• Mashup Score: 8
    Contents | Science Immunology 7, 77 - 2 year(s) ago

    Science Immunology Volume 7|Issue 77|Nov 2022 ONLINE COVER Rejuvenation Potential of TRM Subsets. This month’s cover depicts a “fountain of youth” from which new tissue resident memory T cells (TRM) are emerging after a secondary infectious challenge. Newly formed CD103– TRM (blue) and CD103+ TRM (red) are derived from proliferating, CD103– precursor cells and join the pool…

    Source: Science Immunology
    Categories: Allergy-Immunology, Latest Headlines
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      SciImmunology

      November's Science #Immunology issue is out! The cover studies feature new fate-mapping mouse models that depict how new tissue resident memory #Tcells can emerge after reinfection. https://t.co/LVIZJ6nwpU https://t.co/sLz4wF2rgH

  • Mashup Score: 4
    Contents | Science Immunology 7, 76 - 2 year(s) ago

    Science Immunology Volume 7|Issue 76|Oct 2022 ONLINE COVER Mangled Myelin. This month’s cover depicts a normal myelin sheath wrapped around the axon of a neuron next to a damaged myelin sheath impairing nerve function. Autoreactive T cells specific for epitopes in myelin proteins trigger demyelination in human multiple sclerosis and mice with experimental autoimmune…

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    Categories: Allergy-Immunology, Latest Headlines
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      SciImmunology

      October's Science #Immunology issue is out! The cover study uses CAR T cell therapy to regulate self-reactive #Tcells, preventing onset and reversing progression of #MultipleSclerosis-like disease in mice. Other work examines immunity in fatty tissues. https://t.co/VjSyfsrHwx https://t.co/G9RUyPAIaS

  • Mashup Score: 5
    Contents | Science Immunology 7, 75 - 2 year(s) ago

    Research Articles Diurnal rhythms in intestinal IgA act to cross-regulate oscillations in the abundance of commensal microbes to foster mutualism. We share a method called DITAS for the identification of tumor antigens in immune checkpoint blockade-treated cancer patients. …

    Source: Science Immunology
    Categories: Allergy-Immunology, Latest Headlines
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      SciImmunology

      ICYMI: The September issue for Science #Immunology is now out! The cover article studies how clock genes and feeding cues impact IgA secretion in the gut of mice. Other work examines ICB therapy and immune-related adverse events. 📢Read more: https://t.co/YakYvqPTRM https://t.co/k3GGLYUyX8

  • Mashup Score: 1
    Contents | Science Immunology 7, 75 - 2 year(s) ago

    Research Articles Diurnal rhythms in intestinal IgA act to cross-regulate oscillations in the abundance of commensal microbes to foster mutualism. We share a method called DITAS for the identification of tumor antigens in immune checkpoint blockade-treated cancer patients. …

    Source: Science Immunology
    Categories: Future of Medicine, Latest Headlines
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      SciRobotics

      📢 The September issue for Science #Immunology is now out! The cover article studies how clock genes and feeding cues impact IgA secretion in the gut of mice. Other work examines ICB therapy and immune-related adverse events. Check it out here ➡️ https://t.co/l5bV0OkkZN https://t.co/cfkJg8QX28

  • Mashup Score: 7
    Contents | Science Immunology 7, 74 - 2 year(s) ago

    Science Immunology Volume 7|Issue 74|Aug 2022 ONLINE COVER Exclusion of CD45 from a CAR-T Synapse. This month’s cover features a confocal microscopy image in which a human T cell expressing a CD19-targeting chimeric antigen receptor (CAR), stained in red, has formed an immunological synapse with a human Raji B cell lymphoma cell (blue). CD45 (green), a bulky tyrosine…

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      SciImmunology

      The August issue of Science #Immunology is out! The cover study examines CAR T activation and protein size. Other research spotlights autoreactive #Bcells and exhausted #Tcells. Read more⤵️ https://t.co/pR7Xb1oWxg https://t.co/xVk7ndovQX

  • Mashup Score: 7
    Contents | Science Immunology 7, 73 - 3 year(s) ago

    Focus Androgen signaling compromises CD8+ T cell effector functions and contributes to sex-biased outcomes in many forms of cancer. Research Articles TH17-deficient conditional knockout mice lacking Rorc in T cells exhibit…

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    Categories: Allergy-Immunology, Latest Headlines
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      SciImmunology

      The July issue of Science #Immunology is out! The cover article delves into sex-bias in #cancer occurrence and mortality. Other studies feature alveolar macrophages and IgA oral #immunity. Learn more➡️ https://t.co/KvftK5Kwun https://t.co/LcerFKIYna

  • Mashup Score: 15
    Contents | Science Immunology 7, 71 - 3 year(s) ago

    Research Articles Zbtb20 expression identifies and is important for the function of a subset of Tregs involved in intestinal integrity. Targeting TLR4 with GLA-SE boosts lymphoid stromal cell and GC responses to protein immunization in aged…

    Source: Science Immunology
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      SciImmunology

      The May issue of Science #Immunology is out! The cover article finds mice with a #booster in the same limb as their first #immunization had a stronger #AdaptiveImmunity response. Other work explores weakened #immunity and #aging. Read more ➡️ https://t.co/41g5x7Qzaf https://t.co/mKxKAFKhDS

  • Mashup Score: 10
    Contents | Science Immunology 7, 70 - 3 year(s) ago

    Focus Nixon et al. demonstrate a cytotoxic program that distinguishes group 1 innate lymphoid cells from classical natural killer cells across multiple tissues in mice. Single-cell transcriptomic data identifies major…

    Source: Science Immunology
    Categories: Allergy-Immunology, Latest Headlines
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      SciImmunology

      🎉 @SciImmunology has passed 40K followers 🎉 Thanks to all for your interest in the journal’s #science and #immunology. Check out the current issue 🔀 https://t.co/7F3bHLalwb! If you’ve published with us lately, leave a link ⤵️

  • Mashup Score: 21
    Contents | Science Immunology 7, 70 - 3 year(s) ago

    Focus If EBV is a “driver” of MS by inducing antiviral immunity with associated autoimmunity, elimination of EBV may be a rational therapy. Reviews Recent advances on human dendritic cells have opened new avenues…

    Source: Science Immunology
    Categories: Allergy-Immunology, Latest Headlines
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      SciImmunology

      The April issue of Science #Immunology is out! The cover article defines how #Tcell proximity can influence #cancer #immunotherapy outcomes in #melanoma tumors. Other work explores how T cells recruit #Bcells in such contexts. Read more ➡️ https://t.co/PP5Z74t3tf https://t.co/rk8Fp7XLW4

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