who received a prophylaxis regimen of cyclophosphamide, tacrolimus, and mycophenolate mofetil had longer graft-versus-host disease (GVHD)-free, relapse-free survival than those who received standard prophylaxis of tacrolimus and methotrexate. These findings from a phase III study were published in the
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
Patients undergoing an #alloHCT with reduced-intensity conditioning had longer GVHD-free and #relapse-free survival with a prophylaxis regimen of cyclophosphamide, tacrolimus, and mycophenolate mofetil than those treated with standard #prophylaxis. https://t.co/IE3sofWixi
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Mashup Score: 0Cyclosporine impact on tolerance induction after allo-HCT - 2 year(s) ago
Senjo H, Harada S, Kubota SI, et al. Calcineurin Inhibitor Inhibits Tolerance Induction by Suppressing Terminal Exhaustion of Donor T Cells After Allo-HCT. Blood. 2023; (doi:…
Source: nucleus.astct.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Researchers may have uncovered why, despite routine prophylaxis, many #alloHCT recipients fail to attain long-term tolerance w/o development of chronic #GVHD, and it has to do with transitory-tex and terminally-tex T cells. Read more on Nucleus: https://t.co/fN4HklI9Je #CARTcells https://t.co/RMEhTBKflg
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Mashup Score: 0
Findings from a phase 3 trial published in JAMA Oncology suggest allo-HCT may not provide an OS benefit for patients with intermediate-risk acute myeloid leukemia during first complete remission.
Source: www.targetedonc.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
#AlloHCT did not correlate with superior overall survival vs consolidation chemotherapy in patients aged 60 years or younger with intermediate-risk #AML during first complete remission. #leusm https://t.co/3mDQ2PVtQY
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Mashup Score: 0
A cohort study identified an association between exposure to several commonly used antibiotics and acute GVHD in patients who underwent allogeneic hematopoietic cell transplantation.
Source: Oncology Nurse AdvisorCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Several antibiotics were found to associate with increased rates of acute #graftvsHost disease in patients who have recently undergone #alloHCT. Published in @JAMANetworkOpen. https://t.co/EiVseVuPx5 #aGVHD
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Mashup Score: 1Maintenance with ivosidenib post-HCT in IDH1-mutated AML - 2 year(s) ago
Fathi AT, Kim HT, Soiffer RJ, et al. Multi-Center Phase I Trial of Ivosidenib as Maintenance Treatment Following Allogeneic Hematopoietic Cell Transplantation for IDH1-Mutated Acute Myeloid Leukemia. Clinical Cancer Research. 2023; (doi: 10.1158/1078-0432.CCR-23-0182). A Phase I trial testing the isocitrate dehydrogenase 1 (IDH1) inhibitor ivosidenib as maintenance therapy in patients with…
Source: ASTCT NucleusCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
A Phase I trial testing isocitrate dehydrogenase 1 (IDH1) inhibitor ivosidenib as maintenance therapy in patients with IDH1-mutated #AML following #alloHCT found that it was safe and well-tolerated. Read more about the findings on Nucleus: https://t.co/q0mQpSStBU #Leusm https://t.co/R7O1kRG2n9
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Mashup Score: 2Value of DNA sequencing pre-HCT for AML patients - 2 year(s) ago
Dillon LW, Gui G, Page KM, et al. DNA Sequencing to Detect Residual Disease in Adults with Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant. JAMA. 2023; 329 (9): 745 (doi: 10.1001/jama.2023.1363). In patients with acute myeloid leukemia (AML) in first remission before undergoing allogeneic hematopoietic cell transplant, new research shows poorer outcomes for individuals with…
Source: ASTCT NucleusCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
A new observational study examined DNA sequencing on pre-transplant blood of adult patients who had received intial #alloHCT during first complete remission for #AML. Read more about the findings and DNA variants: https://t.co/FTr5f7vFoS #Leusm https://t.co/VWJbqZuRo5
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Mashup Score: 3
Background: Allogeneic haematopoietic cell transplantation (alloHCT) is a life-saving procedure for many patients with haematological disease. However, its toxi
Source: papers.ssrn.comCategories: Hematologists1, Latest HeadlinesTweet-
Great effort with @TheEBMT @ICO_oncologia @HHospitalet @idibell_cat in using #ArtificialIntelligence methodology for creating a prognostic score for #alloHCT The preprint version of our last work is here👇👇👇 https://t.co/GJeqsbqOkq Waiting for the incoming publication!
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Researchers report that CD70 may be a promising target for preventing acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (#alloHCT) or treating it once it has developed. Read more on Nucleus: https://t.co/EdrfGL1skw https://t.co/yJq16Sxhll