Spontaneous Intracerebral Hemorrhage in Men vs Women: Which Sex Has Better Outcomes?
Men vs women with spontaneous intracerebral hemorrhage (ICH) have a higher risk for deep bleeds but a lower risk for poor outcomes.
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EAN Advocacy Training
Under the umbrella of the Brain Health Mission, and as a way to support its 48 National Neurological Societies , EAN has developed online Advocacy…
The onset presentation of multiple sclerosis differs in Hispanic/Latinx Americans compared with non-Hispanic White Americans – Farren BS Briggs, Devon S Conway, Carrie M Hersh, Kathryn C Fitzgerald, Ellen Mowry, Jeffrey A Cohen, Daniel Ontaneda, 2024
Background: Little is known about how multiple sclerosis (MS) presents in Hispanic/Latinx (HL) people with MS (pwMS). Objective: Compare age at onset (AAO) and …
Recommendations for essential medicines for multiple sclerosis in low-resource settings – Deanna Saylor, Nick Rijke, Jennifer McDonell, Joanna Laurson-Doube, Jagannadha Avasarala, Elisa Baldin, Tapas K Banerjee, Ivana Bogdanovic, Riley Bove, DK Chawla, Kathleen Costello, Cinzia Del Giovane, Najoua E
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Ofatumumab-exposed breastfeeding in multiple sclerosis patients – Laura Witt, Karen Dost-Kovalsky, Natalia Friedmann, Nadine Bast, Sabrina Haben, Theresa Oganowski, Ralf Gold, Kerstin Hellwig, Sandra Thiel, 2025
Background: In Europe, ofatumumab is approved for breastfeeding, but data on its transfer into breast milk and clinical experience are lacking. Objective: To an…
Real-world evidence of ocrelizumab in Chilean patients with multiple sclerosis – Adolfo del Canto, Claudia Cárcamo, Lorena Garcia, Ester Aylwin, Lukas Jürgensen-Heinrich, Ignacio Guzman-Carcamo, Juan de la Barra, Leticia Gutierrez-Calquin, Antonia Barrera-Hormazabal, Juan Pablo Cruz, Sebastián Bravo
Background: Real-world studies are needed to expand our knowledge concerning populations underrepresented in clinical trials. Objective: This study aimed to eva…
A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD
Nature Communications – An expansion of a hexanucleotide repeat in the C9ORF72 gene can cause ALS. Here, the authors develop a high-fidelity RNA-targeting CRISPR system…
Modulating mTOR-dependent astrocyte substate transitions to alleviate neurodegeneration
Nature Aging – The authors show that neuroprotective and neurotoxic astrocytes represent transitional cellular substates present during neuroinflammation and that targeting mTOR in astrocytes…
De-escalating and discontinuing disease-modifying therapies in multiple sclerosis
The benefits of early initiation of disease-modifying therapy in multiple sclerosis are well-established; however, the issue of when and how to de-escalate
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FSHD type 1 shows marked variability in age at onset and disease severity. Zheng et al. reveal independent contributions of genetic characteristics, includ
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