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Mashup Score: 1
This joint expert review by the Obesity Medicine Association (OMA) and National Lipid Association (NLA) provides clinicians an overview of the pathophysiologic and clinical considerations regarding obesity, dyslipidemia, and cardiovascular disease (CVD) risk.
Source: www.lipidjournal.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 0Lipid-lowering optimisation for secondary prevention vascular and diabetic foot patients in a pharmacist-led clinic - 1 month(s) ago
Cardiovascular disease (CVD) is the leading cause of death accounting for a quarter of all deaths in the UK and more than 100,000 hospital admissions1. Stroke causes 38,000 deaths and 100,000 admissions in the UK annually2. Associated healthcare costs are estimated to be £9 billion every year with an overall CVD burden of approximately £19 billion annually3.
Source: www.lipidjournal.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 76Effect of Statin Use on Liver Enzymes and Lipid Profile in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD) - 2 month(s) ago
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease with the prevalence of approximately 30%.1 The prevalence goes up among specific high-risk populations: 30-50% in patients with type 2 diabetes, and 80-90% in patients with obesity.2,3
Source: www.lipidjournal.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 29
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide and especially in low and middle-income countries (LMICs).1 Statins represent a key strategy to prevent dyslipidemia-associated CVD morbidity and mortality, because of their reduction on LDL-cholesterol (LDL-C) concentrations, as well as anti-inflammatory and other plaque-stabilization effects.2-4 Although individuals without previous CVD are at lower absolute risk, at least half of all vascular events occur among them.
Source: www.lipidjournal.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 1Use of Lipid Ratios to Predict Vascular Target Organ Damage in Youth - 3 month(s) ago
Elevated triglycerides (TG) and non-high-density lipoprotein cholesterol with reduced high-density lipoprotein cholesterol (HDL-C), known as combined dyslipidemia (CD)1-4, is increasing with the concomitant increase in rates of childhood obesity. The most recent NHANES data have shown that the prevalence of childhood obesity is up to 19% with an estimated 30-60% of obese youth having CD.2,5 This characteristic pattern of obesity and dyslipidemia has been associated with insulin resistance, metabolic syndrome, and type 2 diabetes (T2D) .
Source: www.lipidjournal.comCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 5Lipid Association of India 2023 update on cardiovascular risk assessment and lipid management in Indian patients: Consensus statement IV - 3 month(s) ago
The epidemiology of atherosclerotic cardiovascular disease (ASCVD) in India differs considerably from the same in Western countries. It is well recognized that Indians develop ASCVD about a decade earlier than the Western populations,1 despite having lower levels of low-density lipoprotein cholesterol (LDL-C). It has been reported that more than 50% of coronary artery disease (CAD)-associated deaths in India occur before the age of 50 years and 25% of myocardial infarctions (MIs) occur before the age of 40 years.
Source: www.lipidjournal.comCategories: General Medicine News, Cardiologists1Tweet
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Mashup Score: 1Fatty acid analysis in serum of patients with elevated lipoprotein(a) and cardiovascular disease undergoing lipoprotein apheresis - 5 month(s) ago
Lipoprotein(a) (Lp(a)) consists of LDL-like particle covalently banded with apolipoprotein (a) [apo(a)]. Apo(a) is encoded by LPA gene localized on chromosome 6q27 and consists of loop-like structures called cringles. KIV-2 copy number variation (from 1 to 40 repeat sequences) polymorphism is the most important predictor of variations in Lp(a) concentration. Small isoforms (≤22 KIV repeats) are related to 4 to 5-fold higher Lp(a) concentrations than large isoforms (>22 KIV). Roeseler at al. reported that 95% patients with CVD undergoing lipoprotein apheresis (LA) therapy expressed at least one small apo(a) isoform.
Source: www.lipidjournal.comCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 0Sex differences in the perception of cardiovascular risk in familial hypercholesterolemia - 7 month(s) ago
Familial Hypercholesterolemia (FH) is one of the most common genetic disorders in humans with a prevalence of 1:311.1 It is an autosomal dominant trait, affecting males and females equally. Loss-of-function variants in the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), or gain-of-function in protein convertase subtilisin/kesin-9 (PCSK9) genes are most commonly responsible for the FH phenotype, which is characterized by an excessive accumulation of low-density lipoprotein cholesterol (LDL-C) in the blood, leading to elevated lifetime risk of atherosclerotic cardiovascular disease (ASCVD) and premature ASCVD (defined as <55 years in men and <65 years in women).
Source: www.lipidjournal.comCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 6Association between Remnant Cholesterol and Incident Atherosclerotic Cardiovascular Disease, Heart Failure, and Atrial Fibrillation - 7 month(s) ago
Atherosclerotic cardiovascular disease (ASCVD) is the most frequent cause of death across the world, and thus we need to keep finding out factors associated with this important outcome1. In addition, the number of patients with heart failure (HF) and atrial fibrillation (AF) has been increasing with our aging societies2–7. Although there are some new medications that can reduce the risk for HF8,9, and now we have useful anti-coagulant therapies10 and more advanced catheter ablation technique for AF11, we need to keep finding out new treatment and prevention targets for HF and AF.
Source: www.lipidjournal.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1Prevalence of lipoprotein(a) measurement in patients with or at risk of cardiovascular disease - 7 month(s) ago
Lipoprotein(a) [Lp(a)] is a genetically determined independent risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve stenosis (CAVS)1-5. Its role in cardiovascular disease is strongly supported by a large body of clinical evidence encompassing observational studies, meta-analyses, genome wide association, and Mendelian randomization studies across multiple populations1. Elevated Lp(a) levels independently predict clinical events related to myocardial infarction, stroke, peripheral arterial disease, and aortic valve stenosis.
Source: www.lipidjournal.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
Obesity, dyslipidemia, and cardiovascular disease: A joint expert review from the Obesity Medicine Association and the National Lipid Association 2024 - Journal of Clinical Lipidology https://t.co/H7AbKWYw4J Pearl of weight reduction and benefits ....