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Mashup Score: 3Therapy for Chikungunya Arthritis: A Study of 133 Brazilian Patients - 1 month(s) ago
ABSTRACT. Chikungunya fever is a global vector-borne viral disease. Patients with acute chikungunya are usually treated symptomatically. The arthritic phase may be self-limiting. However, many patients develop extremely disabling arthritis that does not improve after months. The aim of this study was to describe the treatment of chikungunya arthritis (CHIKA) patients. A medical records review was conducted in 133 CHIKA patients seen at a rheumatology practice. Patients were diagnosed by clinical criteria and confirmed by the presence of anti-chikungunya IgM. Patients were treated with methotrexate (20 mg/week) and/or leflunomide (20 mg/day) and dexamethasone (0–4 mg/day) for 4 weeks. At baseline visit and 4 weeks after treatment, Disease Activity Score 28 (DAS28) and pain (using a visual analog scale) were ascertained. Five months after the end of treatment, patients were contacted to assess pain, tender joint count, and swollen joint count. The mean age of patients was 58.6 ± 13.7 yea
Source: www.ajtmh.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 4Review of Cases of Angiostrongyliasis in Hawaii, 2007–2017 - 4 month(s) ago
Angiostrongyliasis, caused by the Angiostrongylus cantonensis roundworm, became reportable in the state of Hawaii in 2007. We confirmed 82 reported cases between 2007 and 2017. There was a median of seven cases per year, and the majority (57%) of cases occurred between January and April. Most (83%) cases were found on the island of Hawaii, with geographic information system (GIS) analysis identifying hot spots on the east side of the island. However, cases were identified on the other major islands as well, suggesting the risk of exposure is present statewide. Comparisons of cases from 2007 to 2017 with cases from previous assessments found no statistical differences in cerebrospinal fluid results, peripheral blood results, or ages of cases. However, differences in geographic distribution of the cases were statistically significant. Improved testing and increasing awareness of the disease have contributed to our efforts to better understand the general risk factors and modes of transmi
Source: www.ajtmh.orgCategories: General Medicine News, Infectious DiseaseTweet-
#Angiostrongylus #cantonensis 1. SE Asia/Pacific Islands 2. Ingest snails, slugs, contaminated food, infected crab/shrimp 3. Larva neurotrophic: common parasite cause eosinophilic meningitis 4.Dx serology/PCR 5. Rx supportive; self-limited; steroids https://t.co/BzUmP75CAV
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Mashup Score: 11The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries - 8 month(s) ago
The 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus’s natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging zoonotic pathogens to address them locally and prevent or quickly control their worldwide spread. Political endorsement from individual countries and financial commitments to maintain control efforts will be essential for long-term sustainability.
Source: www.ajtmh.orgCategories: Latest Headlines, Partners & KOLsTweet-
The Human Mpox Global Outbreak: The global outbreak from 2022-2023 which occurred mainly among gay men subsided with immunity from vaccines & natural infection. However, Mpox still endemic in West & Central Africa- need global equity in vaccines https://t.co/PtG3X458k1
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Mashup Score: 2
The Walter Reed Army Institute of Research (WRAIR) supports more than 350,000 people on lifesaving HIV treatment in Kenya, Nigeria, Tanzania, and Uganda through funding from the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). Here, we review and synthesize the range of impacts WRAIR’s implementation science portfolio has had on PEPFAR service delivery for military and civilian…
Source: www.ajtmh.orgCategories: Cardiologists, Latest HeadlinesTweet-
New @WalterReedArmy @PEPFAR: A Must Read. 15 years of insights and best practices- #implementation of #PEPFAR programs among #military & #civilian #communities in #Nigeria #Kenya #Tanzania #Uganda #Africa. #BestBuy #ImpSci #GlobalHealth @DeptofDefense @NIH https://t.co/gbBzQdhupi https://t.co/0Lm52FKtMq
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Mashup Score: 104
We studied sources of variation between countries in per-capita mortality from COVID-19 (caused by the SARS-CoV-2 virus). Potential predictors of per-capita coronavirus-related mortality in 200 countries by May 9, 2020 were examined, including age, gender, obesity prevalence, temperature, urbanization, smoking, duration of the outbreak, lockdowns, viral testing, contact-tracing policies, and…
Source: www.ajtmh.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
Was a preprint, now peer-rev'd: "In countries with cultural norms or government policies supporting public mask-wearing, per-capita coronavirus mortality increased on average by just 16.2% each week, compared with 61.9% each week in remaining countries." https://t.co/JFS77dzmdS
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Mashup Score: 11
Infodemics, often including rumors, stigma, and conspiracy theories, have been common during the COVID-19 pandemic. Monitoring social media data has been identified as the best method for tracking rumors in real time and as a possible way to dispel misinformation and reduce stigma. However, the detection, assessment, and response to rumors, stigma, and conspiracy theories in real time are a…
Source: www.ajtmh.orgCategories: Cardiologists, Latest HeadlinesTweet-
RT @sminaev2015: COVID-19–Related Infodemic and Its Impact on Public Health: A Global Social Media Analysis https://t.co/OrqFEvDwCT
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Mashup Score: 5
Infodemics, often including rumors, stigma, and conspiracy theories, have been common during the COVID-19 pandemic. Monitoring social media data has been identified as the best method for tracking rumors in real time and as a possible way to dispel misinformation and reduce stigma. However, the detection, assessment, and response to rumors, stigma, and conspiracy theories in real time are a…
Source: www.ajtmh.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
COVID-19–Related Infodemic and Its Impact on Public Health: A Global Social Media Analysis https://t.co/OrqFEvDwCT
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Mashup Score: 54
Infodemics, often including rumors, stigma, and conspiracy theories, have been common during the COVID-19 pandemic. Monitoring social media data has been identified as the best method for tracking rumors in real time and as a possible way to dispel misinformation and reduce stigma. However, the detection, assessment, and response to rumors, stigma, and conspiracy theories in real time are a…
Source: www.ajtmh.orgCategories: Infectious Disease, Latest HeadlinesTweet-
This study evaluates #COVID19 misinformation in social media. In ~3 months, they identified 2,311 reports of rumors, stigma & conspiracy theories in 25 languages from 87 countries. 1,856 (82%) of these claims were false. Table 2 is illuminating. https://t.co/lnVuXPXEuA https://t.co/gbRr4eauxP
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Mashup Score: 9
Infodemics, often including rumors, stigma, and conspiracy theories, have been common during the COVID-19 pandemic. Monitoring social media data has been identified as the best method for tracking rumors in real time and as a possible way to dispel misinformation and reduce stigma. However, the detection, assessment, and response to rumors, stigma, and conspiracy theories in real time are a…
Source: www.ajtmh.orgCategories: Healthcare Professionals, Latest HeadlinesTweet-
"#COVID19–Related #Infodemic and Its Impact on Public Health: A Global Social Media Analysis" https://t.co/QJ7Dg5ZXgi cc @srmarcon @ChristenRachul "#Misinformation fueled by rumors, stigma, & conspiracy theories can have potentially serious implications..." #CheckThenShare https://t.co/cjWA6qxlXJ
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Mashup Score: 1I Never Thought I Had “Moral Courage,” until COVID-19 Happened | The American Journal of Tropical Medicine and Hygiene - 4 year(s) ago
I Never Thought I Had “Moral Courage,” until COVID-19 Happened
Source: www.ajtmh.orgCategories: Latest Headlines, PediatricsTweet-
The #Power of #scicomm! My @AJTMH story from the field highlights a few learnings during the struggles to develop #COVID19 #vaccines. 1- be prepared for stumbling blocks 2) communicate effectively and 3) never give up when the times get tough. https://t.co/Q9xZVmhTgH https://t.co/4MnjIKHEZS
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Chikungunya Arthritis - 2 studies show benefit of dexamethosone (up to 4mg/d) w/ improved DAS28 scores; Uncertain benefit however with MTX; 133 Brazilian pts studied for 5 mos & 31 pts studied for 8wks. https://t.co/Ko3aRYX0xi https://t.co/rtC4RCRjnU https://t.co/XOoFYw0dR4