We read with great interest the study by Tas et al. [1], which evaluated a vancomycin stewardship programme in a level IV neonatal intensive care unit (NICU). In their quasi-experimental study, the authors implemented interventions such as staff education, standardized protocols for vancomycin use, and prospective audit and feedback. Their results were impressive; vancomycin initiation decreased by 57%, and total vancomycin days of therapy per 1000 patient-days dropped from 113 to 45 (a 60% reduction).