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Mashup Score: 5Diagnosis and management of endometriosis - 5 month(s) ago
[For a first-person account of endometriosis, see www.cmaj.ca/lookup/doi/10.1503/cmaj.230215][1] KEY POINTS Endometriosis is a chronic condition defined by the presence of endometrial-like tissue outside of the uterus, which can lead to estrogen-driven inflammation. The extent of disease can be
Source: www.cmaj.caCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 2
KEY POINTS Despite serious disruptions to tuberculosis (TB) programs during the COVID-19 pandemic, including in Canada,[1][1] the past few years have also seen global advances in TB treatment. Novel drugs and regimens have been developed to support faster, safer, more effective treatment for drug-
Source: www.cmaj.caCategories: General Medicine News, Hem/OncsTweet-
Time for Canada to align with global innovations in treatment for tuberculosis https://t.co/2sZxS0qAHI via @HealthLawAdamH et al
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Mashup Score: 9Neonatal lupus erythematosus - 6 month(s) ago
A 5-week-old infant boy presented to the dermatology department with a 3-week history of annular plaques. The patient had multiple papules and annular plaques with a raised border on his scalp and face ([Figure 1][1]). His mother had an uncomplicated pregnancy, although she had a history of systemic
Source: www.cmaj.caCategories: General Medicine News, PediatricsTweet-
RT @NICU_Musings: Rash present in a 5 week old for 3 weeks leads to maternal diagnosis. The heart was ok... https://t.co/wvuNfPntur #neoTwi…
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Mashup Score: 396Risk of hospital admission and death from first-ever SARS-CoV-2 infection by age group during the Delta and Omicron periods in British Columbia, Canada - 6 month(s) ago
Background: Population-based cross-sectional serosurveys within the Lower Mainland, British Columbia, Canada, showed about 10%, 40% and 60% of residents were infected with SARS-CoV-2 by the sixth (September 2021), seventh (March 2022) and eighth (July 2022) serosurveys. We conducted the ninth (December 2022) and tenth (July 2023) serosurveys and sought to assess risk of severe outcomes from a first-ever SARS-CoV-2 infection during intersurvey periods. Methods: Using increments in cumulative infection-induced seroprevalence, population census, discharge abstract and vital statistics data sets, we estimated infection hospitalization and fatality ratios (IHRs and IFRs) by age and sex for the sixth to seventh (Delta/Omicron-BA.1), seventh to eighth (Omicron-BA.2/BA.5) and eighth to ninth (Omicron-BA.5/BQ.1) intersurvey periods. As derived, IHR and IFR estimates represent the risk of severe outcome from a first-ever SARS-CoV-2 infection acquired during the specified intersurvey period. Resu
Source: www.cmaj.caCategories: General Medicine News, Expert PicksTweet-
As of July 2023, in British Columbia, 21% of people were seronegative Covid (Novids), nearly double (~40%) among people age 80+. The risk of death and hospitalization for advanced age groups is substantial https://t.co/brr5HPs1Ng @CMAJ https://t.co/ADsDMPoknu
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Mashup Score: 1Predictors of fatal and nonfatal overdose after prescription of opioids for chronic pain: a systematic review and meta-analysis of observational studies - 7 month(s) ago
Background: Higher doses of opioids, mental health comorbidities, co-prescription of sedatives, lower socioeconomic status and a history of opioid overdose have been reported as risk factors for opioid overdose; however, the magnitude of these associations and their credibility are unclear. We sought to identify predictors of fatal and nonfatal overdose from prescription opioids. Methods: We systematically searched MEDLINE, Embase, CINAHL, PsycINFO and Web of Science up to Oct. 30, 2022, for observational studies that explored predictors of opioid overdose after their prescription for chronic pain. We performed random-effects meta-analyses for all predictors reported by 2 or more studies using odds ratios (ORs) and 95% confidence intervals (CIs). Results: Twenty-eight studies (23 963 716 patients) reported the association of 103 predictors with fatal or nonfatal opioid overdose. Moderate- to high-certainty evidence supported large relative associations with history of overdose (OR 5.85
Source: www.cmaj.caCategories: General Medicine News, General HCPsTweet-
CMAJ analysis of 28 studies & 24 million pts Rx opioids suggest a higher risk of opioid overdose w/: high-dose opioids, fentanyl, multiple opioid Rxs, overdose Hx, Dx of substance use, depression, bipolar, mental illness, pancreatitis https://t.co/FprgoaTvXR https://t.co/G0QjNJTezu
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Mashup Score: 95Administration of vasopressors through peripheral venous catheters - 9 month(s) ago
Despite advancements in sepsis management, mortality rates remain high. In 2011, 1 in 18 deaths in Canada involved sepsis.[1][1] Delays in achieving adequate mean arterial pressure (MAP) are associated with increased mortality.[2][2] Therefore, the Surviving Sepsis Campaign guideline recommends
Source: www.cmaj.caCategories: Latest Headlines, PediatricsTweet-
RT @ApoThera: Administration of vasopressors through peripheral venous catheters https://t.co/VIoVDAmDBA #MedTwitter #ICU #FOAMcc #sepsis #…
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Mashup Score: 57Administration of vasopressors through peripheral venous catheters - 9 month(s) ago
Despite advancements in sepsis management, mortality rates remain high. In 2011, 1 in 18 deaths in Canada involved sepsis.[1][1] Delays in achieving adequate mean arterial pressure (MAP) are associated with increased mortality.[2][2] Therefore, the Surviving Sepsis Campaign guideline recommends
Source: www.cmaj.caCategories: Cardiologists, Latest HeadlinesTweet-
RT @ApoThera: Administration of vasopressors through peripheral venous catheters https://t.co/VIoVDAmDBA #MedTwitter #ICU #FOAMcc #sepsis #…
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Mashup Score: 1
Read the related article. Transcript Dr. Mojola Omole: Welcome to the new CMAJ podcast, I’m Dr. Mojola Omole. Dr. Blair Bigham: I’m Dr. Blair Bigham. Long time listeners might notice a few differences to the podcast. We’ve got a new theme, new artwork and a new mission. Dr. Mojola Omole: And then there’s us. Dr. Blair Bigham: Yeah, that’s right. We’re…
Source: www.cmaj.caCategories: Latest Headlines, Oncologists2Tweet-
1st episode of @CMAJ podcast is out! @BlairBigham and myself speak to @AndreaSimpsonMD and @SophiaParkMD about parenthood and a medical career. Let us know what you think! #MedTwitter #WomenInMedicine #infertility #medschool https://t.co/qy6x5QXFPS
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Diagnosis and management of endometriosis https://t.co/K9usAhLsF4 via @DrAllaire et al https://t.co/rze9JUsQzu