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Mashup Score: 213
Exagamglogene autotemcel (exa-cel) is a nonviral cell therapy designed to reactivate fetal hemoglobin synthesis through ex vivo clustered regularly interspaced short palindromic repeats (CRISPR)–Ca…
Source: www.nejm.orgCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 12Global Health Law for a Safer and Fairer World | NEJM - 9 hour(s) ago
After Covid-19, the global health community must address major gaps in global preparedness, critical capacities needed for a safer and fairer world, and international instruments required for reali…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 122Trial Update of Pitavastatin to Prevent Cardiovascular Events in HIV Infection | NEJM - 10 hour(s) ago
In the final results of a randomized trial involving patients with HIV infection, pitavastatin reduced the incidence of adverse cardiovascular events at 5.6 years of follow-up as compared with …
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 794Cryptococcal Disease in Diverse Hosts | NEJM - 12 hour(s) ago
Cryptococcus accounts for up to 180,000 deaths annually and 68% of HIV-related meningitis cases. The authors discuss diagnostic, preventive, and therapeutic strategies and the pathophysiological ro…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet-
Cryptococcus accounts for up to 180,000 deaths annually and 68% of HIV-related meningitis cases. The authors of a new review discuss diagnostic, preventive, and therapeutic strategies and the pathophysiological role of inflammatory syndromes. Full review: https://t.co/tXOf7Ra8fN https://t.co/6cnBejvh2x
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Mashup Score: 93The Meat of the Matter | NEJM - 16 hour(s) ago
A 32-year-old woman with no notable medical history presented to the ED with a 10-day history of shortness of breath, fevers, and cough. She also reported sore throat and myalgias but no chest pain.
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 2Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Dairy Farm Worker | NEJM - 17 hour(s) ago
A highly pathogenic avian influenza A(H5N1) virus infection was identified in a dairy farm worker in Texas. This pathogen has been reported in multiple dairy herds in several states.
Source: www.nejm.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 65
Congenital thrombotic thrombocytopenic purpura (TTP) results from severe hereditary deficiency of ADAMTS13. The efficacy and safety of recombinant ADAMTS13 and standard therapy (plasma-derived prod…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet-
Congenital thrombotic thrombocytopenic purpura results from hereditary deficiency of ADAMTS13. Prophylactic administration of recombinant ADAMTS13 achieved normal blood levels with limited toxicity and no neutralizing antibodies. Full cTTP trial results: https://t.co/BzPzKIwfdP https://t.co/hT9TdUgCnd
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Mashup Score: 71The Repair of Hiatus Hernia of the Diaphragm by the Supradiaphragmatic Approach | NEJM - 1 day(s) ago
THE use of the supradiaphragmatic approach in the treatment of esophageal hiatus hernia converts what, in the majority of cases, would be a difficult and formidable procedure into one that can be a…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 15Acute Promyelocytic Leukemia | NEJM - 1 day(s) ago
A 47-year-old man presented with 2-day history of weakness and fever. Laboratory studies showed pancytopenia. A bone marrow biopsy showed promyelocytes with abundant intracellular rods.
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 15Acute Promyelocytic Leukemia | NEJM - 2 day(s) ago
A 47-year-old man presented with 2-day history of weakness and fever. Laboratory studies showed pancytopenia. A bone marrow biopsy showed promyelocytes with abundant intracellular rods.
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
Of 35 patients with transfusion-dependent β-thalassemia treated with gene-edited autologous hematopoietic stem and progenitor cells, 32 had hemoglobin levels maintained without red-cell transfusions for at least 12 consecutive months. Full study results: https://t.co/LiTmJPoyfq https://t.co/KqsJLFrQJG