• Mashup Score: 9

    Nonrandomized 12-year data do not provide hard conclusions about testosterone benefit vs risk for men with low T and diabetes; one RCT has been published, but the jury is still out on safety.

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    • A study of men with T2D and low testosterone suggests that patients who receive up to 12 years of testosterone injections every 3 months may improve glycemic control. https://t.co/r3W29MfTcC #ADA2021

  • Mashup Score: 6

    The FDA released new draft guidance for the evaluation of type 2 diabetes drugs. Dr John Buse discusses the impact this could have on clinical trials and the medications we might see from the changes.

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    • The 2020 draft guidance from the FDA surrounding cardiovascular trials in people with diabetes provides a lot more flexibility now. https://t.co/7RM7VPO8DL #ADA2021 https://t.co/146sX3bQMp

  • Mashup Score: 0

    ‘A number of clinical trials of antidiabetic pharmacologic agents in diabetic youth have been completed, demonstrating safety and efficacy, and a wider availability of agents is finally in sight,’ said an expert.

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    • There are limited treatment options for children and youth with #T2D, but a few novel therapies beyond metformin are on the horizon, say experts. https://t.co/L2M4XIUM3I #ADA2021 https://t.co/YH1ki1ZTdN

  • Mashup Score: 4

    Simultaneous pancreas-kidney transplants are increasingly performed in patients with type 2 diabetes and chronic kidney disease, who now account for about 20% of all pancreas transplants in the US.

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    • Roughly 50%-60% of candidates on the kidney transplant waiting list also have T2D so the fact that simultaneous pancreas-kidney transplants are increasingly performed, isn’t such a crazy idea anymore. https://t.co/qroRV1Lt5V #ADA2021

  • Mashup Score: 0

    ‘A number of clinical trials of antidiabetic pharmacologic agents in diabetic youth have been completed, demonstrating safety and efficacy, and a wider availability of agents is finally in sight,’ said an expert.

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    • Youth with T2D have limited treatment options besides taking #metformin, but new clinical trials of antidiabetic pharmacologic agents are bringing options. https://t.co/pSYd1CpmAg #ADA2021