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Mashup Score: 13Sequential CD7 CAR T-Cell Therapy and Allogeneic HSCT without GVHD Prophylaxis | NEJM - 1 hour(s) ago
Patients with relapsed or refractory hematologic cancers have a poor prognosis. Chimeric antigen receptor (CAR) T-cell therapy as a bridge to allogeneic hematopoietic stem-cell transplantation (HSC…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 0Age-Related Hearing Loss | NEJM - 2 hour(s) ago
Hearing progressively declines with age, manifesting initially as difficulty understanding speech in background noise and detrimentally affecting social functioning. Strategies and technologies can…
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 24
The autologous cellular therapy exagamglogene autotemcel is generated by editing an erythroid-specific enhancer of BCL11A. Could another site be edited unintentionally? This study gauged the likeli…
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet-
The autologous cellular therapy exagamglogene autotemcel is generated by editing an erythroid-specific enhancer of BCL11A. Could another site be edited unintentionally? This study gauged the likelihood of off-target editing. Read the full correspondence: https://t.co/jX714YVL3A https://t.co/NT58JhlbOM
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Mashup Score: 30FFR-Guided Complete PCI for STEMI | NEJM - 20 hour(s) ago
Quick Take Video Summary from The New England Journal of Medicine — FFR-Guided Complete PCI for STEMI
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 201
Subcutaneous administration of the monoclonal antibody L9LS protected adults against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal antibody administered subcut…
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 559Welcoming the Era of Gene Editing in Medicine | NEJM - 20 hour(s) ago
Recent approvals of exa-cel for treatment of sickle cell disease and transfusion-dependent β-thalassemia mark the dawn of the era of gene editing in medicine. But ensuring access will be challenging.
Source: www.nejm.orgCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 21Small-Bowel Bleeding | NEJM - 22 hour(s) ago
Abdominal pain and large-volume hematochezia developed in a man who was in the hospital for a ruptured cerebral aneurysm. Findings on endoscopy and colonoscopy were unremarkable, so CT angiography …
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 201
Subcutaneous administration of the monoclonal antibody L9LS protected adults against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal antibody administered subcut…
Source: www.nejm.orgCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 380Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine | NEJM - 24 hour(s) ago
Review Article from The New England Journal of Medicine — Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 205Beyond Code Status | NEJM - 1 day(s) ago
Despite being absolutely clear that she wanted a quick, painless end of life, a geriatrician’s elderly mother receives aggressive care. How can we ensure that such patient preferences are honored?
Source: www.nejm.orgCategories: General Medicine News, General HCPsTweet-
Superb and infuriating piece by @UCSF colleague (& great writer) @LouiseAronson about how her mom's clear, documented wish to avoid aggressive care at the end of life was ignored by a medical team locked into a we-did-this-so-we-must-do-that spiral. @NEJM https://t.co/o2qVZIjp4W https://t.co/Lmlxvu7z7w
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Of 10 patients with relapsed or refractory hematologic cancers who received sequential CAR T-cell infusion followed by allogeneic stem-cell transplantation without GVHD prophylaxis, 6 were alive and disease-free at last follow-up. Read the full article: https://t.co/tmurp1z5Fz https://t.co/hlE2JHw8DK