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Mashup Score: 1Disentangling Computed Tomography Pattern and Extent to Estimate Prognosis in Fibrosing Interstitial Lung Diseases - 8 hour(s) ago
Clinicians generally have two objectives when evaluating patients with interstitial lung disease (ILD). The first is to assimilate clinical and phenotypic information to confer a singular ILD diagnosis, which broadly informs medical management and estimated prognosis. The second objective is to identify personal factors that necessitate alterations to the standard diagnosis-based management approach. Several studies have demonstrated that information gained from computed tomography (CT) can advance both
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Mashup Score: 9Idiopathic Pulmonary Fibrosis: From Common Microscopy to Single-Cell Biology and Precision Medicine - 21 hour(s) ago
“.” American Journal of Respiratory and Critical Care Medicine, 209(9), pp. 1074โ1081 Correspondence and requests for reprints should be addressed to Moisรฉs Selman, M.D., Instituto Nacional de Enfermedades Respiratorias โIsmael Cosรญo Villegas,โ Tlalpan 4502, CP 14080, Mexico City, Mรฉxico. E-mail: [email protected]. Author Contributions: M.S. and A.P. contributed to the conception and writing of this manuscript. Not Yet Registered? Benefits of Registration Include: โข A Unique User Profile that will allow
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Mashup Score: 13
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive fibrotic lung disease of unknown origin associated with high morbidity, poor survival, and substantial healthcare use (1). Two drugs, nintedanib and pirfenidone, have been shown to slow the rate of functional decline and disease progression and are approved worldwide. However, the condition of most patients continues to decline despite treatment, and both drugs are associated with substantial tolerability issues. The IPF community is
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Mashup Score: 15Proteomic Biomarkers of Survival in Idiopathic Pulmonary Fibrosis - 24 hour(s) ago
Rationale: Idiopathic pulmonary fibrosis (IPF) causes progressive lung scarring and high mortality. Reliable and accurate prognostic biomarkers are urgently needed. Objectives: To identify and vali…
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Mashup Score: 6Zinpentraxin Alfa for Idiopathic Pulmonary Fibrosis: The Randomized Phase III STARSCAPE Trial - 24 hour(s) ago
Rationale: A phase II trial reported clinical benefit over 28โweeks in patients with idiopathic pulmonary fibrosis (IPF) who received zinpentraxin alfa. Objectives: To investigate the efficacy and …
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Mashup Score: 0Gazing into the Proteomic Crystal Ball: Predicting Survival in Idiopathic Pulmonary Fibrosis - 1 day(s) ago
In many respects, idiopathic pulmonary fibrosis (IPF) is a predictable disease. It is a condition characterized by inevitable and usually inexorable progression with an untreated median survival of between 3 and 5 years (1). However, a look beyond population-level statistics and examination of the disease behavior of individual patients reveals considerable heterogeneity. Some individuals have rapidly progressive disease and die within months of diagnosis, whereas others have relatively indolent disease,
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Mashup Score: 2Validation of Constant Work Rate Cycling Endurance Time for Use in Chronic Obstructive Pulmonary Disease Clinical Trials - 1 day(s) ago
Rationale: A COPD Foundation working group sought to identify measures of exercise endurance, a meaningful aspect of physical functioning in everyday life among patients with chronic obstructive pu…
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Mashup Score: 14
Rationale: Oral microbiota associate with diseases of the mouth and serve as a source of lung microbiota. However, the role of oral microbiota in lung disease is unknown. Objectives: To determine a…
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Mashup Score: 1Mandibular Jaw Movement Automated Analysis for Oral Appliance Monitoring in Obstructive Sleep Apnea: A Prospective Cohort Study - 2 day(s) ago
Rationale: Oral appliances are second-line treatments after continuous positive airway pressure for obstructive sleep apnea (OSA) management. However, the need for oral appliance titration limits t…
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Mashup Score: 1
Rationale: Computed tomography (CT) enables noninvasive diagnosis of usual interstitial pneumonia (UIP), but enhanced image analyses are needed to overcome the limitations of visual assessment. Obj…
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Disentangling Computed Tomography Pattern and Extent to Estimate Prognosis in Fibrosing Interstitial Lung Diseases ๐ Open Access ๐ https://t.co/u3TylSHBFB